Results 271 to 280 of about 614,006 (307)

CAR T-cell therapy for gliomas

Current Opinion in Neurology
Purpose of review To review the landscape of chimeric antigen receptor T-cell (CAR T) therapy for gliomas as seen in recently published trials and discuss on-going challenges with new cancer immunotherapy treatments. Recent findings Given how CAR T therapy has revolutionized the ...
Kun-Wei, Song, Brian J, Scott
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CAR-T Cells

MedScien
CAR-T (Chimeric antigen receptor T) cell therapy is an immunotherapy especially effective in treating hematological tumors.
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Tracing the Path of CAR T Cells

Cancer Discovery, 2017
Abstract Adding a radioactive tag to CAR T cells has allowed these engineered cells to be monitored as they home in on brain tumors in patients. The technique could help promote a deeper understanding of why this immunotherapy isn't more broadly effective, and why resistance sometimes develops.
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GMP CAR-T cell production

Best Practice & Research Clinical Haematology, 2018
The clinical success achieved using CD19-directed CAR-T cells has stimulated many academic institutions to explore the feasibility of manufacturing these, and other CAR-T cells, in-house. This article reviews the issues that must be addressed in order to achieve this goal.
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Immunophenotypic Analysis of CAR-T Cells

2019
CAR-T cell immunotherapy is a promising therapeutic modality for cancer patients. The success of CAR-T cell therapy has been associated with the phenotype, activation and functional profiling of infused CAR-T cells. Therefore, immunophenotypic characterization of CAR-T cells during bioprocess is crucial for cell quality control and ultimately for ...
Júlia Teixeira Cottas, de Azevedo, Amanda, Mizukami, Pablo Diego, Moço, Kelen Cristina Ribeiro, Malmegrim   +3 more
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Manufacture of CAR-T cells in the body

Nature Biotechnology, 2017
Engineered T cells for cancer therapy are produced in the mouse bloodstream, avoiding the need to harvest T cells and manipulate them ex vivo.
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CAR-T cell therapy

Medicina Clínica (English Edition), 2021
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CAR T-Cell

Hematology/Oncology Clinics of North America, 2023
Caron A. Jacobson, Parth S. Shah
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Peritransplant CAR-T cells

Blood, 2023
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Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade

Cancer Cell, 2021
Shivani Srivastava, Scott Furlan, Carolina Berger   +2 more
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