Results 271 to 280 of about 812,191 (301)
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Best Practice & Research Clinical Haematology, 2018
The clinical success achieved using CD19-directed CAR-T cells has stimulated many academic institutions to explore the feasibility of manufacturing these, and other CAR-T cells, in-house. This article reviews the issues that must be addressed in order to achieve this goal.
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The clinical success achieved using CD19-directed CAR-T cells has stimulated many academic institutions to explore the feasibility of manufacturing these, and other CAR-T cells, in-house. This article reviews the issues that must be addressed in order to achieve this goal.
openaire +2 more sources
Immunophenotypic Analysis of CAR-T Cells
2019CAR-T cell immunotherapy is a promising therapeutic modality for cancer patients. The success of CAR-T cell therapy has been associated with the phenotype, activation and functional profiling of infused CAR-T cells. Therefore, immunophenotypic characterization of CAR-T cells during bioprocess is crucial for cell quality control and ultimately for ...
Júlia Teixeira Cottas, de Azevedo +3 more
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Manufacture of CAR-T cells in the body
Nature Biotechnology, 2017Engineered T cells for cancer therapy are produced in the mouse bloodstream, avoiding the need to harvest T cells and manipulate them ex vivo.
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Hematology/Oncology Clinics of North America, 2023
Caron A. Jacobson, Parth S. Shah
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Caron A. Jacobson, Parth S. Shah
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Critical care management of chimeric antigen receptor T‐cell therapy recipients
Ca-A Cancer Journal for Clinicians, 2022Alexander Shimabukuro-Vornhagen +2 more
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Long-term outcomes following CAR T cell therapy: what we know so far
Nature Reviews Clinical Oncology, 2023James N Kochenderfer
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Enhanced safety and efficacy of protease-regulated CAR-T cell receptors
Cell, 2022Louai Labanieh +2 more
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Side-effect management of chimeric antigen receptor (CAR) T-cell therapy
Annals of Oncology, 2021K Jordan +2 more
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