Results 1 to 10 of about 38,951 (272)
In vitro study of spontaneous motility and cholinergic responses in the human Hirschsprung's disease colon [PDF]
Frontiers in PediatricsBackgroundThe current standard treatment of Hirschsprung's disease (HD) involves complete resection of the aganglionic intestinal segment with routine rectal irrigation pre- and postoperatively.
Felix Schulze +7 more
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Elucidating the Urothelial-Dependent and -Independent Mechanisms Involved in the Mouse Bladder Contractility Alterations by Acute Methylglyoxal Exposure [PDF]
BiomedicinesBackground/Objectives: Methylglyoxal (MGO) and subsequent activation of advanced glycation end products (AGEs)–RAGE receptor signaling has been implicated in the complications of diabetes mellitus (DM), such as bladder dysfunction. Chronic treatment with
Akila Lara Oliveira +7 more
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Mechanisms of carbachol oscillations
BMC Neuroscience, 2007 Netoff Theoden I +2 more
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Water Drinking Behavior Associated with Aversive Arousal in Rats: An Integrative Approach
Brain Sciences, 2022 Cholinergic muscarinic stimulation of vast areas of the limbic brain induced a well-documented polydipsia in laboratory rats. This excessive water-drinking behavior has not received any convincing biological and physiological interpretation for the last ...
Stefan M. Brudzynski
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KV7 Channel Expression and Function Within Rat Mesenteric Endothelial Cells
Frontiers in Physiology, 2020 Background and Purpose: Arterial diameter is dictated by the contractile state of the vascular smooth muscle cells (VSMCs), which is modulated by direct and indirect inputs from endothelial cells (ECs).
Samuel N. Baldwin +4 more
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Frontiers in Synaptic Neuroscience, 2022 Recent studies have implicated impaired Parvalbumin Fast-Spiking Interneuron (PVIN) function as a precipitating factor underlying abnormalities in network synchrony, oscillatory rhythms, and cognition associated with Alzheimer’s disease (AD).
Connie A. Mackenzie-Gray Scott +9 more
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Molecules, 2021 Dysphania ambrosioides (L.) Mosyakin and Clemants is an annual or ephemeral perennial herb used traditionally in the Mediterranean region in folk medicine to treat various illnesses, including those related to the digestive system.
Fahd Kandsi +9 more
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Muscarinic Receptors as Targets for Metronomic Therapy in Ovarian Cancer
Düzce Tıp Fakültesi Dergisi, 2023 Aim: In this study, the effects of muscarinic acetylcholine receptor (mAChR) agonist carbachol on the proliferation of cisplatin-resistant (A2780cis) and cisplatin-free (SKOV-3) ovarian cancer cell line were for the first time investigated to further ...
Fatma Söylemez +1 more
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Carbachol and Nicotine in Prefrontal Cortex Have Differential Effects on Sleep-Wake States
Frontiers in Neuroscience, 2020 The role of the brainstem cholinergic system in the regulation of sleep-wake states has been studied extensively but relatively little is known about the role of cholinergic mechanisms in prefrontal cortex in the regulation of sleep-wake states.
Anjum Parkar +11 more
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Life Sciences, Medicine and Biomedicine, 2018 The general notion of activation of Gq-protein coupled receptors involves the mobilisation of stored and extracellular calcium and leads to smooth muscle tissue contraction.
Kayatri Govindaraju +3 more
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