Results 41 to 50 of about 199,652 (304)

The DNA Ejection Process in Bacteriophage λ [PDF]

, 2007
Bacteriophages have long served as model systems through which the nature of life may be explored. From a physical or mechanical point of view, phages are excellent examples of natural nanotechnology: they are nanometer-scale systems which depend ...
Grayson, Paul Daniel
core   +1 more source

HIV-1 Capsid Core: A Bullet to the Heart of the Target Cell

Frontiers in Microbiology, 2021
The first step of the intracellular phase of retroviral infection is the release of the viral capsid core in the cytoplasm. This structure contains the viral genetic material that will be reverse transcribed and integrated into the genome of infected ...
Elenia Toccafondi, Daniela Lener, Matteo Negroni   +2 more
doaj   +1 more source

Use of Capsid Integrity-qPCR for Detecting Viral Capsid Integrity in Wastewater

Viruses, 2023
Quantifying viruses in wastewater via RT-qPCR provides total genomic data but does not indicate the virus capsid integrity or the potential risk for human infection. Assessing virus capsid integrity in sewage is important for wastewater-based surveillance, since discharged effluent may pose a public health hazard.
Jessica L. Kevill, Kata Farkas, Nicola Ridding, Nicholas Woodhall, Shelagh K. Malham, Davey L. Jones   +5 more
openaire   +3 more sources

Cluster J Mycobacteriophages: Intron Splicing in Capsid and Tail Genes [PDF]

, 2013
Bacteriophages isolated on Mycobacterium smegmatis mc2155 represent many distinct genomes sharing little or no DNA sequence similarity. The genomes are architecturally mosaic and are replete with genes of unknown function.
Susan Offner, Thibault, Sarah A, Deborah Jacobs-Sera, Aaron A Best, Best, AA, Welkin H Pope, Conway, JF, Daniel A. Russell (199599), Deborah Jacobs-Sera (199566), Emily L. Stowe (431712), Stukey, Joseph, Rebekah M Dedrick, Broussard, GW, Russell, Daniel A, Offner, Susan, Marie C Pizzorno, Emily L Stowe, Pamela L. Connerly (431705), Marie C. Pizzorno (431710), Kremer, Timothy A, Conway, James F, Aaron A. Best (231720), Graham F Hatfull, Gregory W. Broussard (431704), Jacobs-Sera, Deborah, Graham F. Hatfull (174881), Connerly, PL, Kremer, TA, Connerly, Pamela L, Welkin H. Pope (199562), Hatfull, GF, Stowe, EL, Pope, Welkin H, Hendrix, Roger W, Stowe, Emily L, Best, Aaron A, Sarah A. Thibault (431713), Rebekah M. Dedrick (431706), Sarah A Thibault, James F Conway, Rockenbach, Kate, Gregory W Broussard, James F. Conway (393058), Jacobs-Sera, D, Hatfull, Graham F., Joseph Stukey, Dedrick, Rebekah M, Pamela L Connerly, Roger W Hendrix, Joseph Stukey (232098), Ogiefo, AH, Amenawon H. Ogiefo (431709), Kate Rockenbach, Susan Offner (431708), Ogiefo, Amenawon H, Daniel A Russell, Dedrick, RM, Stukey, J, Timothy A Kremer, Rockenbach, K, Amenawon H Ogiefo, Kate Rockenbach (431711), Pizzorno, Marie, Hendrix, RW, Pope, WH, Russell, DA, Broussard, Gregory W, Roger W. Hendrix (199647), Rochenbach, Kate, Pizzorno, Marie C, Offner, S, Thibault, SA, Timothy A. Kremer (431707), Pizzorno, MC, Hatfull, Graham F   +74 more
core   +1 more source

Structural and dynamics investigations of HIV-1 capsid and its interactions with cyclophilin A: atomic-level insights from magic angle spinning NMR [PDF]

, 2022
Polenova, TatyanaIn a mature HIV-1 virion, the viral capsid (CA) protein assembles into a conical capsid, enclosing the viral genome and viral proteins.
Lu, Manman
core   +1 more source

Characterisation of a non-pathogenic and non-protective infectious rabbit lagovirus related to RHDV [PDF]

, 2010
The existence of non-pathogenic RHDV strains was established when a non-lethal virus named rabbit calicivirus (RCV) was characterised in 1996 in Italy.
Le Gall-Reculé, Ghislaine, Lavazza, Antonio, Roobrouck , Alain, Ghislaine Le Gall-Reculé, Stéphane Bertagnoli, Jacky Aubineau, Antonio Lavazza, Zwingelstein, Françoise, Giuliana Botti, Bertagnoli, Stéphane, Stéphane Marchandeau, Marie-Philippe Fages, Jacqueline Gelfi, Fages, Marie-Philippe, Gelfi, Jacqueline, Botti, Giuliana, Françoise Zwingelstein, Alain Roobrouck, Roobrouck, Alain, Aubineau, Jacky, Marchandeau, Stéphane   +20 more
core   +1 more source

Host-driven evolution of PCV2: insights into genetic diversity and adaptation

Frontiers in Immunology
IntroductionsPorcine circovirus type 2 (PCV2) is a significant pathogen in swine, exhibiting notable genetic and phenotypic diversity. This study explores the evolutionary mechanisms influencing PCV2 variability, emphasizing the role of viral features ...
Giovanni Franzo, Matteo Legnardi, Francesca Poletto, Riccardo Baston, Mattia Cecchinato, Michele Drigo, Claudia Maria Tucciarone   +6 more
doaj   +1 more source

The In Silico Prediction of Hotspot Residues that Contribute to the Structural Stability of Subunit Interfaces of a Picornavirus Capsid

Viruses, 2020
The assembly of picornavirus capsids proceeds through the stepwise oligomerization of capsid protein subunits and depends on interactions between critical residues known as hotspots.
Nicole Upfold, Caroline Ross, Özlem Tastan Bishop, Caroline Knox   +3 more
doaj   +1 more source

Reconstituted virus–nucleus system reveals mechanics of herpesvirus genome uncoating

QRB Discovery, 2022
The viral replication cycle is controlled by information transduced through both molecular and mechanical interactions. Viral infection mechanics remains largely unexplored, however, due to the complexity of cellular mechanical responses over the course ...
Alex Evilevitch, Efthymios Tsimtsirakis
doaj   +1 more source

Self-Assembly of Fluorescent HIV Capsid Spheres for Detection of Capsid Binders

Langmuir, 2020
The human immunodeficiency virus (HIV) capsid is a cone-shaped capsule formed from the viral capsid protein (CA), which is arranged into a lattice of hexamers and pentamers. The capsid comprises multiple binding interfaces for the recruitment of host proteins and macromolecules used by the virus to establish infection.
Lau, D, Walsh, JC, Mousapasandi, A, Ariotti, N, Shah, VB, Turville, S, Jacques, DA, Böcking, T   +7 more
openaire   +5 more sources