Results 21 to 30 of about 27,038 (216)

Effect of Captopril on Brain Oxidative Damage in Pentylenetetrazole-Induced Seizures in Mice [PDF]

open access: yesPharmaceutical Sciences, 2019
Background: Frequent seizure is followed by overproduction of free radicals and brain oxidative stress. Renin angiotensin system (RAS) has some effects on central nervous system.
Fereshteh Asgharzadeh   +6 more
doaj   +1 more source

Comparative pharmacodynamics of intranasal and enteral administration of captopril for uncomplicated hypertensive crises

open access: yesAktualʹnì Pitannâ Farmacevtičnoï ì Medičnoï Nauki ta Praktiki, 2021
Uncomplicated hypertensive crises without acute or progressive damage to the target organs pose a potential threat to the patient’s life and require rapid reduction of arterial pressure within hours or days in an outpatient setting. The existing protocol
I. L. Kechyn   +2 more
doaj   +1 more source

Participation of kinins in the inhibitory action of captopril on acute hypertension induced by L-NAME in anesthetized rats

open access: yesBrazilian Journal of Medical and Biological Research, 1997
The aim of the present study was to investigate the role of bradykinin in the inhibitory action of captopril in hypertension induced by L-NAME in anesthetized rats.
R. Soares de Moura, M. Cardoso
doaj   +1 more source

Promising results of captopril in improving knee arthrofibrosis and cartilage status: an animal model study

open access: yesJournal of Experimental Orthopaedics, 2022
Purpose Several cytokines and growth factors start and progress the destruction process of joint hyaline cartilage and fibrosis formation. Captopril is classified as an Angiotensin‐converting enzyme inhibitor in which several studies revealed that ...
Seyed Ali Hashemi   +4 more
doaj   +1 more source

The in‐hospital administration of sacubitril/valsartan in acute myocardial infarction: A meta‐analysis

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 998-1012, April 2025.
In patients with Acute Myocardial Infarction related heart failure, the in‐hospital administration of ARNIs was associated with a reduced risk of MACEs and re‐hospitalizations for heart failure, as well as cardiac remodeling, compared to standard therapy.
Gianluca Di Pietro   +15 more
wiley   +1 more source

Sustained Release of Captopril Tablet with Floating System Using a Cross-Linked Matrix of Alginate

open access: yesKartika: Jurnal Ilmiah Farmasi, 2019
Captopril has a short biological half-life 2-3 hours and has been used for long-term treatment of hypertension. The properties of captopril such as absorbed well in the stomach, freely water-soluble, instability in intestinal environment, and ...
Dhadhang Wahyu Kurniawan   +2 more
doaj   +1 more source

Cardiac remodelling in the era of the recommended four pillars heart failure medical therapy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1029-1044, April 2025.
Abstract Cardiac remodelling is a key determinant of worse cardiovascular outcome in patients with heart failure (HF) and reduced ejection fraction (HFrEF). It affects both the left ventricle (LV) structure and function as well as the left atrium (LA) and the right ventricle (RV).
Giada Colombo   +7 more
wiley   +1 more source

Determinação de captopril por HPLC acoplado a espectômetro de massa: aplicação em estudo de bioequivalência - doi: 10.5020/18061230.2012.p13

open access: yesRevista Brasileira em Promoção da Saúde, 2012
Objetivo: Avaliar a bioequivalência de três diferentes formulações de captopril 25mg (Capoten® como formulação de referência e Captopril produzido pela FURP e Farmanguinhos como formulações testes) em 24 voluntários saudáveis de ambos os sexos.
Aline Kércia Alves Soares   +4 more
doaj   +1 more source

Harnessing Free Radical Scavenging Potential of Caffeic Acid as a Nutraceutical—A Review

open access: yesFood Safety and Health, EarlyView.
Caffeic acid has emerged as a promising bioactive molecule with multiple pharmacological properties, including antioxidant, antimicrobial, anti‐inflammatory, organ protective properties and metal‐chelating ability. This review emphasizes the dietary sources, structural characteristic, molecular mechanism underlying health promoting effects of caffeic ...
Pavitra Behra   +2 more
wiley   +1 more source

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

open access: yesiMetaMed, EarlyView.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu   +6 more
wiley   +1 more source

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