Results 71 to 80 of about 8,575 (176)

Properties of Carbachol-Induced Oscillatory Activity in Rat Hippocampus

open access: yes, 1997
Williams, John H. and Julie A. Kauer. Properties of carbachol-induced oscillatory activity in rat hippocampus. J. Neurophysiol. 78: 2631–2640, 1997. The recent resurgence of interest in carbachol oscillations as an in vitro model of theta rhythm in the ...
Julie A. Kauer, John H. Williams
core   +1 more source

Gender-differences of in vitro colonic motility after chemo- and radiotherapy in humans

open access: yesBMC Pharmacology and Toxicology, 2018
Background The aim of the present in vitro study was to investigate, in different genders, motor responses in surgical colonic specimens from patients with rectal cancer undergoing and not undergoing chemotherapy with capecitabine and radiotherapy ...
Maria Antonietta Maselli   +6 more
doaj   +1 more source

Design of Experiments, Hirshfeld Surface Analysis, and Pharmacokinetics Predictions of Carbachol‐Loaded Solid Lipid Nanoparticles for Ocular Delivery

open access: yesChemistrySelect, Volume 11, Issue 28, 24 July 2026.
Schematic illustration of the carbachol (CCH)–solid lipid nanoparticles (SLN) formulation, highlighting its structural design of experiments (DoE), physicochemical characterization, Hirshfeld surface analysis and pharmacokinetics predictions. ABSTRACT Carbachol (CCH) is a potent acetylcholine receptor agonist of hydrophilic and charged nature, which ...
Valentina Paganini   +7 more
wiley   +1 more source

An intracellular analysis of gamma-aminobutyric-acid-associated ion movements in rat sympathetic neurones [PDF]

open access: yes, 1985
Double-barrelled ion-sensitive micro-electrodes were used to measure the changes of the intracellular activities of Cl-, K+, and Na+ (aiCl, aiK, aiNa) in neurones of isolated rat sympathetic ganglia during the action of gamma-aminobutyric acid (GABA ...
Ballanyi, Klaus, Grafe, Peter
core  

The effect of varying carbachol concentration on the slope of Schild plots of selective β-adrenoceptor antagonists in the carbachol-contracted guinea-pig trachea

open access: yes, 1986
The effect of varying the level of smooth muscle tone induced by carbachol on the Schild analysis of atenolol (β1-selective) and ICI 118,551 (β2-selective) with salbutamol as agonist, on the guinea-pig tracheal preparation has been examined.
A I Salama, R A Keith, J Y Donahue
core   +1 more source

EFFECT OF CARBACHOL ON FERTILITY OF MALE RATS WHEN ADMINISTERED LOCALLY TO EPIDIDYMIS [PDF]

open access: yes, 2013
This study examines the effect of carbachol, a potent cholinoceptor agonistdrug, on fertility of male rats, when administered to epididymis using stlasticformulations, in the form of rods. 10% and 25% carbachol rods werefound to be toxic, and resulted in
Ratnasooriya, W. D.
core   +1 more source

Clinical Features and Surgical Outcomes of Cats With Presumed Primary Lens Instability: A Retrospective Study of 34 Cases (2018–2022)

open access: yesVeterinary Ophthalmology, Volume 29, Issue 4, July 2026.
ABSTRACT Objective Describe the clinical features, disease progression, and outcomes of presumed primary lens instability (PLI) in cats, and to assess its association with glaucoma. Animals Studied Thirty‐four cats (68 eyes). Procedures Medical records were reviewed for signalment, clinical history, ophthalmic findings, and treatment.
Havi Sarfaty   +5 more
wiley   +1 more source

Antisecretory Action of the Extract of the Aerial Parts of Eremomastax speciosa (Acanthaceae) Occurs through Antihistaminic and Anticholinergic Pathways

open access: yesAdvances in Pharmacological Sciences, 2014
Objective. The objective of this study was to find out the possible antiulcer mechanism of action of Eremomastax speciosa. Method. Carbachol- and histamine-induced hypersecretion, associated with the pylorus ligation technique, were used in rats. Gastric
Amang André Perfusion   +3 more
doaj   +1 more source

Antispasmodic and bronchorelaxant activities of Salsola imbricata are mediated through dual Ca+2 antagonistic and β-adrenergic agonistic effects

open access: yesPharmaceutical Biology, 2017
Context: Salsola imbricata Forssk. (Chenopodiaceae) has folkloric repute for the treatment of various gastrointestinal and respiratory ailments. Objective: The present study investigates spasmolytic and bronchorelaxant effects of S. imbricata.
Naveed Aslam, Khalid Hussain Janbaz
doaj   +1 more source

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