Results 61 to 70 of about 14,304 (180)

Cholinergic Nociceptive Mechanisms in Rat Meninges and Trigeminal Ganglia: Potential Implications for Migraine Pain

open access: yesFrontiers in Neurology, 2017
BackgroundParasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches.
Rashid Giniatullin   +9 more
doaj   +1 more source

Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype

open access: yesJournal of Pharmacological Sciences, 2004
Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi   +5 more
doaj   +1 more source

Phospholipase C Involvement in Activation of the Muscarinic Receptor-Operated Cationic Current in Guinea Pig Ileal Smooth Muscle Cells

open access: yesJournal of Pharmacological Sciences, 2004
In guinea pig single ileal smooth muscle cells held under voltage-clamp, the role of phospholipase C (PLC) in activation of the muscarinic receptor-operated cationic current (Icat) was studied. U73122, a PLC inhibitor, prevented the generation of Icat by
Hiroyuki Okamoto   +7 more
doaj   +1 more source

Unique responses of the fixed stoichiometric TRPC1–TRPC5 concatemer to G proteins

open access: yesFrontiers in Physiology
Transient receptor potential canonical (TRPC)5 channel is a non-selective cation channel that plays a significant role in membrane depolarization and calcium influx. TRPC5 not only forms homotetramers itself but also heterotetramers with TRPC1.
Hana Kang, Insuk So, Insuk So
doaj   +1 more source

Doxazosin Effects on Cholinergic and Adrenergic Responses in Rat Isolated Detrusor Smooth Muscle Preparations From Obstructed Bladder

open access: yesJournal of Pharmacological Sciences, 2004
We investigated the effect of doxazosin on cholinergic and adrenergic agonists responses in detrusor smooth muscle preparations from sham-operated and 2-week partially obstructed rat bladders. Male Wistar albino rats, 200 – 250 g, were randomly allocated
Coşkun Usta   +2 more
doaj   +1 more source

Carbachol as miotic agent in intra-ocular lens implant surgery

open access: yesIndian Journal of Ophthalmology, 1988
The intra cameral use of 0.025% carbachol as a miotic agent in anterior chamber intraocular lens im-plant surgery us reported in 15 cases. Carbachol produced prompt and effective moisis and was found to be harmless and non-irritating to the ...
Agarwal Jitendra
doaj  

Comparisons of urinary bladder responses to common antimuscarinics reveals unique effects of darifenacin

open access: yesFrontiers in Physiology
IntroductionAntimuscarinics are the first-line pharmaceutical treatment for overactive bladder (OAB). However, some literature suggests that responses to these antimuscarinics can influence a variety of non-muscarinic receptors.
Vineesha Veer   +2 more
doaj   +1 more source

COMPARISON OF EFFECTS OF AMMI VISNAGA EXTRACT AND VERAPAMIL ON CARBACHOL STIMULATED GASTRIC SECRETION IN RABBITS

open access: yesGomal Journal of Medical Sciences, 2015
Background: Peptic ulcer is mostly produced due to over production of gastric acid. This study was undertaken to compare the effects of extract from fruits of medicinal plant Ammi visnaga which contains natural calcium channel blocker and verapamil on ...
Subhanullah Jan   +2 more
doaj  

ISEV2026 Abstract Book

open access: yes
Journal of Extracellular Vesicles, Volume 15, Issue S1, June 2026.
wiley   +1 more source

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