Results 191 to 200 of about 31,732 (250)

Protein Nanocages as Versatile Vectors for Nucleic Acid Delivery: Main Systems and Their Loading Mechanisms. [PDF]

Mol Biotechnol
Coffeen CF, Hernández-Gutiérrez AE, Bustos-Jaimes I.   +2 more
europepmc   +1 more source

Identification Epitope on VP4 Protein of Senecavirus A Recognized by a Monoclonal Antibody

Animal Research and One Health, Volume 4, Issue 3, Page 293-301, August 2026.
This study aims to identify conserved antigenic epitopes on the SVA VP4 protein using monoclonal antibodies, providing valuable tools for further exploring its functions and developing detection methods. SVA VP4 protein was expressed in Escherichia coli and purified with High‐Affinity Ni‐Charged Resin FF.
Liang Meng, Xuyan Xiang, Xinyu Qi, Hanrong Zhou, Peiyu Xiao, Fandan Meng, Tongqing An, Haiwei Wang   +7 more
wiley   +1 more source

Oral immunization with recombinant Lactococcus lactis expressing VP3 and VP3-IFNα fusion protein protects ducklings against novel goose parvovirus infection. [PDF]

Poult Sci
Yang J, Wei F, He D, Liu G, Yan Y, Peng P, Zhou J, Zhang Y, Diao Y, Diao Y.   +9 more
europepmc   +1 more source

Anion‐Exchange Membrane Chromatography for the Separation of Empty and Full Adeno‐Associated Viral Capsids

Biotechnology Journal, Volume 21, Issue 8, August 2026.
Graphical Abstract and Lay Summary The anion‐exchange membrane elution chromatography for the separation of empty and full AAVs is explored and optimized. The role played by important parameters like flowrate, gradient slope, membrane loading, and feed residence time is studied in detail.
Luca Ossi, Samuele Delfino, Helena Marie, Michael Schulte, Mattia Sponchioni   +4 more
wiley   +1 more source

Structural Remodeling of Phage φPNJ-6 Hoc Promotes Adhesion to the Intestinal Epithelium. [PDF]

Transbound Emerg Dis
Ye L, Wang X, Cui J, Chen X, Tao P, Liu Y, Zhang Y, Xue F, Dai J, Tang F.   +9 more
europepmc   +1 more source

Deep Mutational Scanning for the Study and Engineering of Protein Assemblies

Chemistry–Methods, Volume 6, Issue 8, August 2026.
This review explores how deep mutational scanning (DMS) can be used to improve understanding and accelerate engineering of protein assemblies, from natural fibers to engineered nanocages. We discuss various types of protein assemblies and their characterization, provide an introduction to the DMS technique, and then highlight examples in which DMS has ...
Jenna B. Wolfanger, Shoili Banerjee, Carolyn E. Mills   +2 more
wiley   +1 more source

Genetically Encoded SpyTag Enables Modular AAV Retargeting via SpyCatcher-Fused Ligands for Targeted Gene Delivery. [PDF]

ACS Synth Biol
Armbruster A, Hörner M, Wagner HJ, Fink-Straube C, Weber W.   +4 more
europepmc   +1 more source

Active Vaccination Strategies for Alzheimer's Disease: An Expanded Review

European Journal of Immunology, Volume 56, Issue 8, August 2026.
Overview of immunotherapeutic strategies targeting Alzheimer's disease (AD) pathology and their clinical implications. (Left) Key neuropathological hallmarks of AD, including extracellular amyloid‐beta (Aβ) aggregates and intraneuronal hyperphosphorylated Tau (phospho‐Tau), converge to produce synaptic failure, neuroinflammation and neuronal ...
Antonella Comitato, Antonino Neri, Andrea Cossarizza   +2 more
wiley   +1 more source

Deep-sequencing-guided library screening and profiling of AAV capsids in the primate retina. [PDF]

Mol Ther Adv
Fouani Y, Blazevic D, Oti M, Becker R, Strobel B, Schönberger T, Stephan M, Wichert S, Reichel FF, Seitz IP, Korbmacher B, Achberger K, Roosz J, Loskill P, Maier U, Michelfelder S, Schön C.   +16 more
europepmc   +1 more source

Successful Treatment of Adult Epstein–Barr Virus‐Associated Hemophagocytic Lymphohistiocytosis With Etoposide Guided by Plasma Epstein–Barr Virus DNA Monitoring: A Case Report

eJHaem, Volume 7, Issue 4, August 2026.
ABSTRACT Hemophagocytic lymphohistiocytosis (HLH) is a life‐threatening hyperinflammatory syndrome. Epstein–Barr virus (EBV)‐associated HLH is a major subtype of secondary HLH, requiring prompt diagnosis and treatment. However, treatment is particularly challenging in patients with severe coagulopathy and hepatic dysfunction.
Kuniaki Maehara, Masuho Saburi, Katsuya Kawano, Takahiro Kusaba, Shogo Urabe, Eiichi Ohtsuka   +5 more
wiley   +1 more source