Results 11 to 20 of about 71,965 (172)
Role of Genome in the Formation of Conical Retroviral Shells [PDF]
, 2016 Human immunodeficiency virus (HIV) capsid proteins spontaneously assemble around the genome into a protective protein shell called the capsid, which can take on a variety of shapes broadly classified as conical, cylindrical and irregular. The majority of
Erdemci-Tandogan, Gonca +3 more
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Catalytic capsids: the art of confinement [PDF]
Chem. Sci., 2011 In the cell, enzymes are almost always spatially confined in crowded and tightly controlled cellular compartments. The entrapment of enzymes in artificial nanoreactors as biomimetic systems can be expected to contribute to the understanding of the activity and the interactions of enzymes in confined spaces.
Minten, I.J. +6 more
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The Dynamic Life of Virus Capsids [PDF]
Viruses, 2020 Protein-shelled viruses have been thought as “tin cans” that merely carry the genomic cargo from cell to cell. However, through the years, it has become clear that viruses such as rhinoviruses and caliciviruses are active and dynamic structures waiting for the right environmental cues to deliver their genomic payload to the host cell.
Michael B. Sherman +2 more
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The Canadian Entomologist, 1903 Lygus Chagnoni, n. sp.— This species of the genus Lygus is of a form near to L. pabulinus, Linn., in appearance.It is ovate, convex bright green in living specimens, with irregular purplish-brown markings at the base of the membrane, smooth and without bristles, and a silky pubesecence on the sides of the pronotum, which has an orange-yellow border ...
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HIV Capsid and Integration Targeting [PDF]
Viruses, 2021 Integration of retroviral reverse transcripts into the chromosomes of the cells that they infect is required for efficient viral gene expression and the inheritance of viral genomes to daughter cells. Before integration can occur, retroviral reverse transcription complexes (RTCs) must access the nuclear environment where the chromosomes reside ...
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Proton-Linked Dimerization of a Retroviral Capsid Protein Initiates Capsid Assembly [PDF]
Structure, 2009 In mature retroviral particles, the capsid protein (CA) forms a shell encasing the viral replication complex. Human immunodeficiency virus (HIV) CA dimerizes in solution, through its C-terminal domain (CTD), and this interaction is important for capsid assembly.
Bailey, Graham +3 more
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Mechanical limits of viral capsids [PDF]
Proceedings of the National Academy of Sciences, 2007 We studied the elastic properties and mechanical stability of viral capsids under external force-loading with computer simulations. Our approach allows the implementation of specific geometries corresponding to specific phages, such as φ29 and cowpea chlorotic mottle virus.
Mathias Buenemann, Peter Lenz
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HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules [PDF]
Retrovirology, 2021 AbstractThe HIV-1 capsid, a conical shell encasing viral nucleoprotein complexes, is involved in multiple post-entry processes during viral replication. Many host factors can directly bind to the HIV-1 capsid protein (CA) and either promote or prevent HIV-1 infection.
Akatsuki Saito, Masahiro Yamashita
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The Canadian Entomologist, 1886 Lygus monachus, n. sp.Long oval, pale green or testaceous, coarsely punctate above, sericeous pubescent. Face convex, highly polished, bald; base of vertex with a longitudinal impressed line, towards which a similar line runs obliquely forward each side from the inner corner of the eye; antennæ sparsely and minutely pubescent; basal joint thickest, a ...
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The Dynamic Capsid Structures of the Noroviruses [PDF]
Viruses, 2019 Noroviruses are responsible for almost a fifth of all cases of gastroenteritis worldwide. New strains evolve every 2–4 years by escaping herd immunity and cause worldwide epidemics. In the US alone, noroviruses are responsible for ~20 million cases and more than 70,000 hospitalizations of infected children, annually. Efforts towards a vaccine have been
Hong Q. Smith, Thomas J. Smith
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