Results 1 to 10 of about 1,206,877 (302)

Towards rational computational peptide design

open access: yesFrontiers in Bioinformatics, 2022
Peptides are prevalent in biology, mediating as many as 40% of protein-protein interactions, and involved in other cellular functions such as transport and signaling.
Liwei Chang   +5 more
doaj   +3 more sources

Digital Model and Assembling of a Lathe [PDF]

open access: yesЖурнал інженерних наук, 2022
The article aims at developing a digital model of a lathe and the related technology for its assembling. The study is based on analyzing the service purpose and technological capabilities of modern modular machine tools, justification and development of ...
Besedin M.   +3 more
doaj   +1 more source

Scenario-based mission statements

open access: yesTATuP – Zeitschrift für Technikfolgenabschätzung in Theorie und Praxis, 2021
Using a planning process for the Stuttgart Neckar Valley as a case study, this paper analyzes the urban inertial forces that counteract the transformation of energy infrastructure areas in the context of the energy transition.
Raphael Dietz   +5 more
doaj   +1 more source

Rational formulation design [PDF]

open access: yesInternational Journal of Cosmetic Science, 2012
SynopsisTo be efficacious and to satisfy the requirements for claim substantiation, a cosmetic formulation must achieve effective targeting of an active in the skin. Although the basic principles governing the skin permeation and disposition of molecules have been known for many years, attention has been far less focused on the role of the vehicle ...
M E, Lane   +5 more
openaire   +2 more sources

Diversity of Self-Assembled RNA Complexes: From Nanoarchitecture to Nanomachines

open access: yesMolecules, 2023
New tool development for various nucleic acid applications is an essential task in RNA nanotechnology. Here, we determined the ability of self-limited complex formation by a pair of oligoribonucleotides carrying two pairwise complementary blocks ...
Maria A. Kanarskaya   +2 more
doaj   +1 more source

Rationally designed tularemia vaccines [PDF]

open access: yesExpert Review of Vaccines, 2009
Tularemia, caused by the Gram-negative bacterium Francisella tularensis, can be contracted by the bite of an arthropod vector or by inhalation. This disease occurs relatively infrequently but can be severe and even life-threatening if untreated. Until recently, there were few laboratories studying this organism; however, concerns over its potential use
Barbara J, Mann, Nicole M, Ark
openaire   +2 more sources

Rational Design of Atomically Dispersed Metal Site Electrocatalysts for Oxygen Reduction Reaction

open access: yesAdvanced Science, 2023
Future renewable energy supply and a cleaner Earth greatly depend on various crucial catalytic reactions for the society. Atomically dispersed metal site electrocatalysts (ADMSEs) have attracted tremendous research interest and are considered as the next‐
Kechuang Wan   +4 more
doaj   +1 more source

Illuminating the Effect of the Local Environment on the Performance of Organic Sunscreens: Insights From Laser Spectroscopy of Isolated Molecules and Complexes

open access: yesFrontiers in Chemistry, 2022
Sunscreens are essential for protecting the skin from UV radiation, but significant questions remain about the fundamental molecular-level processes by which they operate. In this mini review, we provide an overview of recent advanced laser spectroscopic
Natalie G. K. Wong   +1 more
doaj   +1 more source

Rational Design of Inland Water Vessels [PDF]

open access: yesPort Said Engineering Research Journal, 2019
This paper has demonstrated the design aspects for inland water units working in the River Nile. The acting loads and stresses induced in the structural elements of inland units are still water bending moment and stresses, local hydrostatic pressure and ...
Mohamed Shamah   +2 more
doaj   +1 more source

Rationally Designed Bicyclic Peptides Prevent the Conversion of Aβ42 Assemblies Into Fibrillar Structures

open access: yesFrontiers in Neuroscience, 2021
There is great interest in drug discovery programs targeted at the aggregation of the 42-residue form of the amyloid β peptide (Aβ42), since this molecular process is closely associated with Alzheimer’s disease.
Tatsuya Ikenoue   +4 more
doaj   +1 more source

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