Results 51 to 60 of about 214,858 (192)
Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold
mBio, 2017 Large icosahedral viruses that infect bacteria represent an extreme of the coevolution of capsids and the genomes they accommodate. One subset of these large viruses is the jumbophages, tailed phages with double-stranded DNA genomes of at least 200,000 ...
Jianfei Hua +7 more
doaj +1 more source
Mechanical properties of viral capsids [PDF]
Physical Review E, 2005 12 ...
Zandi, Roya, Reguera, D. (David)
openaire +4 more sources
A Protein-Capsid-Based System for Cell Delivery of Selenocysteine
, 2018 Selenocysteine (Sec) has received a lot of attention as a potential anticancer drug. However, its broad cytotoxicity limits its therapeutic usefulness. Thus, Sec is an attractive candidate for targeted drug delivery.
Kenneth J. Woycechowsky (2054407) +4 more
core +1 more source
The DNA Ejection Process in Bacteriophage λ [PDF]
, 2007 Bacteriophages have long served as model systems through which the nature of life may be explored. From a physical or mechanical point of view, phages are excellent examples of natural nanotechnology: they are nanometer-scale systems which depend ...
Grayson, Paul Daniel
core +1 more source
Molecular Therapy: Methods & Clinical Development, 2022 Prescreening of participants in clinical trials that use adeno-associated virus (AAV) vectors is required to identify naive participants, as preexisting neutralizing antibodies can limit the efficacy of AAV gene therapies.
Matthew R. Gardner +6 more
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Hepatitis A Virus Capsid Structure [PDF]
Cold Spring Harbor Perspectives in Medicine, 2018 Hepatitis A virus (HAV) has been enigmatic, evading detailed structural analysis for many years. Its recently determined high-resolution structure revealed an angular surface without the indentations often characteristic of receptor-binding sites. The viral protein 1 (VP1) β-barrel shows no sign of a pocket factor and the amino terminus of VP2 displays
Stuart, D +4 more
openaire +3 more sources
A tail-like assembly at the portal vertex in intact herpes simplex type-1 virions [PDF]
, 2012 Herpes viruses are prevalent and well characterized human pathogens. Despite extensive study, much remains to be learned about the structure of the genome packaging and release machinery in the capsids of these large and complex double-stranded DNA ...
Rixon Frazer J. +23 more
core +1 more source
eLifePhage satellites commonly remodel capsids they hijack from the phages they parasitize, but only a few mechanisms regulating the change in capsid size have been reported.
Caroline M Boyd +4 more
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Viruses, 2020 Capsid-like particles (CLPs) are multimeric, repetitive assemblies of recombinant viral capsid proteins, which are highly immunogenic due to their structural similarity to wild-type viruses.
Kara-Lee Aves +2 more
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Interplay between Host tRNAs and HIV-1: A Structural Perspective
Viruses, 2021 The cellular metabolism of host tRNAs and life cycle of HIV-1 cross paths at several key virus–host interfaces. Emerging data suggest a multi-faceted interplay between host tRNAs and HIV-1 that plays essential roles, both structural and regulatory, in ...
Jinwei Zhang
doaj +1 more source