Results 81 to 90 of about 8,575 (176)

Influence of chronic volume overload-induced atrial remodeling on electrophysiological responses to cholinergic receptor stimulation in the isolated rat atria

open access: yesJournal of Pharmacological Sciences, 2018
Whereas molecular mechanisms of atrial fibrillation (AF) have been widely investigated, there is limited information regarding interrelation between chronic volume overload and parasympathetic nervous system in the pathophysiology of AF.
Xin Cao   +5 more
doaj   +1 more source

Diabetes-induced rat tracheal segment supersensitivity to carbachol

open access: yes, 1988
Contractile responses to carbachol of tracheal segments isolated (i) from rats made diabetic 4 months prior by a single intravenous injection (50 mg/kg) of streptozotocin (group B), and (ii) from diabetic rats that had been treated during the same ...
A. Michel   +4 more
core   +1 more source

The Role of Muscarinic Receptors on spasmolytic Activity of Hydroalcohlic Extract of Parsley(petroselinum crispum)Seed in Adult Male Rat's Ileum [PDF]

open access: yesMajallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016
Background: because of the side effects of chemical drugs, using plant drugs was considered during recent decades. Based on previous studies, various concentrations of plant extracts can reduce ileum contraction caused by KCl and carbachol. Therefore, in
Raede Tavalaee   +3 more
doaj  

Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings

open access: yesBiological Research, 2015
BACKGROUND: Ruta graveolens L. (R. graveolens) is a medicinal plant employed in non-traditional medicines that has various therapeutic properties, including anthelmintic, and vasodilatory actions, among others.
Luis Águila   +6 more
doaj   +1 more source

Inhibition of carbachol by allopregnanolone.

open access: yes, 2019
The inhibitory dose-response curves for allopregnanolone on carbachol (Cch)-stimulated current, represented as a percentage of the maximal response to Cch. The data are represented as mean ± SEM (n = 5).
Joseph V. Martin (7465346)   +3 more
core   +1 more source

Rapid activation of gluconeogenesis after intracerebroventricular carbachol

open access: yes, 1989
Intracerebroventricular administration of carbachol (27 nmol in 5 microliters 0.15 M NaCl) produced marked hyperglycemia in 24-h fasted rats, despite the negligible amounts of preformed liver glycosyl residues.
M. A. Garofalo   +3 more
core   +1 more source

Cholinergic Nociceptive Mechanisms in Rat Meninges and Trigeminal Ganglia: Potential Implications for Migraine Pain

open access: yesFrontiers in Neurology, 2017
BackgroundParasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches.
Rashid Giniatullin   +9 more
doaj   +1 more source

Analysis of carbachol mediated cell death using xCELLigence technology.

open access: yes, 2013
HEK293-M1 cells were stimulated with various concentrations of carbachol (A), in the presence (or absence) of a M1 selective antagonist (B), and with 5 µM UO126 (C and D).
Michelle Glass (452763)   +6 more
core   +1 more source

Histamine H1 Receptor Down-Regulation Mediated by M3 Muscarinic Acetylcholine Receptor Subtype

open access: yesJournal of Pharmacological Sciences, 2004
Heterologous down-regulation of histamine H1 receptor (H1R) mediated by muscarinic acetylcholine receptor subtype was investigated using five kinds of Chinese hamster ovary (CHO) cells stably co-expressing the human H1R and one of the five (M1 –M5 ...
Katsuhiro Miyoshi   +5 more
doaj   +1 more source

The cholinomimetic agent carbachol induces headache in healthy subjects

open access: yes, 2009
Udgivelsesdato: 2009-FebThe parasympathetic nervous system is likely to be involved in migraine pathogenesis. We hypothesized that the cholinomimetic agonist carbachol would induce headache and vasodilation of cephalic and radial arteries.
Schytz, H W   +6 more
core   +1 more source

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