Results 91 to 100 of about 43,661 (255)

Pairing the cholinergic agonist carbachol with patterned Schaffer collateral stimulation initiates protein synthesis in hippocampal CA1 pyramidal cell dendrites via a muscarinic, NMDA-dependent mechanism

Journal of Neuroscience, 1993
Effects of afferent stimulation on local synthesis of protein in CA1 pyramidal cell dendrites were studied using light microscope autoradiography. Tissue was fixed with paraformaldehyde immediately after 3 min exposure to 3H-leucine in order to trap 3H ...
S. Feigl, Peter Liptorw
semanticscholar   +1 more source

A polymer coated cicaprost-eluting stent increases neointima formation and impairs vessel function in the rabbit iliac artery [PDF]

, 2016
Drug-eluting stents have been successful in reducing in-stent restenosis but are not suitable for all lesion types and have been implicated in causing late stent thrombosis due to incomplete regeneration of the endothelial cell layer.
Jones, Robert L., Kennedy, Simon, McCormick, Christopher, Mullen, Alexander B., Wadsworth, Roger M.   +4 more
core   +2 more sources

Spontaneous enteric nervous system activity generates contractile patterns prior to maturation of gastrointestinal motility

Neurogastroenterology &Motility, Volume 38, Issue 1, January 2026.
Spontaneous neuronal network activity is critical for circuit maturation, yet whether this is a feature of enteric nervous system development has yet to be established. Here, we identify clustered ripples, a previously undescribed form of neurogenic gastrointestinal motility that shares many features with spontaneous neuronal networks in other systems.
Lori B. Dershowitz, Hassler Bueno Garcia, Andrew S. Perley, Todd P. Coleman, Julia A. Kaltschmidt   +4 more
wiley   +1 more source

Calcium puffs are generic InsP₃-activated elementary calcium signals and are downregulated by prolonged hormonal stimulation to inhibit cellular calcium responses [PDF]

, 2001
Elementary Ca2+ signals, such as "Ca2+ puffs", which arise from the activation of inositol 1,4,5-trisphosphate receptors, are building blocks for local and global Ca2+ signalling.
Berridge, Michael J., Bootman, Martin D., De Smedt, Humbert, de Smet, Patrick, Holmes, Andrew, Lipp, Peter, Missiaen, Ludwig, Parys, Jan B., Thomas, David, Thuring, Jan, Tovey, Stephen C., Young, Kenneth W.   +11 more
core  

Cholinergic modulation of epileptiform activity in the developing rat neocortex [PDF]

, 1989
The effects of carbachol on picrotoxin-induced epileptiform activity and membrane properties of neurons in the developing rat neocortex were examined in an in vitro slice preparation.
Ben-Ari, Benardo, Bernd Sutor, Donoghue, Ferguson, Gutnick, Gähwiler, Haas, Haas, Hablitz, Hablitz, Hablitz, Halliwell, Hounsgaard, John J. Hablitz, Johnston, Kriegstein, Kriegstein, Krnjevic, Krnjevic, Lamour, Lamour, Madison, McCormick, McCormick, McLennan, Metherate, North, Pennefather, Sikes, Stone, Strejckova, Traub, Valentino, Vogt, Yamamoto   +35 more
core   +1 more source

Ultrasonographic Appearance of a Posterior Lenticonus in a Cat

Veterinary Ophthalmology, Volume 29, Issue 1, January 2026.
ABSTRACT The objective of this study is to present high‐quality and up‐to‐date ocular ultrasonographic images and videos of a posterior lenticonus with concomitant mature cataract in a cat. Additionally, the clinical findings, surgical treatment, and outcome are reported for completeness and to confirm the diagnosis.
Antonella Rampazzo, Marc Orts‐Porcar, Francesca Del Chicca   +2 more
wiley   +1 more source

Simultaneous pontine and basal forebrain microinjections of carbachol suppress REM sleep

Journal of Neuroscience, 1993
This study was performed to test the hypothesis that cholinoceptive basal forebrain systems can significantly influence cholinoceptive pontine mechanisms known to be important for generating rapid eye movement (REM) sleep. This hypothesis was examined by
H. Baghdoyan, JL Spotts, SG Snyder
semanticscholar   +1 more source

Multiscale Construction, Evaluation, and Application of Organoids

Advanced Science, Volume 12, Issue 47, December 18, 2025.
Organoids are pivotal models with transformative biomedical potential. A comprehensive multi‐scale perspective is presented, encompassing dual‐scale construction, four‐dimensional evaluation, triple‐point application, and an analysis of the current challenges faced by organoid technology, aiming to advance organoid research and its biomedical ...
Wanting Ma, Zhenglin Dong, Zhu'anzhen Zheng, Long Bai, Xingcai Zhang, Jiacan Su   +5 more
wiley   +1 more source

Pharmacological basis for the medicinal use of cardamom in asthma

Bangladesh Journal of Pharmacology, 2011
Cardamom (Elettaria cardamomum) is widely used in folk medicine for the treatment of asthma. This study describes its airways relaxant potential, with elucidation of possible underlying mechanism.
Arif ullah Khan, Qaiser Jabeen Khan, Anwar Hassan Gilani   +2 more
doaj   +1 more source

Neuromodulatory control of localized dendritic spiking in critical period cortex. [PDF]

, 2019
Sensory experience in early postnatal life, during so-called critical periods, restructures neural circuitry to enhance information processing1. Why the cortex is susceptible to sensory instruction in early life and why this susceptibility wanes with age
Ringach, Dario L, Trachtenberg, Joshua T, Yaeger, Courtney E   +2 more
core