Results 21 to 30 of about 28,706 (230)

Case report: Acute unintentional carbachol intoxication [PDF]

Critical Care, 2006
Abstract Introduction Intoxications with carbachol, a muscarinic cholinergic receptor agonist are rare. We report an interesting case investigating a (near) fatal poisoning. Methods The son of an 84-year-old male discovered a newspaper ...
Schulz, Martin, Graefe, Thomas, Stuby, Klaus, Andresen, Hilke, Kupfermann, Nikolai, Schmoldt, Achim   +5 more
openaire   +4 more sources

Tetrahydrobiopterin analogues with NO-dependent pulmonary vasodilator properties [PDF]

, 2011
Reduced NO levels due to the deficiency of tetrahydrobiopterin (BH4) contribute to impaired vasodilation in pulmonary hypertension Due to the chemically unstable nature of BH4 it was hypothesised that oxidatively stable analogues of BR, would be able to ...
Gibson, Colin, Kunuthur, S. P., Milliken, P. H., Suckling, C. J., Wadsworth, R. M.   +4 more
core   +1 more source

Ecofriendly Long Life Nanocomposite Sensors for Determination of Carbachol in Presence of Choline: Application in Ophthalmic Solutions and Biological Fluids

Sensors, 2019
Several emerging nano scale forms of carbon are showing great promise in electrochemical sensing such as graphene and multi-walled carbon nanotubes (MWCNTs).
Eman A. Al-Harbi, Mona H. Abdelrahman, Amira M. El-Kosasy   +2 more
doaj   +1 more source

Recovery of hippocampal functions and modulation of muscarinic response by electroacupuncture in young diabetic rats [PDF]

, 2017
The muscarinic receptor response to acetylcholine regulates the hippocampal-related learning, memory, neural plasticity and the production and processing of the pro-nerve growth factor (proNGF) by hippocampal cells.
Berretta, Erica, De Stefano, Maria Egle, Florenzano, Fulvio, Gelfo, Francesca, Manni, Luigi, Nisticã², Robert, Petrosini, Laura, Piccinin, Sonia, Protto, Virginia, Soligo, Marzia   +9 more
core   +2 more sources

Multiple Residues in the Second Extracellular Loop Are Critical for M3 Muscarinic Acetylcholine Receptor Activation [PDF]

, 2007
Recent studies suggest that the second extracellular loop (o2 loop) of bovine rhodopsin and other class I G protein-coupled receptors (GPCRs) targeted by biogenic amine ligands folds deeply into the transmembrane receptor core where the binding of cis ...
Kim, Soo-Kyung, Li, Bo, Scarselli, Marco, Wess, Jürgen   +3 more
core   +1 more source

The Transition Between Slow-Wave Sleep and REM Sleep Constitutes an Independent Sleep Stage Organized by Cholinergic Mechanisms in the Rostrodorsal Pontine Tegmentum

Frontiers in Neuroscience, 2019
There is little information on either the transition state occurring between slow-wave sleep (SWS) and rapid eye movement (REM) sleep, as well as about its neurobiological bases.
Carlos Carrera-Cañas, Miguel Garzón, Isabel de Andrés   +2 more
doaj   +1 more source

Intracellular free sodium and potassium, post-carbachol hyperpolarization, and extracellular potassium-undershoot in rat sympathetic neurones [PDF]

, 1983
Double-barrelled ion-sensitive microelectrodes were used to record the free intracellular Na+- and K+-concentrations ([Na+]i, [K+]i) and to determine their relation to changes in membrane potential and extracellular K+ ([K+]e) in rat sympathetic ganglia.
Brown, Brown, Bührle, Coles, Deitmer, Friedli, Förstl, Grafe, Grafe, Heinemann, Krnjević, Kříž, Lothman, Steiner, Thomas, Ullrich   +15 more
core   +1 more source

Functional evidence that the central renin-angiotensin system plays a role in the pressor response induced by central injection of carbachol

Brazilian Journal of Medical and Biological Research, 1997
We investigated the effects of losartan, an AT1-receptor blocker, and ramipril, a converting enzyme inhibitor, on the pressor response induced by angiotensin II (ANG II) and carbachol (a cholinergic receptor agonist).
W.A. Saad, A.C. Luiz, L.A.A. Camargo, J.E.N. Silveira, S. Fóglia, J.V. Menani, William A. Saad   +6 more
doaj   +1 more source

Autoantibodies against muscarinic receptors in breast cancer: their role in tumor angiogenesis. [PDF]

PLoS ONE, 2013
The presence of autoantibodies in cancer has become relevant in recent years. We demonstrated that autoantibodies purified from the sera of breast cancer patients activate muscarinic acetylcholine receptors in tumor cells.
María Gabriela Lombardi, María Pía Negroni, Laura Tatiana Pelegrina, María Ester Castro, Gabriel L Fiszman, María Eugenia Azar, Carlos Cresta Morgado, María Elena Sales   +7 more
doaj   +1 more source

The role of the tachykinin NK1 receptor in airway changes in a mouse model of allergic asthma [PDF]

, 2004
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De Swert, Katelijne, Joos, Guy, Pauwels, Romain, Tournoy, Kurt   +3 more
core   +2 more sources