Results 251 to 260 of about 4,154,700 (310)

Enforced BATF expression via clinically approved LNPs enhances adoptive T-cell therapies. [PDF]

Blood Sci
Ge H, Wang K, Chen L, Yin T, Zhang F, Li H, Wei J, Ding D, Zheng W.   +8 more
europepmc   +1 more source

An On‐Demand Neuromorphic Vision System Enabled by a Multi‐Paradigm Neuromorphic Device and Hierarchical Reconfigurability Designed from Device to System Level

Advanced Science, EarlyView.
An on‐demand ultra‐reconfigurable intelligent vision system with hierarchical reconfigurability from device to system levels is demonstrated. Through co‐design of a multi‐paradigm device, reconfigurable circuits, and adaptive system architecture/algorithms, the system enables seamless switching among spiking, non‐spiking, neuromorphic imaging (NI), and
Biyi Jiang, Jiayi Xu, Liang Ran, Xinhe Feng, Khalil Harrabi, Yida Li, Longyang Lin, Feichi Zhou   +7 more
wiley   +1 more source

Endogenous CD28 Drives the Persistent Activity of CAR T Cells in Myeloma and Lymphoma Models. [PDF]

Blood Cancer Discov
Lieberman MM, Tong JH, Odukwe NU, Chavel CA, Bishara GG, Crasti KM, Herr MM, Goala P, Purdon TJ, Burchett R, Gillard BM, Brackett CM, Tario JD, Rosario SR, McGray AJR, Bramson JL, Davila ML, Brentjens RJ, Malek E, Lee KP, Olejniczak SH.   +20 more
europepmc   +1 more source

Ecological Adaptation Mechanisms Underlying Successful Plant Reproduction

Advanced Science, EarlyView.
During floral induction, various environmental and endogenous signals converge to regulate the florigen protein, which is transported from leaves to the SAM to initiate flowering. Within the SAM, a complex network of receptor kinases and small peptides orchestrates floral development with high spatiotemporal precision.
Hang Zhao, Shenghui Huo, Yue Xing, Shuxin Zhang, Guilin Li, Yihui Liu, Chongyang Jin, Fuguang Li, Xiaoyang Ge   +8 more
wiley   +1 more source

Preventing trogocytosis by cathepsin B inhibition augments CAR T-cell function. [PDF]

Signal Transduct Target Ther
Dietze KA, Nguyen K, Pathni A, Fazekas F, Sun W, Rosati E, Baker JM, Galeana Figueroa M, Gebru E, Yamoah D, Mulatu R, Wang A, Rapoport AP, Lum DH, Fan X, Radhakrishnan SV, Atanackovic D, Upadhyaya A, Luetkens T.   +18 more
europepmc   +1 more source

Longitudinal real-world surveillance of infection outcomes in CAR-T and bispecific therapy recipients: the CLARITY study protocol. [PDF]

BMJ Open
Reynolds GK, Anderson MA, Thursky K, Teh BW, Slavin MA.   +4 more
europepmc   +1 more source

Heparanase-Loaded CAR T Extracellular Vesicles Remodel the Colorectal Tumour Microenvironment and Boost T Cell Antitumor Immunity. [PDF]

J Extracell Vesicles
Zhu S, Yin J, Yang W, Fu X, Zeng Y, Huang N, Zhang L, Yu C, Ouyang P, Huang K, Chen R, Zhao X, Jiang D, Xu G.   +13 more
europepmc   +1 more source

Immunotherapy of diffuse large B-cell lymphoma: from monoclonal antibodies to cellular therapies. A narrative review. [PDF]

Front Immunol
Aureli A, Lanzilli G, Boccadamo Pompili SV, Spagnoli GC, Sconocchia G, Caratelli S.   +5 more
europepmc   +1 more source

Lipid nanoparticle mRNA delivery preserves CAR T cell cytotoxicity and limits exhaustion compared to electroporation. [PDF]

Mol Ther Nucleic Acids
Picht S, Farrera-Sal M, Hiller AL, Brumhard S, Klaas AM, Schulenberg S, Friedrich R, Scholz C, Hemmerling L, Simon DN, Krönke G, Pichon C, Sander LE, Volk HD, Gossen M, Schmueck-Henneresse M, Drzeniek NM.   +16 more
europepmc   +1 more source

Targeting CD74 may mitigate immune-escape features and enhance BCMA CAR-T activity in preclinical models of relapsed/refractory multiple myeloma. [PDF]

J Immunother Cancer
Chen X, Zhang J, Chen H, Huang R, Zhou X, Wang H, Xiao H, Peng Q, Wu F, Zhai Z, Wang Z.   +10 more
europepmc   +1 more source