Results 81 to 90 of about 11,974,013 (294)

Effects of IGFBP4 deficiency on human preadipocyte proliferation and differentiation through the IGF1R/AKT pathway

open access: yesFEBS Open Bio, EarlyView.
IGFBP4 knockdown (KD) impairs preadipocyte proliferation and is associated with IGF1R protein downregulation and attenuated AKT phosphorylation. The mechanisms by which IGFBP4 KD influences the IGF1R/AKT signaling pathway involve newly synthesized proteins and lysosomal degradation pathways. Created in BioRender.
Yujia Guo   +6 more
wiley   +1 more source

Human-Inspired Learning for Car Following Models

open access: yesIFAC-PapersOnLine
In this paper, we propose a human-inspired learning mechanism in the context of car following models. We use a memory structure to gather information from other drivers and make inferences about their driving styles. Then, this information is used to determine the ideal driving strategy.
Al Habboush, Seymanur   +2 more
openaire   +2 more sources

Yeast Gcn2 retains activity following humanization of its auto‐phosphorylation region

open access: yesFEBS Open Bio, EarlyView.
Using Saccharomyces cerevisiae as a model to study Gcn2 activation and regulation is limited by the lack of antibodies detecting phosphorylated Gcn2. To overcome this, we engineered Gcn2‐HsC, a yeast Gcn2 variant recognizable by commercial anti‐human phospho‐GCN2 antibodies.
Reuben A. Anderson   +2 more
wiley   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

open access: yesFEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss   +7 more
wiley   +1 more source

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

open access: yesFEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph   +7 more
wiley   +1 more source

A knowledge-informed deep learning paradigm for generaliz-able and stability-optimized car-following models

open access: yesCommunications in Transportation Research
Car-following models (CFMs) are fundamental to traffic flow analysis and autonomous driving. Although calibrated physics-based and trained data-driven CFMs can replicate human driving behavior, their reliance on specific datasets limits generalization ...
Chengming Wang   +5 more
doaj   +1 more source

Acuerdo No. 40 del 18 de diciembre de 2018

open access: yes, 2018
Por medio del cual se establece la meta global de carga contaminante de DBO5 y SST para la cuenca del río Seco y otros afluentes al Magdalena, para el periodo comprendido entre el 1 de enero de 2018 y el 31 de diciembre de ...
Corporación Autónoma Regional de Cundinamarca – CAR
core  

Neurovascular Contacts in the Pathophysiology of Neuralgic Amyotrophy: An Observational Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neuralgic amyotrophy (NA) is a prevalent, monophasic, multifocal immune‐mediated neuropathy. A distinctive characteristic of the disease is the occurrence of nerve or fascicle constrictions and torsions (NA‐associated focal nerve lesions, NAFL). The pathophysiology underlying this phenomenon remains to be fully elucidated.
Johannes Fabian Holle   +4 more
wiley   +1 more source

Home - About - Disclaimer - Privacy