Results 1 to 10 of about 4,213,151 (329)

Conventional CARs versus modular CARs [PDF]

open access: yesCancer Immunology, Immunotherapy, 2019
Abstract The clinical application of immune effector cells genetically modified to express chimeric antigen receptors (CARs) has shown impressive results including complete remissions of certain malignant hematological diseases. However, their application can also cause severe side effects such as cytokine release syndrome (CRS) or tumor ...
Feldmann, A.   +5 more
openaire   +2 more sources

CD28z CARs and Armored CARs [PDF]

open access: yesThe Cancer Journal, 2014
CD19-targeted chimeric antigen receptor (CAR) T cells are currently being tested in the clinic with very promising outcomes. However, limitations to CAR T cell therapy exist. These include lack of efficacy against some tumors, specific targeting of tumor cells without affecting normal tissue and retaining activity within the suppressive tumor ...
Hollie J, Pegram   +2 more
openaire   +2 more sources

Diseño y desarrollo de una arquitectura electrónica bioinspirada para el control de sistemas de asistencia a la locomoción

open access: yesRevista Iberoamericana de Automática e Informática Industrial RIAI, 2023
Este artículo presenta el diseño y desarrollo de una arquitectura electrónica bioinspirada en el sistema motor humano para sistemas de asistencia a la locomoción, como es en el caso de exoesqueletos de asistencia o de rehabilitación.
Gabriel Delgado-Oleas   +4 more
doaj   +1 more source

Kinetic theory of quantum transport at the nanoscale [PDF]

open access: yes, 2004
We present a quantum-kinetic scheme for the calculation of non-equilibrium transport properties in nanoscale systems. The approach is based on a Liouville-master equation for a reduced density operator and represents a generalization of the well-known ...
Car, Roberto, Gebauer, Ralph
core   +1 more source

Robot Transparency and Anthropomorphic Attribute Effects on Human–Robot Interactions

open access: yesSensors, 2021
Anthropomorphic robots need to maintain effective and emotive communication with humans as automotive agents to establish and maintain effective human–robot performances and positive human experiences. Previous research has shown that the characteristics
Jianmin Wang   +6 more
doaj   +1 more source

Child abuse, child protection and disabled children : a review of recent research [PDF]

open access: yes, 2012
This paper reports the results of a scoping study which reviewed research about child abuse, child protection and disabled children published in academic journals between 1996 - 2009. The review was conducted using a five stage method for scoping studies.
Agnew   +42 more
core   +1 more source

CAR race to cancer immunotherapy: from CAR T, CAR NK to CAR macrophage therapy

open access: yesJournal of Experimental & Clinical Cancer Research, 2022
AbstractAdoptive cell therapy with chimeric antigen receptor (CAR) immunotherapy has made tremendous progress with five CAR T therapies approved by the US Food and Drug Administration for hematological malignancies. However, CAR immunotherapy in solid tumors lags significantly behind.
Kevin Pan   +5 more
openaire   +3 more sources

High prevalence of vitamin D insufficiency among elite Spanish athletes: the importance of outdoor training adaptation

open access: yesNutrición Hospitalaria, 2014
Introduction: The discovery of vitamin D muscle receptors in the last few years suggested a significant role in muscle tissue, pointing out athletes as a special group. Specific data are scarce.
Jara Valtueña   +4 more
doaj   +1 more source

Development and evaluation of a complex of studies to increase the frequency of bending vibrations of modern passenger car bodies

open access: yesВестник Научно-исследовательского института железнодорожного транспорта, 2021
Investigations of the frequency of bending vibrations of the car bodies of 61-4440 model range, which includes compartment cars, staff cars, non-compartment cars, coach cars, restaurant cars and others, are described. The bodies of all cars of this model
A. N. Skachkov   +4 more
doaj   +1 more source

ANALYSIS OF ENERGY SAVING AND ENERGY EFFICIENCY ISSUES DURING OPERATION OF THE METRO ROLLING STOCK

open access: yesNauka ta progres transportu, 2016
Purpose.Nowadays a problem of significant power consumption of the rolling stock during its operation is a current issue. In connection with staged electricity rates increase further development of the rail electric transport, including metro rolling ...
A. V. Donchenko   +4 more
doaj   +1 more source

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