Results 11 to 20 of about 227,059 (331)

High repetitive arginine in the anterior of PCV3 capsid protein is a severe obstacle for its expression in E. coli

open access: yesAMB Express, 2020
Porcine circovirus type 3 (PCV3) is a novel circovirus identified in sows with PDNS-like clinical signs and reproductive failure. The capsid protein (CAP) of PCV3 is expected to be an effective vaccine candidate.
Bing Yan Liu   +5 more
doaj   +1 more source

The Monoclonal Antibody Recognized the Open Reading Frame Protein in Porcine Circovirus Type 2-Infected Peripheral Blood Mononuclear Cells

open access: yesViruses, 2020
The purpose of this study in the context of the open reading frame 3 (ORF3) protein of porcine circovirus type 2 (PCV2) was especially its location and its relation to the capsid protein and the apoptosis protein in PCV2-infected porcine peripheral blood
Ling-Chu Hung
doaj   +1 more source

Identification of Interactions between Sindbis Virus Capsid Protein and Cytoplasmic vRNA as Novel Virulence Determinants. [PDF]

open access: yesPLoS Pathogens, 2017
Alphaviruses are arthropod-borne viruses that represent a significant threat to public health at a global level. While the formation of alphaviral nucleocapsid cores, consisting of cargo nucleic acid and the viral capsid protein, is an essential ...
Kevin J Sokoloski   +6 more
doaj   +1 more source

Neck and capsid architecture of the robust Agrobacterium phage Milano

open access: yesCommunications Biology, 2023
Large gaps exist in our understanding of how bacteriophages, the most abundant biological entities on Earth, assemble and function. The structure of the “neck” region, where the DNA-filled capsid is connected to the host-recognizing tail remains poorly ...
Ravi R. Sonani   +9 more
doaj   +1 more source

Proton-Linked Dimerization of a Retroviral Capsid Protein Initiates Capsid Assembly [PDF]

open access: yesStructure, 2009
In mature retroviral particles, the capsid protein (CA) forms a shell encasing the viral replication complex. Human immunodeficiency virus (HIV) CA dimerizes in solution, through its C-terminal domain (CTD), and this interaction is important for capsid assembly.
Bailey, Graham   +3 more
openaire   +3 more sources

Mutation of a Conserved Nuclear Export Sequence in Chikungunya Virus Capsid Protein Disrupts Host Cell Nuclear Import

open access: yesViruses, 2017
Transmitted by mosquitoes; chikungunya virus (CHIKV) is responsible for frequent outbreaks of arthritic disease in humans. CHIKV is an arthritogenic alphavirus of the Togaviridae family.
Susan C. Jacobs   +4 more
doaj   +1 more source

Cryo-EM structure in situ reveals a molecular switch that safeguards virus against genome loss

open access: yeseLife, 2020
The portal protein is a key component of many double-stranded DNA viruses, governing capsid assembly and genome packaging. Twelve subunits of the portal protein define a tunnel, through which DNA is translocated into the capsid.
Oliver W Bayfield   +2 more
doaj   +1 more source

Packaging signals in single-stranded RNA viruses: nature’s alternative to a purely electrostatic assembly mechanism [PDF]

open access: yes, 2013
The formation of a protective protein container is an essential step in the life-cycle of most viruses. In the case of single-stranded (ss)RNA viruses, this step occurs in parallel with genome packaging in a co-assembly process.
Bakker, S.E.   +10 more
core   +2 more sources

Diagnostic Potential of Parechovirus Capsid Proteins [PDF]

open access: yesJournal of Clinical Microbiology, 2003
ABSTRACT To study humoral and cellular immunity against human parechovirus type 1 (HPEV1), the viral capsid proteins VP0, VP1, and VP3 were expressed and purified as glutathione S -transferase (GST)-tagged recombinant proteins. The fusion proteins were used to raise antisera in rabbits.
Annu, Alho   +3 more
openaire   +2 more sources

Dengue virus capsid protein usurps lipid droplets for viral particle formation. [PDF]

open access: yesPLoS Pathogens, 2009
Dengue virus is responsible for the highest rates of disease and mortality among the members of the Flavivirus genus. Dengue epidemics are still occurring around the world, indicating an urgent need of prophylactic vaccines and antivirals.
Marcelo M Samsa   +7 more
doaj   +1 more source

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