Results 111 to 120 of about 43,661 (255)

Contrasting roles of axonal (pyramidal cell) and dendritic (interneuron) electrical coupling in the generation of neuronal network oscillations [PDF]

, 2003
Electrical coupling between pyramidal cell axons, and between interneuron dendrites, have both been described in the hippocampus. What are the functional roles of the two types of coupling?
Bibbig, A., Buhl, E.H., Hormuzdi, S.G., LeBeau, F.E.N., Monyer, H., Pais, I., Traub, R.D., Whittington, M.A.   +7 more
core   +2 more sources

Influence of chronic volume overload-induced atrial remodeling on electrophysiological responses to cholinergic receptor stimulation in the isolated rat atria

Journal of Pharmacological Sciences, 2018
Whereas molecular mechanisms of atrial fibrillation (AF) have been widely investigated, there is limited information regarding interrelation between chronic volume overload and parasympathetic nervous system in the pathophysiology of AF.
Xin Cao, Megumi Aimoto, Marie Fukumoto, Yoshinobu Nagasawa, Hikaru Tanaka, Akira Takahara   +5 more
doaj   +1 more source

Carbachol, Substance P, and Phorbol Ester Promote the Tyrosine Phosphorylation of Protein Kinase Cδ in Salivary Gland Epithelial Cells (*)

Journal of Biological Chemistry, 1995
The initiation of saliva formation by parotid acinar cells, which comprise the majority of cells in this salivary gland, is initiated by the release of neurotransmitters (acetylcholine, substance P) from parasympathetic nerves. In response to substance P
S. Soltoff, A. Toker
semanticscholar   +1 more source

Antispasmodic and bronchorelaxant activities of Salsola imbricata are mediated through dual Ca+2 antagonistic and β-adrenergic agonistic effects

Pharmaceutical Biology, 2017
Context: Salsola imbricata Forssk. (Chenopodiaceae) has folkloric repute for the treatment of various gastrointestinal and respiratory ailments. Objective: The present study investigates spasmolytic and bronchorelaxant effects of S. imbricata.
Naveed Aslam, Khalid Hussain Janbaz
doaj   +1 more source

Gender-differences of in vitro colonic motility after chemo- and radiotherapy in humans

BMC Pharmacology and Toxicology, 2018
Background The aim of the present in vitro study was to investigate, in different genders, motor responses in surgical colonic specimens from patients with rectal cancer undergoing and not undergoing chemotherapy with capecitabine and radiotherapy ...
Maria Antonietta Maselli, Antonia Ignazzi, Francesco Pezzolla, Annunziata Scirocco, Dionigi Lorusso, Fabrizio De Ponti, Carola Severi   +6 more
doaj   +1 more source

The Role of Muscarinic Receptors on spasmolytic Activity of Hydroalcohlic Extract of Parsley(petroselinum crispum)Seed in Adult Male Rat's Ileum [PDF]

Majallah-i dānishgāh-i ̒ulūm-i pizishkī-i Arāk, 2016
Background: because of the side effects of chemical drugs, using plant drugs was considered during recent decades. Based on previous studies, various concentrations of plant extracts can reduce ileum contraction caused by KCl and carbachol. Therefore, in
Raede Tavalaee, Ahmad Ali Moazedi, Mohammadkazem Gharib Naseri, Mohammadreza Akhond   +3 more
doaj  

Relaxant effects of a hydroalcoholic extract of Ruta graveolens on isolated rat tracheal rings

Biological Research, 2015
BACKGROUND: Ruta graveolens L. (R. graveolens) is a medicinal plant employed in non-traditional medicines that has various therapeutic properties, including anthelmintic, and vasodilatory actions, among others.
Luis Águila, Jenny Ruedlinger, Karina Mansilla, José Ordenes, Raúl Salvatici, Rui Ribeiro de Campos, Fernando Romero   +6 more
doaj   +1 more source

Latent acetylcholinesterase in secretory vesicles isolated from adrenal medulla [PDF]

, 1981
A new procedure is described for the preparation of highly purified and stable secretory vesicles from adrenal medulla. Two forms of acetylcholinesterase, a membrane bound form as well as a soluble form, were found within these vesicles.
Abbs, Anton, Bergmeyer, Blakeborough, Carty, Casey, Chubb, Chubb, Creutz, Dahl, Ekerdt, Ellman, Famborough, Farquar, Gratzl, Gratzl, Gratzl, Ingebretsen, Johnson, Laemmli, Lagercrantz, Leighton, Little, Lowry, Lowry, Meyer, Morris, Morris, Omaye, Palade, Rotundo, Rotundo, Schmidt, Smilowitz, Somogyi, Terland, Terland, Trifaro, Winkler   +38 more
core   +1 more source

Cholinergic Nociceptive Mechanisms in Rat Meninges and Trigeminal Ganglia: Potential Implications for Migraine Pain

Frontiers in Neurology, 2017
BackgroundParasympathetic innervation of meninges and ability of carbachol, acetylcholine (ACh) receptor (AChR) agonist, to induce headaches suggests contribution of cholinergic mechanisms to primary headaches.
Rashid Giniatullin, Rashid Giniatullin, Irina Shelukhina, Irina Shelukhina, Nikita Mikhailov, Polina Abushik, Leniz Nurullin, Leniz Nurullin, Evgeny E. Nikolsky, Evgeny E. Nikolsky   +9 more
doaj   +1 more source

Radioprotective effect of lidocaine on neurotransmitter agonist-induced secretion in irradiated salivary glands. [PDF]

, 2013
Previously we verified the radioprotective effect of lidocaine on the function and ultrastructure of salivary glands in rabbits. However, the underlying mechanism of lidocaine's radioprotective effect is unknown.
Benedek, Geza A., Dendorfer, Andreas, Hakim, Samer G., Klinger, Matthias, Liao, Gui-qing, Meller, Birgit, Rades, Dirk, Sieg, Peter, Su, Yu-xiong   +8 more
core   +3 more sources