Results 31 to 40 of about 477,421 (267)

A Method for the Coefficient Superposition Buckling Bearing Capacity of Thin-Walled Members

open access: yesBuildings
Axial compression tests were conducted on short rhombic tubes of different cross-sectional shapes. The deformation modes of the rhombic short tubes were obtained.
Bing Xu   +5 more
doaj   +1 more source

A Review of Water Environmental Capacity Calculation [PDF]

open access: yesE3S Web of Conferences, 2019
Water environmental capacity is an essential component of water environmental assessment and must be monitored and managed for economic, engineering, and human health reasons.
Yuan Jing   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Airport Capacity Prediction and Optimization Based on Semi-Varying Coefficient and Dynamic Programming

open access: yesIEEE Access
Air traffic congestion has emerged as a critical challenge in modern air traffic management. Adverse weather conditions and other factors frequently lead to reduced airport arrival capacity, resulting in flight delays.
Huan Xia   +4 more
doaj   +1 more source

Probabilistic Bearing Capacity of a Pavement Resting on Fibre Reinforced Embankment Considering Soil Spatial Variability

open access: yesFrontiers in Built Environment, 2021
This paper intends to examine the influence of spatial variability of soil properties on the probabilistic bearing capacity of a pavement located on the crest of a fibre reinforced embankment.
Kouseya Choudhuri, Debarghya Chakraborty
doaj   +1 more source

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

open access: yesFEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

open access: yesFEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri   +5 more
wiley   +1 more source

Measurement of physical properties of polyurethane plaster

open access: yesGrađevinar, 2014
Physical properties of building materials can be defined by material coefficients. The material coefficients examined were: coefficient of mean density, coefficient of specific heat capacity, coefficient of thermal conductivity, and coefficient of ...
Milena Kušnerová   +2 more
doaj   +1 more source

Translophagy—A potential link between autophagy impairment and translational errors

open access: yesFEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk   +11 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

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