Results 41 to 50 of about 11,029 (284)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Assessment of Knowledge of Histamine Fish Poisoning Among Health Care Personnel and Fish Consumers in Dar es salaam Region [PDF]

, 2012
Histamine fish poisoning which is also called scombroid fish poisoning is a mild to moderate form of food poisoning caused by eating spoiled or bacterial contaminated fish after capture or during subsequent handling and storage.
Bulula, N., Bulula, Ngwegwe
core  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

FEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz, Mihály Mérey, Rebeka Vásárhelyi, Ramóna Pék, Victor Imburchia, László Henn, Adrián Kószó, Nicholas D. Lakin, Ivan Ahel, Sébastien Huet, Ágnes Czibula, Gyula Timinszky   +11 more
wiley   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

FEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

Monitoring, source apportionment, and health risk implications of potentially toxic element concentrations in canned fish products within Kumasi metropolis, Ghana

Food Chemistry Advances
Canned fish is widely consumed in Ghana due to its low cost, long shelf life, and nutritional value. However, concerns over potentially toxic elements (PTE) pose a growing public health risk.
Gerheart Winfred Ashong, Wisdom Kwame Nyatuame, Flora Amerley Amarh, Dogbey Bright Agbeko, Ray Bright Voegborlo, Eric Selorm Agorku, Michael Yaw Peasah   +6 more
doaj   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

FEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure, Misaki K. Nishio, Satoru Okuda, Kohji Hotta   +3 more
wiley   +1 more source

Heavy metal contamination during processing of canned fish: a review on food health and food safety [PDF]

, 2023
Fish in cans is more popular than ever because of its convenience, improved quality, less risk of contamination, and long shelf life. To preserve seafood products, the canning process uses a hermetic closure and thermal techniques. Tuna, salmon, mackerel,
Roslianah, Asdari, Mohammad Bodrul, Munir, Ahmed Jalal Khan, Chowdhury, Md. Masud, Rana   +3 more
core   +1 more source

Feasibility Study of Canned Smoked Fish as the Micro Enterprises in South Sumatra Province, Indonesia

Jurnal Optimasi Sistem Industri, 2022
This paper analyzes several aspects (technical, marketing, economic, social, and financial) of canned smoked fish (Pangasius) as a micro-industry in South Sumatra Province, Indonesia. This article adopts mix-methods.
Hasmawaty, Christofora Desi Kusmindari, Muhammad Faizal   +2 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

FEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai, Mohyeddine Omrane, Nassima Benzoubir, Didier Samuel, Ama Gassama‐Diagne   +4 more
wiley   +1 more source