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Carbamazepine for schizophrenia [PDF]
Many people with schizophrenia do not achieve a satisfactory treatment response with just antipsychotic drug treatment and various adjunct medications are used to promote additional response. The antiepileptic carbamazepine is one such drug.To evaluate the effects of carbamazepine and its derivatives for the treatment of schizophrenia and related ...
Stefan, Leucht+4 more
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Markedly Elevated Carbamazepine-10,11-epoxide/Carbamazepine Ratio in a Fatal Carbamazepine Ingestion [PDF]
Carbamazepine is a widely used anticonvulsant. Its metabolite, carbamazepine-10,11-epoxide, has been found to display similar anticonvulsant and neurotoxic properties. While the ratio of parent to metabolite concentration varies significantly, at therapeutic doses the epoxide concentration is generally about 20% of the parent. We report a case of fatal
Jason L. Russell+2 more
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Carbamazepine-induced hypogammaglobulinemia [PDF]
Carbamazepine is used to control seizures. Its common side effects are sleep disorders, anorexia, nausea, vomiting, polydipsia, irritability, ataxia, and diplopia. Involvement of the immune system is rare, and few cases of decreased immunoglobulin levels have been reported.
Ozaras, Resat+5 more
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Pharmacogenetics of carbamazepine
Carbamazepine (CMZ) is a drug from the group of anticonvulsants, similar in chemical structure to tricyclic antidepressants. CMZ is widely used for mental disorders and neurological diseases. The lecture discusses the safety of CMZ in respect to personalized medicine, while considering the pharmacogenetic profile of the patient.The authors declare ...
N. A. Shnayder+3 more
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Carbamazepine and Hematological Malignancies [PDF]
Received/Gelis tarihi : May 1, 2013 Accepted/Kabul tarihi : June 10, 2013 To the Editor, The letter entitled “Carbamazepine and Multiple Myeloma: Possible Interaction”, written by Gunaldi et al. [1] and published in one of the recent issues of your journal, was quite interesting. We would like to emphasize some points about that letter. In the reported
Gokhan Sargin+2 more
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Form IV of Carbamazepine [PDF]
Carbamazepine has been found to crystallize as a new polymorph that is stable at room temperature. We report the crystal structure of this C-centered monoclinic form (space group C2/c, cell parameters: a = 26.609, b = 6.9269, c = 13.957, beta = 109.702), which consists of hydrogen bonded dimers with an anti-disposition.
Lang, Meidong+2 more
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Personalizing carbamazepine therapy [PDF]
The anticonvulsant carbamazepine has a high incidence of cutaneous adverse drug reactions. A recent prospective clinical trial in Taiwan has indicated that HLA-B*1502 screening will reduce the incidence of life-threatening adverse reactions to carbamazepine, while a genome-wide association study has identified the HLA-A*3101 allele as a genetic risk ...
Yusuke Nakamura, Taisei Mushiroda
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Carbamazepine‐Induced Tics [PDF]
Summary:A variety of movement disorders are known to occur in association with carbamazepine (CBZ) therapy in adults and children, but development of tics has been described infrequently and only in patients with underlying Tourette's syndrome or other movement disorders.
Robertson, Patricia L.+3 more
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Teratogenicity of Carbamazepine
The teratogenic risk after first trimester exposure to carbamazepine was determined from 210 pregnancies followed prospectively at the Israeli Teratogen Information Service, and Laboratory of Teratology, Hebrew University, Hadassah Medical School, and Ministry of Health, Jerusalem, Israel.
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Carbamazepine: A Therapy for ADHD
The efficacy of carbamazepine (CBZ) in treatment of ADHD has been determined by meta-analysis of 10 reports from the international literature reviewed at Columbia University, St Lukes-Roosevelt Hospital Center, and New York University Medical Center.
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