Results 21 to 30 of about 227,059 (331)
Frontiers in Microbiology, 2022 In the past decade, dengue virus infection is one of the most prevalent and rapidly spreading arthropod-borne diseases worldwide with about 400 million infections every year.
Yaoxing Wu +7 more
doaj +1 more source
Rotavirus Capsid Protein VP5* Permeabilizes Membranes [PDF]
Journal of Virology, 1999 ABSTRACT Proteolytic cleavage of the VP4 outer capsid spike protein into VP8* and VP5* proteins is required for rotavirus infectivity and for rotavirus-induced membrane permeability. In this study we addressed the function of the VP5* cleavage fragment in permeabilizing membranes.
E, Denisova +6 more
openaire +2 more sources
FEZ1 Is Recruited to a Conserved Cofactor Site on Capsid to Promote HIV-1 Trafficking
Cell Reports, 2019 Summary: HIV-1 uses the microtubule network to traffic the viral capsid core toward the nucleus. Viral nuclear trafficking and infectivity require the kinesin-1 adaptor protein FEZ1. Here, we demonstrate that FEZ1 directly interacts with the HIV-1 capsid
Pei-Tzu Huang +6 more
doaj +1 more source
Iodination of Poliovirus Capsid Proteins
Journal of General Virology, 1977 Summary Iodination of the surface of poliovirus and its artificial empty capsid demonstrated predominant labelling of polypeptide VP 1 on the intact particle and an increased labelling of polypeptide VP 2 on the artificial empty capsid.
T W, Beneke +3 more
openaire +2 more sources
Cluster J Mycobacteriophages: Intron Splicing in Capsid and Tail Genes [PDF]
, 2013 Bacteriophages isolated on Mycobacterium smegmatis mc2155 represent many distinct genomes sharing little or no DNA sequence similarity. The genomes are architecturally mosaic and are replete with genes of unknown function.
Best, AA +17 more
core +4 more sources
The Astrovirus Capsid: A Review
Viruses, 2017 Astroviruses are enterically transmitted viruses that cause infections in mammalian and avian species. Astroviruses are nonenveloped, icosahedral viruses comprised of a capsid protein shell and a positive-sense, single-stranded RNA genome.
Carlos F. Arias, Rebecca M. DuBois
doaj +1 more source
In situ structures of the genome and genome-delivery apparatus in a single-stranded RNA virus. [PDF]
, 2016 Packaging of the genome into a protein capsid and its subsequent delivery into a host cell are two fundamental processes in the life cycle of a virus. Unlike double-stranded DNA viruses, which pump their genome into a preformed capsid, single-stranded ...
Dai, Xinghong +6 more
core +1 more source
Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy
Hepatology, EarlyView., 2022 Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann +25 more
wiley +1 more source
Bionanomaterials from plant viruses [PDF]
, 2015 Plant virus capsids have emerged as useful biotemplates for material synthesis. All plant virus capsids are assembled with high-precision, three-dimensional structures providing nanoscale architectures that are highly monodisperse, can be produced in ...
Aljabali, Alaa A. A., Evans, David
core +2 more sources
Multifaceted Capsid Proteins: Multiple Interactions Suggest Multiple Roles for Pepino mosaic virus Capsid Protein [PDF]
Molecular Plant-Microbe Interactions®, 2014 Pepino mosaic virus (PepMV) (family Alphaflexiviridae, genus Potexvirus) is a mechanically transmitted tomato pathogen that, over the last decade, has evolved from emerging to endemic worldwide. Here, two heat-shock cognate (Hsc70) isoforms were identified as part of the coat protein (CP)/Hsc70 complex in vivo, following full-length PepMV and CP ...
Matthaios M. Mathioudakis +4 more
openaire +3 more sources