Results 211 to 220 of about 832,259 (254)

The microbiome and brain metastasis in non‐small cell lung cancer: A graded appraisal and a framework for prevention‐oriented research

Clinical and Translational Medicine, Volume 16, Issue 11, November 2026.
This Review proposes a microbiome–premetastatic brain niche axis connecting gut, lung, and intratumoral microbes with metabolites, blood–brain barrier remodeling, neuroimmune priming, and brain metastasis in NSCLC. It integrates current evidence while distinguishing established mechanisms from associations and hypotheses requiring prospective and ...
Long Liang, Fangjuan Hu, Xiaofeng Wang, Chunhan Tang, Chun Wang, Gefei Jiang, Chungang Zhao, Yin Zhang, Churong Li   +8 more
wiley   +1 more source

Immune Regulation by Regnase‐1 and Related Endoribonucleases

European Journal of Immunology, Volume 56, Issue 11, November 2026.
Regnase‐1 couples immune signaling to stem‐loop‐mediated mRNA decay. Its biological output depends on cellular and tissue context, determining whether it restrains inflammation, maintains tissue homeostasis, or suppresses inflammation‐associated tumorigenesis.
Takuya Uehata, Osamu Takeuchi
wiley   +1 more source

Engineering immunity with CAR-NK cells: advancing the frontiers of cancer immunotherapy. [PDF]

Front Pharmacol
Cianga VA, Antohe I, Minciună C, Dăscălescu A.   +3 more
europepmc   +1 more source

Glial Dysfunction and Memory Impairments in a Model of Pediatric Obstructive Sleep Apnea

Glia, Volume 74, Issue 11, November 2026.
Generation and analysis of an snRNA‐seq atlas of the hippocampus in POSA. Validation of reduced protein expression of six genes across four cell types. Cellular‐level investigation of aberrant glial function in POSA using transgenic reporter mice. ABSTRACT Pediatric obstructive sleep apnea (POSA) is a common childhood disease that often causes aberrant
Michael R. Williamson, Jorge Botas, Mahyar J. Hedayatpour, Thea Zlatkov, Akdes Serin Harmanci, Christopher J. Yates, Kenneth Nobleza, Roshan Ailani, Adam C. Adler, Farrah Kheradmand, Hyun Kyoung Lee, Benjamin Deneen, Hyun‐Hwan Jeong, Arvind Chandrakantan   +13 more
wiley   +1 more source

Proof-of-Concept Evaluation of Primary Human FAP-CAR-NK Cells Targeting Activated Fibroblasts in Pulmonary Fibrosis. [PDF]

Int J Mol Sci
Wu G, Ling Z, Lin W, Wang Y, Liu X, Wang J.   +5 more
europepmc   +1 more source

Lineage switch in childhood leukemia

HemaSphere, Volume 10, Issue 11, November 2026.
Abstract Lineage switch (LS) is a rare but aggressive immunophenotypic transformation of acute leukemia associated with limited therapeutic options and poor clinical outcome. Although LS has been increasingly recognized in the era of CD19‐directed immunotherapies, its biological basis remains incompletely understood.
Katharina Daugs, Anna Prazmo, Anindita Roy, Arndt Borkhardt   +3 more
wiley   +1 more source

Synergistic immunotherapeutic effects of irreversible electroporation and CAR-NK cell therapy against hepatocellular carcinoma. [PDF]

Signal Transduct Target Ther
Park JD, Shin HE, Jang HJ, Ko S, An YS, Lee JS, Moon S, Seo H, Kim Y, Kim Y, Han JH, Park CG, Kim DH, Park W.   +13 more
europepmc   +1 more source

Tunable CAR-NK-92 activity in the tumor microenvironment via a dual ATF4-responsive circuit. [PDF]

Front Immunol
Manchon E, Hirt N, Soundiramourty A, Versier B, Christen Y, Charron D, Mallet J, Jabrane-Ferrat N, Serguera C, Al-Daccak R.   +9 more
europepmc   +1 more source

Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors. [PDF]

Cell Rep Med
Zhang H, Li S, Liu C, Gongye X, Li H, Ji Y, Ju CW, Jia W, Niu X, Guan Y, Zhai X, Jin B, Xia P.   +12 more
europepmc   +1 more source

Comprehensive Immune Repertoires of T Cell Receptor and B Cell Receptor Identify Key Immune Features Associated With Disease Activity of Systemic Lupus Erythematosus

MedComm, Volume 7, Issue 11, November 2026.
To characterize systemic immune features associated with disease activity, peripheral blood was collected from 32 active SLE patients, 30 stable SLE patients, and 35 healthy donors. Comprehensive immune profiling was performed using flow cytometry, immune repertoire sequencing, and bulk RNA sequencing.
Jingyi Wu, Zhuochao Zhou, Anrui Yu, Xia Lin, Yuyang Ren, Jialin Teng, Dehao Zhu, Fan Wang, Yijun You, Xiangjun Ji, Puyu Wang, Hongpu Li, Chengde Yang, Wenbo Wang, Yawei Du, Junna Ye   +15 more
wiley   +1 more source