Results 41 to 50 of about 249,247 (291)
Interplay between Host tRNAs and HIV-1: A Structural Perspective
Viruses, 2021 The cellular metabolism of host tRNAs and life cycle of HIV-1 cross paths at several key virus–host interfaces. Emerging data suggest a multi-faceted interplay between host tRNAs and HIV-1 that plays essential roles, both structural and regulatory, in ...
Jinwei Zhang
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Dynamics of Bacteriophage Genome Ejection In Vitro and In Vivo
, 2010 Bacteriophages, phages for short, are viruses of bacteria. The majority of phages contain a double-stranded DNA genome packaged in a capsid at a density of ~500 mg/ml. This high density requires substantial compression of the normal B form helix, leading
Molineux, Ian J., Panja, Debabrata
core +1 more source
Bionanomaterials from plant viruses [PDF]
, 2015 Plant virus capsids have emerged as useful biotemplates for material synthesis. All plant virus capsids are assembled with high-precision, three-dimensional structures providing nanoscale architectures that are highly monodisperse, can be produced in ...
Aljabali, Alaa A. A., Evans, David
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Capsids and Genomes of Jumbo-Sized Bacteriophages Reveal the Evolutionary Reach of the HK97 Fold
mBio, 2017 Large icosahedral viruses that infect bacteria represent an extreme of the coevolution of capsids and the genomes they accommodate. One subset of these large viruses is the jumbophages, tailed phages with double-stranded DNA genomes of at least 200,000 ...
Jianfei Hua +7 more
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Advances in Recombinant Adeno-Associated Virus Vectors for Neurodegenerative Diseases
Biomedicines, 2023 Recombinant adeno-associated virus (rAAV) vectors are gene therapy delivery tools that offer a promising platform for the treatment of neurodegenerative diseases. Keeping up with developments in this fast-moving area of research is a challenge.
Leyao Li +11 more
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Statistical analysis of sizes and shapes of virus capsids and their resulting elastic properties
, 2013 From the analysis of sizes of approximately 130 small icosahedral viruses we find that there is a typical structural capsid protein, having a mean diameter of 5 nm and a mean thickness of 3 nm, with more than two thirds of the analyzed capsid proteins ...
Bozic, Anze Losdorfer +2 more
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Dengue Virus Genome Uncoating Requires Ubiquitination [PDF]
, 2016 The process of genome release or uncoating after viral entry is one of the least-studied steps in the flavivirus life cycle. Flaviviruses are mainly arthropod-borne viruses, including emerging and reemerging pathogens such as dengue, Zika, and West Nile ...
Byk, Laura Andrea +5 more
core +3 more sources
A beta-herpesvirus with fluorescent capsids to study transport in living cells. [PDF]
, 2012 Fluorescent tagging of viral particles by genetic means enables the study of virus dynamics in living cells. However, the study of beta-herpesvirus entry and morphogenesis by this method is currently limited.
Bauerfeind, Rudolf +11 more
core +9 more sources
mBioHIV-1 viral core transport to the nucleus, an early infection event, triggers the redistribution of cleavage and polyadenylation specificity factors (CPSF) 5 and CPSF6 to nuclear speckles, forming puncta-like structures.
Charlotte Luchsinger +9 more
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Overlap Intensity: An ImageJ Macro for Analyzing the HIV-1 In Situ Uncoating Assay
Viruses, 2021 Capsid uncoating is at the crossroads of early steps in HIV-1 replication. In recent years, the development of novel assays has expanded how HIV-1 uncoating can be studied.
Zachary Ingram +4 more
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