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Capripoxvirus vectors for vaccine development

Gene Reports, 2020
Abstract The Capripoxvirus genus of the Poxviridae family comprises sheep poxvirus, goat poxvirus, and lumpy skin disease virus, which are the causative agents of economically important diseases of ruminants. Live attenuated capripoxvirus vaccines have been used for many years in veterinary practice, and have demonstrated their safety, reliability ...
Olga Chervyakova   +4 more
openaire   +1 more source

Multiple accurate and sensitive arrays for Capripoxvirus (CaPV) differentiation

Analytica Chimica Acta, 2023
Capripoxvirus (CaPV) contains three viruses that have caused massive losses in the livestock and dairy industries. Accurate CaPV differentiation has far-reaching implications for effectively controlling outbreaks. However, it has a great challenge to distinguishing three viruses due to high homology of 97%.
Gaihua, Cao   +7 more
openaire   +2 more sources

Improved detection of capripoxvirus in biopsy samples by PCR

Journal of Virological Methods, 1998
A simple test based on the polymerase chain reaction (PCR) was used to detect capripoxvirus DNA in tissue culture supernatants and biopsy samples. The identity of the PCR products was confirmed by restriction enzyme analysis. The test has greater sensitivity and good specificity compared to an antigen trapping enzyme-linked immunosorbent assay which ...
D C, Ireland, Y S, Binepal
exaly   +3 more sources

Capripoxvirus and Orf Virus

2020
Capripox infections of small ruminants, namely goatpox and sheeppox, are OIE notifiable and transboundary animal diseases. Goatpox and sheeppox are prevalent in some parts of Africa, the Middle East, and Asia with occasional outbreaks in regions of Europe.
Gnanavel Venkatesan   +4 more
openaire   +1 more source

Comparison of the external dimensions of capripoxvirus isolates

Research in Veterinary Science, 1986
No significant difference was found between the external dimensions of the M forms of isolates of sheep pox virus from Nigeria, sheep and goat pox virus from Kenya and lumpy skin disease virus from South Africa. Earlier reports that isolates of capripoxvirus can be distinguished by their relative sizes could not be substantiated.
R P, Kitching, C, Smale
openaire   +2 more sources

A comparison of the genome organization of capripoxvirus with that of the orthopoxviruses

Journal of Virology, 1989
Comprehensive comparisons of genome organizations for poxviruses of different genera have not previously been reported. Here we have made such a comparison by cross-hybridizing genome fragments from capripoxvirus KS-1 and vaccinia virus WR (VV).
P D, Gershon, D M, Ansell, D N, Black
openaire   +2 more sources

Physical characterization of the genome of a cattle isolate of capripoxvirus

Virology, 1987
HindIII, Pstl, Aval, and SalI site maps have been determined for the genome of a cattle isolate of capripoxvirus, KC-1. The length of the genome was estimated, by summation of the lengths of individual HindIII fragments, to be 145.6 kb, and the genome was shown to possess terminally repeated regions 1.13-6.23 kb in length.
P D, Gershon, D N, Black
openaire   +2 more sources

Control of capripoxvirus infections

Vaccine, 1993
The capripoxviruses cause the most severe pox diseases of animals. Epidemiologically the diseases of sheep pox, goat pox and lumpy skin disease differ, but all three viruses may be mechanically transmitted by biting insects, and control without vaccination is extremely difficult in endemic areas. Recently developed live attenuated vaccines provide good,
openaire   +2 more sources

Use of a recombinant antigen in an indirect ELISA for detecting bovine antibody to capripoxvirus

Journal of Virological Methods, 1994
The gene coding for the capripoxvirus structural protein P32 was cloned, expressed in Escherichia coli as a fusion protein with glutathione-S-transferase, and purified on glutathione Sepharose. An indirect enzyme linked immunosorbent assay (ELISA) using this antigen was developed to screen bovine sera for antibodies to capripoxvirus.
R P Kitching, R P Kitching, V M Carn
exaly   +3 more sources

Capripoxvirus-vectored vaccines against livestock diseases in Africa

Antiviral Research, 2013
Five different viral diseases of livestock, lumpy skin disease (LSD), sheep pox (SPP), goat pox (GTP), Rift Valley fever (RVF) and peste des petits ruminants (PPR), circulate in the same regions of Africa, imposing a major burden on economic activity and public health.
Hani, Boshra   +9 more
openaire   +2 more sources

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