Results 21 to 30 of about 1,206,877 (302)

Parallel Strategy Increases the Thermostability and Activity of Glutamate Decarboxylase

open access: yesMolecules, 2020
Glutamate decarboxylase (GAD; EC 4.1.1.15) is a unique pyridoxal 5-phosphate (PLP)-dependent enzyme that specifically catalyzes the decarboxylation of L-glutamic acid to produce γ-aminobutyric acid (GABA), which exhibits several well-known ...
Qing-Fei Zhang   +5 more
doaj   +1 more source

Development and Application of Transcription Terminators for Polyhydroxylkanoates Production in Halophilic Halomonas bluephagenesis TD01

open access: yesFrontiers in Microbiology, 2022
Halomonas bluephagenesis TD01 is one of the ideal chassis for low-cost industrial production based on “Next Generation Industrial Biotechnology,” yet the limited genetically regulatory parts such as transcriptional terminators, which are crucial for ...
Mengmeng Xu   +7 more
doaj   +1 more source

Optimal designs for a class of nonlinear regression models [PDF]

open access: yes, 2004
For a broad class of nonlinear regression models we investigate the local E- and c-optimal design problem. It is demonstrated that in many cases the optimal designs with respect to these optimality criteria are supported at the Chebyshev points, which ...
Dette, Holger   +2 more
core   +2 more sources

Rational designs

open access: yesAdvances in Mathematics, 2019
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Cui, Zhen, Xia, Jiacheng, Xiang, Ziqing
openaire   +2 more sources

Rational Design of Multifunctional Ferulic Acid Derivatives Aimed for Alzheimer’s and Parkinson’s Diseases

open access: yesAntioxidants, 2023
Ferulic acid has numerous beneficial effects on human health, which are frequently attributed to its antioxidant behavior. In this report, many of them are reviewed, and 185 new ferulic acid derivatives are computationally designed using the CADMA-Chem ...
Eduardo Gabriel Guzmán-López   +3 more
doaj   +1 more source

Rational design of super-alkalis and their role in CO2 activation [PDF]

open access: yes, 2017
Super-alkalis are clusters of atoms. With ionization potentials smaller than those of the alkali atoms, they are playing an increasing role in chemistry as highlighted by recent applications in solar cells as well as in Li-ion batteries.
Jena, Puru, Wang, Qian, Zhao, Tianshan
core   +3 more sources

Heterologous Expression and Rational Design of l-asparaginase from Rhizomucor miehei to Improve Thermostability

open access: yesBiology, 2021
l-asparaginase (EC 3.5.1.1) hydrolyzes l-asparagine to produce l-aspartate and ammonia and is widely found in microorganisms, plants, and some rodent sera. l-asparaginase used for industrial production should have good thermostability.
Xian Zhang   +8 more
doaj   +1 more source

Efficient design optimization of complex electromagnetic systems using parametric macromodeling techniques [PDF]

open access: yes, 2011
We propose a new parametric macromodeling technique for complex electromagnetic systems described by scattering parameters, which are parameterized by multiple design variables such as layout or substrate feature.
Antonini, Giulio   +4 more
core   +2 more sources

Current state of molecular and metabolic strategies for the improvement of L-asparaginase expression in heterologous systems

open access: yesFrontiers in Pharmacology, 2023
Heterologous expression of L-asparaginase (L-ASNase) has become an important area of research due to its clinical and food industry applications. This review provides a comprehensive overview of the molecular and metabolic strategies that can be used to ...
Nicolás Lefin   +7 more
doaj   +1 more source

Optimizing rational vaccine design [PDF]

open access: yesMicrobial Biotechnology, 2009
Vaccines are the most cost‐efficient tool to prevent infectious diseases, and their therapeutic use, against both infectious and non‐infectious (e.g. cancer, autoimmunity) diseases, is gaining considerable interest. However, despite major advances in the fields of microbial pathogenesis, immunology and vaccinology, there are still many diseases for ...
openaire   +2 more sources

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