Results 1 to 10 of about 4,213,151 (329)
Conventional CARs versus modular CARs [PDF]
Abstract The clinical application of immune effector cells genetically modified to express chimeric antigen receptors (CARs) has shown impressive results including complete remissions of certain malignant hematological diseases. However, their application can also cause severe side effects such as cytokine release syndrome (CRS) or tumor ...
Feldmann, A. +5 more
openaire +2 more sources
CD28z CARs and Armored CARs [PDF]
CD19-targeted chimeric antigen receptor (CAR) T cells are currently being tested in the clinic with very promising outcomes. However, limitations to CAR T cell therapy exist. These include lack of efficacy against some tumors, specific targeting of tumor cells without affecting normal tissue and retaining activity within the suppressive tumor ...
Hollie J, Pegram +2 more
openaire +2 more sources
Este artículo presenta el diseño y desarrollo de una arquitectura electrónica bioinspirada en el sistema motor humano para sistemas de asistencia a la locomoción, como es en el caso de exoesqueletos de asistencia o de rehabilitación.
Gabriel Delgado-Oleas +4 more
doaj +1 more source
Kinetic theory of quantum transport at the nanoscale [PDF]
We present a quantum-kinetic scheme for the calculation of non-equilibrium transport properties in nanoscale systems. The approach is based on a Liouville-master equation for a reduced density operator and represents a generalization of the well-known ...
Car, Roberto, Gebauer, Ralph
core +1 more source
Robot Transparency and Anthropomorphic Attribute Effects on Human–Robot Interactions
Anthropomorphic robots need to maintain effective and emotive communication with humans as automotive agents to establish and maintain effective human–robot performances and positive human experiences. Previous research has shown that the characteristics
Jianmin Wang +6 more
doaj +1 more source
Child abuse, child protection and disabled children : a review of recent research [PDF]
This paper reports the results of a scoping study which reviewed research about child abuse, child protection and disabled children published in academic journals between 1996 - 2009. The review was conducted using a five stage method for scoping studies.
Agnew +42 more
core +1 more source
CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy
AbstractAdoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. However, CAR immunotherapy in solid tumors lags significantly behind.
Kevin Pan +5 more
openaire +3 more sources
Introduction: The discovery of vitamin D muscle receptors in the last few years suggested a significant role in muscle tissue, pointing out athletes as a special group. Specific data are scarce.
Jara Valtueña +4 more
doaj +1 more source
Investigations of the frequency of bending vibrations of the car bodies of 61-4440 model range, which includes compartment cars, staff cars, non-compartment cars, coach cars, restaurant cars and others, are described. The bodies of all cars of this model
A. N. Skachkov +4 more
doaj +1 more source
ANALYSIS OF ENERGY SAVING AND ENERGY EFFICIENCY ISSUES DURING OPERATION OF THE METRO ROLLING STOCK
Purpose.Nowadays a problem of significant power consumption of the rolling stock during its operation is a current issue. In connection with staged electricity rates increase further development of the rail electric transport, including metro rolling ...
A. V. Donchenko +4 more
doaj +1 more source

