Results 31 to 40 of about 8,575 (176)

In vitro study of spontaneous motility and cholinergic responses in the human Hirschsprung's disease colon

open access: yesFrontiers in Pediatrics
BackgroundThe current standard treatment of Hirschsprung's disease (HD) involves complete resection of the aganglionic intestinal segment with routine rectal irrigation pre- and postoperatively.
Felix Schulze   +7 more
doaj   +1 more source

Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Caand calcineurin-2

open access: yes, 2011
Copyright information:Taken from "Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Caand calcineurin"http://www.biomedcentral.com/1471-2121/8/53BMC Cell Biology 2007;8():53-53.Published online 19 Dec 2007PMCID ...
Dana M García (55215)   +1 more
core   +1 more source

Making Sweat Measurable: Induction, Sampling, and Refreshment in Wearable Biofluid Sensing

open access: yesAdvanced Science, EarlyView.
Wearable sweat sensing relies not only on chemical detection but also on controlled biofluid management. This Review integrates sweat physiology, induction strategies, and microfluidic sampling architectures, demonstrating how flux, transport, and refreshment shape measurement reliability.
Soyoung Shin, Wei Gao
wiley   +1 more source

Clock Genes Regulate Ca2+ Signaling and Mitochondrial Bioenergetics to Inhibit Sjögren Disease

open access: yesArthritis &Rheumatology, EarlyView.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjögren disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA sequencing, and mitochondrial activity were used to investigate the effects of
Viktor R. Drel   +12 more
wiley   +1 more source

Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Caand calcineurin-3

open access: yes, 2011
Copyright information:Taken from "Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Caand calcineurin"http://www.biomedcentral.com/1471-2121/8/53BMC Cell Biology 2007;8():53-53.Published online 19 Dec 2007PMCID ...
Dana M García (55215)   +1 more
core   +1 more source

No influence of carbachol on spontaneous mEPSCs.

open access: yes, 2020
(A) Example traces of recorded mEPSCs in control condition (ctrl, left part), in presence of carbachol (carb, middle part) and after washout carbachol (washout, right part); scale: 2 s/50 pA. The red dots represent the automatically detected mEPSCs.
Stefanie Kurth (3367166)   +2 more
core   +1 more source

Possible approaches to reproduction of endothelial dysfunction. searching for the optimal model

open access: yesФармакокинетика и Фармакодинамика
Purpose of the study. Search for an optimal approach to developing a translational model of endothelial dysfunction (ED).Materials and methods. The experiments were carried out on 58 white male rats, which were randomized into 8 groups: 1st (n = 6 ...
I. B. Tsorin   +5 more
doaj   +1 more source

Ruta graveolens L. in Evidence‐Based Phytotherapy: Pharmacological Activities, Bioactive Compounds and Safety

open access: yesPhytotherapy Research, EarlyView.
Graphical representation of ethnomedical uses, major bioactive compounds, pharmacological potential and toxicological risks of Ruta graveolens L. ABSTRACT Ruta graveolens L. is widely used in traditional European, Asian, African, and South American medicine for digestive, nervous, cardiovascular, respiratory, and reproductive disorders.
Tetiana Serhiienko   +3 more
wiley   +1 more source

Differential segment‐specific signalling pathways for guanylate cyclase C‐activated anion secretion in murine ileocolon

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Guanylate cyclase‐C (GC‐C) is the receptor for endogenous (uro)guanylin peptides, bacterial toxins and pharmacological analogues. Receptor activation leads to intestinal fluid loss, but also activates an antiproliferative pathway and is a promising target in colorectal cancer therapy.
Renjie Xiu   +4 more
wiley   +1 more source

Carbachol-mediated pigment granule dispersion in retinal pigment epithelium requires Ca2+ and calcineurin

open access: yesBMC Cell Biology, 2007
Background Inside bluegill (Lepomis macrochirus) retinal pigment epithelial cells, pigment granules move in response to extracellular signals. During the process of aggregation, pigment motility is directed toward the cell nucleus; in dispersion, pigment
García Dana M, Johnson Adam S
doaj   +1 more source

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