Results 151 to 160 of about 47,826 (189)
Some of the next articles are maybe not open access.
Clinical Therapeutics, 2005
Fluorouracil (FU) is an antimetabolite with activity against numerous types of neoplasms, including those of the breast, esophagus, larynx, and gastrointestinal and genitourinary tracts. Systemic toxicity, including neutropenia, stomatitis, and diarrhea, often occur due to cytotoxic nonselectivity.
Christine M, Walko, Celeste, Lindley
exaly +3 more sources
Fluorouracil (FU) is an antimetabolite with activity against numerous types of neoplasms, including those of the breast, esophagus, larynx, and gastrointestinal and genitourinary tracts. Systemic toxicity, including neutropenia, stomatitis, and diarrhea, often occur due to cytotoxic nonselectivity.
Christine M, Walko, Celeste, Lindley
exaly +3 more sources
Drugs, 1999
Capecitabine is an orally administered fluoropyrimidine carbamate used for the treatment of paclitaxel- or anthracycline-refractory breast cancer. Capecitabine is metabolised via a 3-step process to the active agent fluorouracil. The final step of this process occurs preferentially in malignant tissue.
M, Dooley, K L, Goa
openaire +2 more sources
Capecitabine is an orally administered fluoropyrimidine carbamate used for the treatment of paclitaxel- or anthracycline-refractory breast cancer. Capecitabine is metabolised via a 3-step process to the active agent fluorouracil. The final step of this process occurs preferentially in malignant tissue.
M, Dooley, K L, Goa
openaire +2 more sources
Reactions Weekly, 2010
The extent of Organic Chemistry has critical impact today on teaching Advanced Medicinal Chemistry. In this paper, an alternative approach to learn retrosynthetic analysis through problem solving and collaborative learning is presented. Thus, an anticancer drug, Capecitabine (Xeloda) is used to illustrate the potential of Problem Based Learning (PBL ...
Ana Alcudia +2 more
+4 more sources
The extent of Organic Chemistry has critical impact today on teaching Advanced Medicinal Chemistry. In this paper, an alternative approach to learn retrosynthetic analysis through problem solving and collaborative learning is presented. Thus, an anticancer drug, Capecitabine (Xeloda) is used to illustrate the potential of Problem Based Learning (PBL ...
Ana Alcudia +2 more
+4 more sources
Investigational New Drugs, 2000
Drug development has undergone rapid shifts in methodology and the use of rationally derived agents which either target specific tissues or molecules such as receptors or enzymatic sites. Capecitabine is a rationally derived prodrug of 5-fluorouracil which is based upon the known high concentration of the enzyme thymidine phosphorylase in many human ...
openaire +2 more sources
Drug development has undergone rapid shifts in methodology and the use of rationally derived agents which either target specific tissues or molecules such as receptors or enzymatic sites. Capecitabine is a rationally derived prodrug of 5-fluorouracil which is based upon the known high concentration of the enzyme thymidine phosphorylase in many human ...
openaire +2 more sources
Capecitabine leukoencephalopathy
Practical Neurology, 2019Zeid, Yasiry +3 more
openaire +2 more sources