Results 61 to 70 of about 18,788,717 (252)
Journal of Sensor and Actuator Networks, 2020 One of the current topics of interest in transportation science is the use of intelligent computation and IoT (Internet of Things) technologies. Researchers have proposed many approaches using these concepts, but the most widely used concept in road ...
Mădălin-Dorin Pop +2 more
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Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
, 1983 Le ha correspondido, a la corporación CAR, durante este tiempo una etapa particularmente dinámica e interesante. La Corporación había venido consolidándose como entidad líder en la región y modelo de entidades similares.
Corporación Autónoma Regional de Cundinamarca – CAR
core
Stochastic parameter-optimized car-following model considering heterogeneous traffic flow
Shenzhen Daxue xuebao. Ligong banIn order to examine the impact of traffic flow heterogeneity on vehicle following behavior, we propose an improved optimized speed function based on the stochastic parametric linear regression method.
PAN Yiyong, QUAN Yongjun, GUAN Xingyu
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Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
Molecular Oncology, EarlyView.We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
The development of a naturalistic car following model for assessing managed motorway systems' safety effects [PDF]
, 2013 This thesis highlights the limitations of the existing car following models to emulate driver behaviour for safety study purposes. It also compares the capabilities of the mainstream car following models emulating driver behaviour precise parameters such
Bevrani, Kaveh
core
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
FEBS Open Bio, EarlyView.Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
A Safety Control Method of Car-Following Trajectory Planning Based on LSTM
Promet (Zagreb), 2023 This paper focuses on the potential safety hazards of collision in car-following behaviour generated by deep learning models. Based on an intelligent LSTM model, combined with a Gipps model of safe collision avoidance, a new, Gipps-LSTM model is ...
Xingyu Chen +4 more
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