Results 1 to 10 of about 28,706 (230)
In vitro study of spontaneous motility and cholinergic responses in the human Hirschsprung's disease colon [PDF]
BackgroundThe current standard treatment of Hirschsprung's disease (HD) involves complete resection of the aganglionic intestinal segment with routine rectal irrigation pre- and postoperatively.
Felix Schulze +7 more
doaj +2 more sources
Comparisons of urinary bladder responses to common antimuscarinics reveals unique effects of darifenacin [PDF]
IntroductionAntimuscarinics are the first-line pharmaceutical treatment for overactive bladder (OAB). However, some literature suggests that responses to these antimuscarinics can influence a variety of non-muscarinic receptors.
Vineesha Veer +2 more
doaj +2 more sources
Mechanisms of carbachol oscillations
Netoff Theoden I +2 more
doaj +3 more sources
Water Drinking Behavior Associated with Aversive Arousal in Rats: An Integrative Approach
Cholinergic muscarinic stimulation of vast areas of the limbic brain induced a well-documented polydipsia in laboratory rats. This excessive water-drinking behavior has not received any convincing biological and physiological interpretation for the last ...
Stefan M. Brudzynski
doaj +1 more source
A Cholinergic Synaptically Triggered Event Participates in the Generation of Persistent Activity Necessary for Eye Fixation [PDF]
An exciting topic regarding integrative properties of the nervous system is how transient motor commands or brief sensory stimuli are able to evoke persistent neuronal changes, mainly as a sustained, tonic action potential firing.
Alvarado, Juan Carlos +5 more
core +4 more sources
KV7 Channel Expression and Function Within Rat Mesenteric Endothelial Cells
Background and Purpose: Arterial diameter is dictated by the contractile state of the vascular smooth muscle cells (VSMCs), which is modulated by direct and indirect inputs from endothelial cells (ECs).
Samuel N. Baldwin +4 more
doaj +1 more source
Recent studies have implicated impaired Parvalbumin Fast-Spiking Interneuron (PVIN) function as a precipitating factor underlying abnormalities in network synchrony, oscillatory rhythms, and cognition associated with Alzheimer’s disease (AD).
Connie A. Mackenzie-Gray Scott +9 more
doaj +1 more source
Dysphania ambrosioides (L.) Mosyakin and Clemants is an annual or ephemeral perennial herb used traditionally in the Mediterranean region in folk medicine to treat various illnesses, including those related to the digestive system.
Fahd Kandsi +9 more
doaj +1 more source
Muscarinic Receptors as Targets for Metronomic Therapy in Ovarian Cancer
Aim: In this study, the effects of muscarinic acetylcholine receptor (mAChR) agonist carbachol on the proliferation of cisplatin-resistant (A2780cis) and cisplatin-free (SKOV-3) ovarian cancer cell line were for the first time investigated to further ...
Fatma Söylemez +1 more
doaj +1 more source
Carbachol and Nicotine in Prefrontal Cortex Have Differential Effects on Sleep-Wake States
The role of the brainstem cholinergic system in the regulation of sleep-wake states has been studied extensively but relatively little is known about the role of cholinergic mechanisms in prefrontal cortex in the regulation of sleep-wake states.
Anjum Parkar +11 more
doaj +1 more source

