Results 51 to 60 of about 249,247 (291)

Density waves theory of the capsid structure of small icosahedral viruses

, 2006
We apply Landau theory of crystallization to explain and to classify the capsid structures of small viruses with spherical topology and icosahedral symmetry.
D. L. D. Caspar, J. B. Bancroft, J. P. Elliot, L. D. Landau, L. D. Landau, S. B. Rochal, S. J. Flint, T. S. Baker, V. L. Lorman   +8 more
core   +3 more sources

A Vibrio cholerae viral satellite maximizes its spread and inhibits phage by remodeling hijacked phage coat proteins into small capsids

eLife
Phage satellites commonly remodel capsids they hijack from the phages they parasitize, but only a few mechanisms regulating the change in capsid size have been reported.
Caroline M Boyd, Sundharraman Subramanian, Drew T Dunham, Kristin N Parent, Kimberley D Seed   +4 more
doaj   +1 more source

Phylogeny and Immunoreactivity of Norovirus GII.P16-GII.2, Japan, Winter 2016–17

Emerging Infectious Diseases, 2018
During the 2016–17 winter season in Japan, human norovirus GII.P16-GII.2 strains (2016 strains) caused large outbreaks of acute gastroenteritis. Phylogenetic analyses suggested that the 2016 strains derived from the GII.2 strains detected during 2010–12.
Koo Nagasawa, Yuki Matsushima, Takumi Motoya, Fuminori Mizukoshi, Yo Ueki, Naomi Sakon, Koichi Murakami, Tomomi Shimizu, Nobuhiko Okabe, Noriko Nagata, Komei Shirabe, Hiroto Shinomiya, Wataru Suzuki, Makoto Kuroda, Tsuyoshi Sekizuka, Akihide Ryo, Kiyotaka Fujita, Kazunori Oishi, Kazuhiko Katayama, Hirokazu Kimura   +19 more
doaj   +1 more source

Structural Analysis of Retrovirus Assembly and Maturation

Viruses, 2021
Retroviruses have a very complex and tightly controlled life cycle which has been studied intensely for decades. After a virus enters the cell, it reverse-transcribes its genome, which is then integrated into the host genome, and subsequently all ...
Anna-Sophia Krebs, Luiza M. Mendonça, Peijun Zhang   +2 more
doaj   +1 more source

Dynamics of polymer ejection from capsid

, 2014
Polymer ejection from a capsid through a nanoscale pore is an important biological process with relevance to modern biotechnology. Here, we study generic capsid ejection using Langevin dynamics.
Kaski, K., Linna, R. P., Moisio, J. E., Suhonen, P. M.   +3 more
core   +1 more source

Viral self-assembly as a thermodynamic process [PDF]

, 2003
The protein shells, or capsids, of all sphere-like viruses adopt icosahedral symmetry. In the present paper we propose a statistical thermodynamic model for viral self-assembly.
Bruinsma, Robijn F., Gelbart, William M., Reguera, David, Rudnick, Joseph, Zandi, Roya   +4 more
core   +3 more sources

Mapping the Cerebral Organoid Landscape: A Systematic Review of Preclinical 3D Models in Neuroscience

Advanced Healthcare Materials, EarlyView.
Cerebral organoids are transforming brain research, yet the field remains fragmented. This comprehensive systematic review maps 738 studies published between 2014 and 2024 to uncover trends, gaps, and opportunities across neuroscience. Introducing OrganoidMap—an interactive, open‐access platform to explore and compare models—this work enables ...
Anna Wolfram, Vanessa Arnold, Maik Wolfram‐Schauerte, Anastassiya Moskalchuk, Caroline Trust, Marie Vontz, Mona Scheurenbrand, Vijayasarathy Sampath‐Kumar, Sogand Ahari, Carlos Romero‐Nieto, Lisa Sevenich   +10 more
wiley   +1 more source

Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration

mBio
Human immunodeficiency virus type 1 (HIV-1) capsid, which is the target of the antiviral lenacapavir, protects the viral genome and binds multiple host proteins to influence intracellular trafficking, nuclear import, and integration.
Zachary Ingram, Christopher Kline, Alexandra K. Hughson, Parmit K. Singh, Hannah L. Fischer, Rajalingham Radhakrishnan, Gregory A. Sowd, Nayara F. B. Dos Santos, Barbie K. Ganser-Pornillos, Simon C. Watkins, Melissa Kane, Alan N. Engelman, Zandrea Ambrose   +12 more
doaj   +1 more source

HIV Capsid Inhibitors Beyond PF74

Diseases, 2019
Human immunodeficiency virus (HIV) capsid plays important roles at multiple stages of viral replication. At the initial stages, controlled uncoating (disassembly) of the capsid ensures efficient reverse transcription of the single-stranded RNA genome ...
Carole McArthur, Fabio Gallazzi, Thomas P. Quinn, Kamal Singh   +3 more
doaj   +1 more source

Biomimetic Copper Nanoparticles Coated with ACE2‐Overexpressing Membranes for Selective SARS‐CoV‐2 Neutralization and Disinfection

Advanced Healthcare Materials, EarlyView.
By fusing ACE2‐overexpressing membrane‐integrated liposome (MIL) with copper nanoparticles, the biomimetic Cu@MIL nanostructures were created that directly hijack the SARS‐CoV‐2 entry pathway. These particles combine potent virus‐targeting precision with intrinsic antiviral activity, achieving rapid neutralization and disinfection.
Pooja Aich, Wei‐Pang Chung, Wen‐Jyun Wang, Hidenobu Takahashi, Ming‐Shun Hsieh, Ying‐Chen Lin, Oh Seok Kwon, Wei‐Peng Li, Wei‐Lun Huang   +8 more
wiley   +1 more source