Results 81 to 90 of about 74,560 (387)
Simple molecules and complex chemistry in a protoplanetary disk: A JWST investigation of the highly inclined disk d216-0939 [PDF]
A&A 697, A53 (2025)While the number of detected molecules, particularly complex organic molecules, in the solid-state in astrophysical environments is still rather limited, laboratory experiments and astrochemical models predict many potential candidates. Detection of molecules in protoplanetary disks provides a bridge between the chemical evolution of the interstellar ...
arxiv +1 more source
Advanced Science, EarlyView.The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He +6 more
wiley +1 more source
Angewandte Chemie, EarlyView.Pt‐Luc was developed as a pioneering bioluminescent reporter for real‐time monitoring of Pt(IV) reduction in live cells. Using this advanced reporter, we identified that reactive cysteines in proteins, rather than those in small molecules, predominantly mediate the reduction of Pt(IV) prodrugs.
Shu Chen +10 more
wiley +2 more sources
Journal of Medicinal Chemistry, 2016 Radiolabeled urea-based low-molecular weight inhibitors of the prostate-specific membrane antigen (PSMA) are under intense investigation as imaging and therapeutic agents for prostate and other cancers.
Xing Yang +12 more
semanticscholar +1 more source
Novel Electroactive Therapeutic Platforms for Cardiac Arrhythmia Management
Advanced Science, EarlyView.Electroactive platforms offer promising applications in cardiac arrhythmia. Based on their energy sources and mechanisms, electroactive platforms are categorized into i) direct electrical stimulation, ii) self‐powered electroactive systems, iii) physical stimuli‐mediated electroactive systems, and iv) conductive systems, and their applications in ...
Juwei Yang +4 more
wiley +1 more source
Bio-efficacy of selected long-lasting insecticidal nets against pyrethroid resistant Anopheles arabiensis from South-Western Ethiopia. [PDF]
, 2012 The emergence and spread of insecticide resistance in the major African malaria vectors Anopheles gambiae s.s. and Anopheles arabiensis may compromise control initiatives based on insecticide-treated nets (ITNs) or indoor residual spraying (IRS), and ...
Asale, Abebe +5 more
core +3 more sources
Pharmaceuticals, 2022 Pattern 1-hydroxy-N-(2,4,5-trichlorophenyl)-2-naphthamide and the thirteen original carbamates derived from it were prepared and characterized. All the compounds were tested against Staphylococcus aureus ATCC 29213 as a reference and quality control ...
Tomas Gonec +10 more
doaj +1 more source
Advanced Science, EarlyView.PtRuFeCoNi HEA NWs are synthesized by adjusting the metal composition and surface‐engineered with PDA to create HEA NWs@PDA nanozymes with superior catalytic activities and photothermal properties. DFT calculations confirm that self‐polymerized PDA surface engineering moderately lowers the d‐band center of the HEAs, optimizes the surface charge ...
Kunyang Feng +10 more
wiley +1 more source
Angewandte Chemie, EarlyView.Introducing remote silyl groups into coumarin derivatives enhances their hydrolytic stability and photocleavage efficiency. This innovative molecular design enables efficient protein release from solid phase material upon photo irradiation, advancing applications in chemical biology and photomanipulation.
Masahiko Yoshimura +5 more
wiley +2 more sources
Carbamates as Potential Prodrugs and a New Warhead for HDAC Inhibition
Molecules, 2018 We designed and synthesized carbamates of the clinically-approved HDAC (histone deacetylase) inhibitor vorinostat (suberoylanilide hydroxamic acid, SAHA) in order to validate our previously-proposed hypothesis that these carbamates might serve as ...
Kristina King +4 more
doaj +1 more source