Results 31 to 40 of about 199,652 (304)

Assessment of the cross-protective capability of recombinant capsid proteins derived from pig, rat, and avian hepatitis E viruses (HEV) against challenge with a genotype 3 HEV in pigs [PDF]

open access: yes, 2012
Hepatitis E virus (HEV), the causative agent of hepatitis E, is primarily transmitted via the fecal-oral route through contaminated water supplies, although many sporadic cases of hepatitis E are transmitted zoonotically via direct contact with infected ...
Meng, Xiang-Jin   +5 more
core   +1 more source

Evidence of a Cellulosic Layer in Pandoravirus massiliensis Tegument and the Mystery of the Genetic Support of Its Biosynthesis

open access: yesFrontiers in Microbiology, 2019
Pandoraviruses are giant viruses of ameba with 1 μm-long virions. They have an ovoid morphology and are surrounded by a tegument-like structure lacking any capsid protein nor any gene encoding a capsid protein. In this work, we studied the ultrastructure
Djamal Brahim Belhaouari   +9 more
doaj   +1 more source

Rapidly Forming Early Intermediate Structures Dictate the Pathway of Capsid Assembly [PDF]

open access: yes, 2020
There are about 1030 possible intermediates on the assembly path from hepatitis B capsid protein dimers to the 120-dimer capsid. If every intermediate was tested, assembly would often get stuck in an entropic trap and essentially every capsid would ...
Uri, Raviv   +4 more
core   +1 more source

Hepatitis A Virus Capsid Structure [PDF]

open access: yesCold Spring Harbor Perspectives in Medicine, 2018
Hepatitis A virus (HAV) has been enigmatic, evading detailed structural analysis for many years. Its recently determined high-resolution structure revealed an angular surface without the indentations often characteristic of receptor-binding sites. The viral protein 1 (VP1) β-barrel shows no sign of a pocket factor and the amino terminus of VP2 displays
Stuart, D   +4 more
openaire   +3 more sources

Pharmacological Induction of Heme Oxygenase-1 Impairs Nuclear Accumulation of Herpes Simplex Virus Capsids upon Infection

open access: yesFrontiers in Microbiology, 2017
Heme oxygenase-1 (HO-1) is an inducible enzyme that is expressed in response to physical and chemical stresses, such as ultraviolet radiation, hyperthermia, hypoxia, reactive oxygen species (ROS), as well as cytokines, among others.
Francisco J. Ibáñez   +7 more
doaj   +1 more source

Genetic Code Expansion and Bio-Orthogonal Labeling Reveal Intact HIV-1 Capsids inside the Nucleus

open access: yesmBio, 2022
Microscopy is one of the few techniques that can directly observe the HIV-1 capsid as it traverses the cell. However, an extrinsic or intrinsic label is needed to facilitate detection and this can perturb capsid behavior. Now, S. Schifferdecker, V. Zila,
Leo C. James
doaj   +1 more source

Mechanical properties of viral capsids [PDF]

open access: yesPhysical Review E, 2005
12 ...
Zandi, Roya, Reguera, D. (David)
openaire   +4 more sources

Bacteriophages and their structural organisation [PDF]

open access: yes, 2012
Viruses are extremely small infectious particles that are not visible in a light microscope, and are able to pass through fine porcelain filters. They exist in a huge variety of forms and infect practically all living systems: animals, plants ...
E.V. Orlova, Orlova, Elena
core   +2 more sources

UL25 capsid binding facilitates mechanical maturation of the Herpesvirus capsid and allows retention of pressurized DNA [PDF]

open access: yes, 2021
The maturation process that occurs in most viruses is evolutionarily driven as it resolves several conflicting virion assembly requirements. During herpesvirus assembly in a host cell nucleus, micron-long double-stranded herpes DNA is packaged into a ...
Homa, Fred L   +3 more
core   +1 more source

HIV-1 capsid variability: viral exploitation and evasion of capsid-binding molecules [PDF]

open access: yesRetrovirology, 2021
AbstractThe HIV-1 capsid, a conical shell encasing viral nucleoprotein complexes, is involved in multiple post-entry processes during viral replication. Many host factors can directly bind to the HIV-1 capsid protein (CA) and either promote or prevent HIV-1 infection.
Akatsuki Saito, Masahiro Yamashita
openaire   +4 more sources

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