Results 51 to 60 of about 157,141 (260)

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta, Jeremy D. Rubinstein, Christopher E. Dandoy, Ruby Khoury, Angela Faulhaber, Christine L. Phillips, Christa Krupski   +6 more
wiley   +1 more source

Calibrating Car-Following Model Considering Measurement Errors

Advances in Mechanical Engineering, 2013
Car-following model has important applications in traffic and safety engineering. To enhance the accuracy of model in predicting behavior of individual driver, considerable studies strive to improve the model calibration technologies.
Chang-qiao Shao, Xiao-ming Liu, Zhi-yong Zhang   +2 more
doaj   +1 more source

Modeling for Micro Traffic Flow with the Consideration of Lateral Vehicle’s Influence

Journal of Advanced Transportation, 2020
In order to make the car-following model describe the driving behavior of vehicle on urban road more accurately, existing car-following models are simulated using measured traffic data. According to the analysis of the simulation result, two new improved
Da-wei Liu, Zhong-ke Shi, Wen-Huan Ai
doaj   +1 more source

Instabilities in car following and multi-anticipative car following models

Nonlinear Dynamics
Abstract Microscopic models of traffic depend on how the dynamics of one vehicle following another is considered. Such models play a key role in design, optimisation, performance and control of transportation networks. Based on how these models are constructed, instabilities in traffic are observed, which may be observed in real life ...
Ranganatha Belagumba Ramachandra, Bidisha Ghosh, Vikram Pakrashi   +2 more
openaire   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Virtual Vehicle Simulation Method Based on Car-following Model [PDF]

Jisuanji gongcheng, 2016
In the urban traffic simulation,vehicles start slowly with the existing Intelligent-driver Model(IDM).To solve this problem,this paper proposes an improved IDM,which considers how vehicle distance affects vehicle velocitiy,uses acceleration term based on
LU Tao,LIU Zhen,LIU Tingting,LIU Cuijuan,CHAI Yanjie,FANG Hao
doaj   +1 more source

Solitons and kinks in a general car-following model [PDF]

Physical Review E, 2013
We study a car-following model of traffic flow which assumes only that a car's acceleration depends on its own speed, the headway ahead of it, and the rate of change of headway, with only minimal assumptions about the functional form of that dependence.
openaire   +3 more sources

PARK(ing) time–How park deficiency affects the biological clock in a Drosophila model of Parkinson's disease

FEBS Letters, EarlyView.
Drosophila park mutants serve as a model for Parkinson's disease. We used this strain to investigate the connection between oxidative stress and the circadian clock mechanism. We showed that increased oxidative stress affects the physiology of pacemaker cells, disrupting their daily structural plasticity. Lack of rhythmic signaling from pacemaker cells
Kamila Zientara, Kinga Skoczek, Elzbieta Pyza, Milena Damulewicz   +3 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Modeling and Simulating Urban Traffic Flow Mixed With Regular and Connected Vehicles

IEEE Access, 2021
In the upcoming decades, connected vehicles will join regular vehicles on the road, and the characteristics of traffic flows will change accordingly. To better understand mixed traffic flow (regular vehicles and connected vehicles) characteristics, a ...
Zuping Cao, Lili Lu, Chen Chen, Xu Chen
doaj   +1 more source