Results 61 to 70 of about 1,887 (198)

Research Review on Inhibitors of Lumpy Skin Disease Virus: From Biological Characteristics, Drug Repurposing, to Computer‐Aided Drug Design

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
This review summarizes the research progress on inhibitors of lumpy skin disease virus (LSDV), focusing on its biological characteristics and key proteins involved in the viral replication cycle. It compiles various inhibitors (direct‐acting poxvirus inhibitors and host‐directed poxvirus inhibitors) against poxviruses, their mechanisms of action, and ...
Leilei ZHAO, Jing QU, Miao AN, Yang LIU, Xiubo LI, Yiming LIU, Chen PENG, Todd R. Callaway   +7 more
wiley   +1 more source

Species‐specific inhibition of capripoxvirus replication by host antiviral protein kinase R [PDF]

Annals of the New York Academy of Sciences, 2018
AbstractThe role of interferon (IFN)‐induced protein kinase R (PKR) in capripoxvirus (CaPV)‐infected cells remains unknown. In this study, we show that CaPV infection triggered PKR and eukaryotic translation initiation factor 2 alpha (eIF2α) protein phosphorylation in a dose‐dependent manner, and that this leads to decreased CaPV replication ...
Zhao, Zhixun, Zhu, Xueliang, Wu, Na, Qin, Xiaodong, Huang, Caiyun, Wu, Guohua, Zhang, Qiang, Zhang, Zhidong   +7 more
openaire   +2 more sources

Whole Genome Sequencing of Lumpy Skin Disease Virus from 2021–2023 in Eastern Eurasia Reveals No More Recombination Signals in the Circulating Pool of Strains

Viruses
Having spanned thousands of kilometers from Africa through Europe, the Middle East, Central Asia through to the south eastern part of Eurasia in the recent decade, lumpy skin disease virus has now become entrenched in China, Thailand, Vietnam, and South ...
Alexander Sprygin, Alena Krotova, Ma Jun, Olga Byadovskaya, Vladimir Kirpichenko, Jinchao Chen, Tserenchimed Sainnokhoi, Ilya Chvala   +7 more
doaj   +1 more source

Poxvirus Infections in Dairy Farms and Transhumance Cattle Herds in Nigeria

Viruses, 2023
Lumpy Skin disease (LSD) is an economically important disease in cattle caused by the LSD virus (LSDV) of the genus Capripoxvirus, while pseudocowpox (PCP) is a widely distributed zoonotic cattle disease caused by the PCP virus (PCPV) of the genus ...
David Oludare Omoniwa, Irene Kasindi Meki, Caleb Ayuba Kudi, Anthony Kojo Sackey, Maryam Aminu, Adeyinka Jeremy Adedeji, Clement Adebajo Meseko, Pam Dachung Luka, Olayinka Oluwafemi Asala, Jolly Amoche Adole, Rebecca Bitiyong Atai, Yakubu Joel Atuman, Tirumala Bharani Kumar Settypalli, Giovanni Cattoli, Charles Euloge Lamien   +14 more
doaj   +1 more source

Rescue of recombinant peste des petits ruminants virus: creation of a GFP-expressing virus and application in rapid virus neutralization test [PDF]

, 2012
Peste des petits ruminants virus (PPRV) causes high mortality in goats and sheep and the disease has shown a greatly increased geographic distribution over the last 15 years.
Kehe Huang, Michael D Baron, Qianqian Hu, Weiye Chen, Zhigao Bu   +4 more
core   +1 more source

Lumpy Skin Disease Virus Infected Calves Showing Multisystemic Vasculitis on Postmortem Examination: A Summary of Six Cases

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
Lumpy skin disease (LSD) is a rapidly spreading transboundary viral disease of cattle and water buffalo that poses a significant threat to livestock health and economies of Bangladesh. Calf mortality is steadily increasing over time. This study documented fatal calf mortality with vasculitis‐driven multisystemic pathology, which has been rarely ...
Israt Jerin, Md. Riabbel Hossain, Shadia Tasnim, Seikh Masudur Rahman, Anja Globig, Bernd Hoffmann, Emdadul Haque Chowdhury, Rokshana Parvin, Zongfu Wu   +8 more
wiley   +1 more source

Detection of capripoxvirus DNA using a novel loop-mediated isothermal amplification assay [PDF]

BMC Veterinary Research, 2013
Abstract Background Sheep poxvirus (SPPV), Goat poxvirus (GTPV) and Lumpy skin disease virus (LSDV) are the most serious poxviruses of ruminants. They are double stranded DNA viruses of the genus Capripoxvirus, (subfamily Chordopoxvirinae) within the family Poxviridae.
Murray, Lee, Edwards, Lorraine, Tuppurainen, Eeva SM, Bachanek-Bankowska, Katarzyna, Oura, Chris AL, Mioulet, Valerie, King, Donald P   +6 more
openaire   +2 more sources

Epidemiological Study and Molecular Characterization of Lumpy Skin Disease in Cattle in Egypt

Veterinary Medicine International, Volume 2026, Issue 1, 2026.
Lumpy skin disease virus (LSDV) constitutes one of the most significant poxvirus infections impacting livestock and has a high morbidity rate and a comparatively low mortality rate. This study was designed to elucidate the epidemiology and the molecular analysis of LSDV using conventional polymerase chain reaction (PCR) to amplify the extracellular ...
Heba Hassan El-Nady, Ahmed Mansour, Mohamed Ibrahim Eissa, Naser Zeidan Abou-Zeid, Elshaima Mohamed Fawzi, Amal Mokhtar Abd El-Raof, Abdelrhman Awad Sobeih, Mohamed Mansour Bakrash, Yousry Abdelfatah El Shazly, Abdelfattah Selim   +9 more
wiley   +1 more source

THE APPROACHES TO DESIGNING OF NEW GENERATION VACCINES AGAINST THE SHEEP POX DISEASE [PDF]

Biotechnologia Acta, 2016
In this review the authors analyzed the sheep pox disease, which occurs outbreaks all over the world particularly in Asia and Africa causing substantial losses in trade of animal and animal products. They categorized the sheep pox disease is one of the
E. F. Yilmaz, P. P. Arayici, A. M. Maharramov , Z. Mustafaeva   +3 more
doaj   +1 more source

Differentiation of sheep poxvirus vaccines from field isolates and other Capripoxvirus species [PDF]

, 2018
Background The genus Capripoxvirus (CaPV) within the family Poxviridae com-prises three closely related viruses, sheep poxvirus (SPPV), goat poxvirus (GTPV) and lumpy skin disease virus (LSDV) causing sheep pox (SPP), goat pox (GTP) and lumpy skin ...
Berguido, Francisco, Cattoli, Giovanni, Chibssa, Tesfaye Rufael, Diallo, Adama, Euloge Lamien, Charles, Loitsch, Angelika, Settypalli, Tirumala Bharani Kumar   +6 more
core