Results 91 to 100 of about 75,323 (218)

Adverse Interaction between Capecitabine and Warfarin Resulting in Altered Coagulation Parameters: A Review of the Literature Starting from a Case Report

Case Reports in Medicine, 2010
Capecitabine is an orally active prodrug of fluorouracil and is extensively used as an antineoplastic agent. It is converted to 5-Fluorouracil in the liver and tumor tissues.
Giovanni Giunta
doaj   +1 more source

Impact of Metformin and Diabetes on Tumor Response to Total Neoadjuvant Therapy in Advanced Rectal Cancer: A Multicenter Retrospective Cohort Study

Asia-Pacific Journal of Clinical Oncology, EarlyView.
In advanced rectal cancer patients receiving total neoadjuvant therapy (TNT), overall tumor response did not differ by diabetes status or metformin use. However, among diabetic patients, metformin use was associated with higher overall complete response rates. These findings suggest a potential benefit of metformin in enhancing TNT response in diabetic
Sergei Bedrikovetski, Mahima Raju, Tracy Fitzsimmons, Ishraq Murshed, Timothy J. Price, Michael Penniment, Sudarsha Selva‐Nayagam, Tarik Sammour   +7 more
wiley   +1 more source

Targeting hexokinase 2 to induce breast cancer cell senescence

British Journal of Pharmacology, EarlyView.
Background and Purpose Hexokinase 2 (HK2) is a key enzyme linked to high tumour cell proliferation. Its inhibitors such as 3‐bromopyruvic acid (3‐BP) induce cancer cell death, highlighting HK2 modulation as potential anti‐cancer treatment. However, standard chemotherapies often cause the emergence of senescent cancer cells, which goes along with cell ...
Helmut Bischof, Katarina Cisarova, Sandra Burgstaller, Mia Schwerer, Markus Absenger‐Novak, Philipp J. Jost, Roland Malli, Wolfgang F. Graier, Robert Lukowski   +8 more
wiley   +1 more source

044. Unlocking The Potential: Comparing The Effects of Probiotics Alone and in Combination with Capecitabine Against Colorectal Cancer in Rats

JBN (Jurnal Bedah Nasional)
Background: Colorectal cancer (CRC) is a leading cause of cancer deaths globally. While capecitabine is an effective chemotherapy for CRC, its use is limited by side effects and resistance. This has sparked interest in combining capecitabine with natural
Reza Yuneri Putri, Suci Berlian Hemilton, Muhammad Iqbal Rivai, Rini Suswita, Irwan Irwan, Avit Suchitra   +5 more
doaj   +1 more source

Perspectives of Older Patients on the Complexity of Medication Use

Journal of the American Geriatrics Society, EarlyView.
ABSTRACT Background Medication use complexity is associated with non‐adherence, hospitalizations, and lower quality of life. It is most frequently measured with the Medication Regimen Complexity Index (MRCI). This instrument estimates the complexity of a patient's medication regimen, taking into account the pharmaceutical dosage forms and routes ...
Charlotte M. Falke, Mariëlle F. J. Koolen, Samuel L. Timmer, Fatma Karapinar‐Çarkit, Marcel L. Bouvy, Antoine C. G. Egberts, Wilma Knol   +6 more
wiley   +1 more source

Treatment landscape from first‐ to third‐line therapy and quality of life data of patients with pancreatic cancer from the prospective German PARAGON (Platform for Outcome, Quality of Life, and Translational Research on Pancreatic Cancer) registry (IKF‐PARAGON study)

International Journal of Cancer, Volume 158, Issue 10, Page 2560-2570, 15 May 2026.
What's New? Pancreatic cancer often is diagnosed at advanced stages. As a result, treatment regimens frequently are aggressive, with substantial side effects that impact quality of life (QoL). This study examined the treatment landscape, from neoadjuvant therapy to palliative care, in the context of QoL among pancreatic cancer patients in Germany. Most
Thorsten O. Goetze, Salah‐Eddin Al‐Batran, Ruediger Liersch, Lars Scheuer, Thomas Goehler, Ulrich Kaiser, Claudio Denzlinger, Stephan Brandl, Daniel Pink, Jens Uhlig, Michael Maasberg, Maria Loose, Marina Schaaf, Disorn Sookthai, Bianca Zäpf, Claudia Pauligk, Timursah Habibzade, Ralf‐Dieter Hofheinz, Christine Koch, for the AIO Study Group   +19 more
wiley   +1 more source

Photosensitive lichenoid skin reaction to capecitabine

BMC Cancer, 2017
Background Capecitabine is an oral prodrug of fluorouracil, which is a common agent used in the management of many solid tumor malignancies. Dermatologic reaction is common with various chemotherapy agents but is not commonly reported in the use of ...
Rena A. Shah, Daniel D. Bennett, Mark E. Burkard   +2 more
doaj   +1 more source

A case of abdominal sarcoidosis in a patient with acute myeloid leukemia. [PDF]

, 2013
The allogeneic bone marrow transplantation usually preceded by induction chemotherapy, in fit patients, represents the gold standard in the acute myeloid leukaemia.
Addeo, Alfredo, Athithan, Lavanya, Baskaran, Vadsala, Goodwin, Amanda, Rinaldi, Ciro   +4 more
core   +2 more sources

Efficacy and Safety of Envafolimab Combined With Capecitabine and Lenvatinib as Postoperative Adjuvant Therapy in Resected Biliary Tract Cancer With High‐Risk Recurrence Factors: A Phase II Single‐Center Prospective Study

Cancer Medicine, Volume 15, Issue 4, April 2026.
A phase II single‐center prospective study evaluating envafolimab combined with capecitabine and lenvatinib as postoperative adjuvant therapy in resected biliary tract cancer with high‐risk recurrence factors. The regimen demonstrated encouraging efficacy (median DFS 15.6 months; 1‐year DFS 68.3%; 1‐year OS 91.4%) and manageable safety, with no ...
Yitong Tian, Tian Lei, Qingyang Ruan, Xueying Zhou, Ruijing Shen, Tianao Xie, Shijie Li, Xiujun Cai, Mingyu Chen   +8 more
wiley   +1 more source

High incidence of Angina pectoris in patients treated with 5-fluorouracil - A planned surveillance study with 102 patients [PDF]

, 2003
Objective: Angina pectoris, arrhythmic sudden death and myocardial infarction, all these cardiac events have occasionally been reported during 5-fluorouracil (5-FU) chemotherapy.
Lersch, C., Reindl, L., Scherpinski, U., Seyfarth, M., Wacker, A.   +4 more
core   +1 more source