Results 41 to 50 of about 382,335 (262)
Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig +7 more
wiley +1 more source
Manufacturing of 3D Printed Soft Grippers: A Review
Soft robotics technology has been rapidly expanding in recent years due to its advantages in flexibility and safety for human operators. Within this trend, soft grippers enable more delicate and adaptable manipulations, minimizing damage to the final ...
Kai Blanco +3 more
doaj +1 more source
Background People diagnosed with neurological pathology may experience gait disorders that affect their quality of life. In recent years, research has been carried out on a variety of exoskeletons in this population.
C. Cumplido-Trasmonte +7 more
doaj +1 more source
Raman‐based label‐free microscopic analysis of the pancreas in living zebrafish larvae
Forward stimulated Raman scattering (F‐SRS) and epi coherent anti‐Stokes Raman scattering (E‐CARS) allow label‐free discrimination of distinct subcellular structures in the pancreas of living zebrafish larvae. Given the straightforward applicability, we anticipate broad implementation of Raman microscopy in other organs and across various biomedical ...
Noura Faraj +3 more
wiley +1 more source
[Objective] The architecture of traditional urban rail transit train control system faces challenges such as complex train network topology and wiring, increased delays in subsystem interactions, and poor coordination in complex control processes.
YANG Weijun +5 more
doaj +1 more source
In the above-named article, the affiliation of the authors should have been "Centre for Automation and Robotics (CAR), Universidad Politécnica de Madrid (UPM), 28006 Madrid, Spain."
Juan Jesus Roldan +4 more
doaj +1 more source
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
BackgroundThe sustainability of aquaculture is increasingly threatened by major challenges such as aquatic pollution, excessive water abstraction, and climate change.
Neeraj Kumar +2 more
doaj +1 more source
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani +6 more
wiley +1 more source

