Results 61 to 70 of about 214,858 (192)
mBioHuman immunodeficiency virus type 1 (HIV-1) capsid, which is the target of the antiviral lenacapavir, protects the viral genome and binds multiple host proteins to influence intracellular trafficking, nuclear import, and integration.
Zachary Ingram +12 more
doaj +1 more source
Advances in Recombinant Adeno-Associated Virus Vectors for Neurodegenerative Diseases
Biomedicines, 2023 Recombinant adeno-associated virus (rAAV) vectors are gene therapy delivery tools that offer a promising platform for the treatment of neurodegenerative diseases. Keeping up with developments in this fast-moving area of research is a challenge.
Leyao Li +11 more
doaj +1 more source
A novel platform for engineered AAV-based vaccines
Molecular Therapy: Methods & Clinical DevelopmentEngineering of adeno-associated virus (AAV) capsids allowed for the development of gene therapy vectors with improved tropism and enhanced transduction efficiency.
Sabrina Babutzka +12 more
doaj +1 more source
Overlap Intensity: An ImageJ Macro for Analyzing the HIV-1 In Situ Uncoating Assay
Viruses, 2021 Capsid uncoating is at the crossroads of early steps in HIV-1 replication. In recent years, the development of novel assays has expanded how HIV-1 uncoating can be studied.
Zachary Ingram +4 more
doaj +1 more source
Capsid and vector genome copy quantification.
, 2021 Capsid and vector genome copy quantification using ELISA and qPCR, respectively. Ratio between capsid and genomic titer is shown. (DOCX)
Carola Schneider (3743791) +11 more
core +1 more source
Phylogeny and Immunoreactivity of Norovirus GII.P16-GII.2, Japan, Winter 2016–17
Emerging Infectious Diseases, 2018 During the 2016–17 winter season in Japan, human norovirus GII.P16-GII.2 strains (2016 strains) caused large outbreaks of acute gastroenteritis. Phylogenetic analyses suggested that the 2016 strains derived from the GII.2 strains detected during 2010–12.
Koo Nagasawa +19 more
doaj +1 more source
Structural Analysis of Retrovirus Assembly and Maturation
Viruses, 2021 Retroviruses have a very complex and tightly controlled life cycle which has been studied intensely for decades. After a virus enters the cell, it reverse-transcribes its genome, which is then integrated into the host genome, and subsequently all ...
Anna-Sophia Krebs +2 more
doaj +1 more source
HIV Capsid Inhibitors Beyond PF74
Diseases, 2019 Human immunodeficiency virus (HIV) capsid plays important roles at multiple stages of viral replication. At the initial stages, controlled uncoating (disassembly) of the capsid ensures efficient reverse transcription of the single-stranded RNA genome ...
Carole McArthur +3 more
doaj +1 more source
Use of Capsid Integrity-qPCR for Detecting Viral Capsid Integrity in Wastewater
Viruses, 2023 Quantifying viruses in wastewater via RT-qPCR provides total genomic data but does not indicate the virus capsid integrity or the potential risk for human infection. Assessing virus capsid integrity in sewage is important for wastewater-based surveillance, since discharged effluent may pose a public health hazard.
Jessica L. Kevill +5 more
openaire +3 more sources
The Canadian Entomologist, 1886 Lygus monachus, n. sp.Long oval, pale green or testaceous, coarsely punctate above, sericeous pubescent. Face convex, highly polished, bald; base of vertex with a longitudinal impressed line, towards which a similar line runs obliquely forward each side from the inner corner of the eye; antennæ sparsely and minutely pubescent; basal joint thickest, a ...
openaire +2 more sources