Results 51 to 60 of about 14,304 (180)
Innovative Drug Delivery Systems for the Treatment of Glaucoma
MedComm – Biomaterials and Applications, Volume 5, Issue 2, June 2026.This review aims to provide a comprehensive overview of current topical drug delivery strategies for ocular hypotensive agents in glaucoma therapy. Additionally, it discusses the potential impact of emerging nanotechnological and biomaterial‐based systems in shaping the future of ophthalmic drug delivery, with an emphasis on enhancing efficacy, safety,
Jing Chu +9 more
wiley +1 more source
Gender-differences of in vitro colonic motility after chemo- and radiotherapy in humans
BMC Pharmacology and Toxicology, 2018 Background The aim of the present in vitro study was to investigate, in different genders, motor responses in surgical colonic specimens from patients with rectal cancer undergoing and not undergoing chemotherapy with capecitabine and radiotherapy ...
Maria Antonietta Maselli +6 more
doaj +1 more source
Ca2+‐Activated Cl− Channels: Do Bestrophins and TMEM16A Interact?
Acta Physiologica, Volume 242, Issue 6, June 2026.ABSTRACT Aim Ca2+‐activated Cl– conductances are present in many cell types and are important for regulating membrane potential as well as other cellular functions. TMEM16A is widely accepted as the principal molecular basis for Ca2+‐activated Cl– conductances, but also members of the bestrophin family may be important for some Ca2+‐activated Cl ...
Christian Aalkjær +4 more
wiley +1 more source
Pharmaceutical Biology, 2017 Context: Salsola imbricata Forssk. (Chenopodiaceae) has folkloric repute for the treatment of various gastrointestinal and respiratory ailments. Objective: The present study investigates spasmolytic and bronchorelaxant effects of S. imbricata.
Naveed Aslam, Khalid Hussain Janbaz
doaj +1 more source
Frontiers in Pharmacology, 2020 IntroductionLower urinary tract symptoms (LUTS) due to overactive bladder (OAB) are caused by spontaneous detrusor contractions. Medical treatment with muscarinic receptor antagonists or β3-adrenoceptor agonists aims to inhibit detrusor contractions, but
Bingsheng Li +12 more
doaj +1 more source
Advances in Pharmacological Sciences, 2014 Objective. The objective of this study was to find out the possible antiulcer mechanism of action of Eremomastax speciosa. Method. Carbachol- and histamine-induced hypersecretion, associated with the pylorus ligation technique, were used in rats. Gastric
Amang André Perfusion +3 more
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Journal of Pharmacological Sciences, 2018 Whereas molecular mechanisms of atrial fibrillation (AF) have been widely investigated, there is limited information regarding interrelation between chronic volume overload and parasympathetic nervous system in the pathophysiology of AF.
Xin Cao +5 more
doaj +1 more source
The Role of Muscarinic Receptors on spasmolytic Activity of Hydroalcohlic Extract of Parsley(petroselinum crispum)Seed in Adult Male Rat's Ileum [PDF]
Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016 Background: because of the side effects of chemical drugs, using plant drugs was considered during recent decades. Based on previous studies, various concentrations of plant extracts can reduce ileum contraction caused by KCl and carbachol. Therefore, in
Raede Tavalaee +3 more
doaj
Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings
Biological Research, 2015 BACKGROUND: Ruta graveolens L. (R. graveolens) is a medicinal plant employed in non-traditional medicines that has various therapeutic properties, including anthelmintic, and vasodilatory actions, among others.
Luis Águila +6 more
doaj +1 more source