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Arthritogenic Alphavirus Capsid Protein
Life, 2021 In the past two decades Old World and arthritogenic alphavirus have been responsible for epidemics of polyarthritis, causing high morbidity and becoming a major public health concern. The multifunctional arthritogenic alphavirus capsid protein is crucial
Shambhavi Rao, Adam Taylor
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Structure of the herpesvirus major capsid protein [PDF]
The EMBO Journal, 2003 Herpes simplex virus-1 (HSV-1) virions are large, complex enveloped particles containing a proteinaceous tegument layer connected to an icosahedral capsid. The major capsid protein, VP5 (149 kDa), makes up both types of capsomere, pentons and hexons. Limited trypsin digestion of VP5 identified a single stable 65 kDa fragment which represents a proposed
Brian R. Bowman
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The Alphaviral Capsid Protein Inhibits IRAK1-Dependent TLR Signaling
Viruses, 2021 Alphaviruses are arthropod-borne RNA viruses which can cause either mild to severe febrile arthritis which may persist for months, or encephalitis which can lead to death or lifelong cognitive impairments.
V. Douglas Landers +4 more
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Stimulation of dendritic cell functional maturation by capsid protein from chikungunya virus [PDF]
Iranian Journal of Basic Medical Sciences, 2020 Objective(s): Chikungunya virus (ChikV) infection is characterized by persistent infection in joints and lymphoid organs. The ChikV Capsid protein plays an important role in regulating virus replication. In this study, we hypothesized that capsid protein
Vu Nghia +6 more
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IEEE Access, 2023 Capsid protein is a pathogenic protein that needs to be examined because it helps in the virus’s proliferation and mutation. Due to this protein, the virus can replicate and reproduce itself.
Anees Ur Rahman Khattak +6 more
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A Unique Role of the Human Cytomegalovirus Small Capsid Protein in Capsid Assembly
mBio, 2022 Morphogenesis of herpesvirus particles is highly conserved; however, the capsid assembly and genome packaging of human cytomegalovirus (HCMV) exhibit unique features.
Eva Maria Borst +8 more
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Large-scale functional purification of recombinant HIV-1 capsid. [PDF]
PLoS ONE, 2013 During human immunodeficiency virus type-1 (HIV-1) virion maturation, capsid proteins undergo a major rearrangement to form a conical core that protects the viral nucleoprotein complexes.
Magdeleine Hung +7 more
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Vaccines, 2021 Porcine circovirus Type 2 (PCV2) is a primary etiological pathogen of post-weaning multi-systemic wasting syndrome (PMWS). The capsid protein of PCV2 is the crucial immunogenic protein which can induce antibody generation and immune responses.
Qingping Luo +6 more
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Assembly of bacteriophage P2 capsids from capsid protein fused to internal scaffolding protein [PDF]
Virus Genes, 2010 Most tailed bacteriophages with double-stranded DNA genomes code for a scaffolding protein, which is required for capsid assembly, but is removed during capsid maturation and DNA packaging. The gpO scaffolding protein of bacteriophage P2 also doubles as a maturation protease, while the scaffolding activity is confined to a 90 residue C-terminal ...
Jenny R, Chang +2 more
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