Results 1 to 10 of about 45,562 (300)

Cilostazol geno-protective effects mitigate carbamazepine-induced genotoxicity in human cultured blood lymphocytes [PDF]

Toxicology Reports
Background: Carbamazepine is one of the most widely used antiepileptic drugs. Carbamazepine has been shown to be toxic to cells. Cilostazol, an antiplatelet agent, has known antioxidant, antiproliferative, anti-inflammatory, and anti-tumor effects ...
Enaam M. Al Momany, Abeer M. Rababa’h, Karem H. Alzoubi, Omar F. Khabour   +3 more
doaj   +2 more sources

Carbamazepine Induces Platelet Apoptosis and Thrombocytopenia Through Protein Kinase A

Frontiers in Pharmacology, 2021
Carbamazepine is extensively used worldwide to treat a wide range of disorders such as epilepsy, peripheral neuralgia and bipolar disorder. Thrombocytopenia and hemorrhage have been identified in multiple carbamazepine-treated patients.
Weiling Xiao, Weiling Xiao, Kangxi Zhou, Mengnan Yang, Chenglin Sun, Lan Dai, Jian Gu, Rong Yan, Kesheng Dai   +8 more
doaj   +1 more source

Combined Structural and Plasmonic Enhancement of Nanometer-Thin Film Photocatalysis for Solar-Driven Wastewater Treatment [PDF]

ACS Applied Nano Materials, 6, 15204-15212, 2023, 2022
Titanium dioxide (TiO$_2$) thin films are commonly used as photocatalytic materials. Here, we enhance the photocatalytic activity of devices based on TiO$_2$ by combining nanostructured glass substrates with metallic plasmonic nanostructures. We achieve a three-fold increase of the catalyst's surface area through nanoscale three-dimensional patterning ...
arxiv   +1 more source

Pharmacokinetics of the CYP3A4 and CYP2B6 Inducer Carbamazepine and Its Drug–Drug Interaction Potential: A Physiologically Based Pharmacokinetic Modeling Approach

Pharmaceutics, 2021
The anticonvulsant carbamazepine is frequently used in the long-term therapy of epilepsy and is a known substrate and inducer of cytochrome P450 (CYP) 3A4 and CYP2B6. Carbamazepine induces the metabolism of various drugs (including its own); on the other
Laura Maria Fuhr, Fatima Zahra Marok, Nina Hanke, Dominik Selzer, Thorsten Lehr   +4 more
doaj   +1 more source

Removal of persistent organic contaminants from wastewater using a hybrid electrochemical-granular activated carbon (GAC) system [PDF]

Journal of Hazardous Materials Journal of Hazardous Materials, Volume 415, 5 August 2021, 125557, 2021
A three-dimensional (3D) electrochemical flow-through reactor equipped with GAC packed bed, polarized by the electric field, was evaluated for the removal of persistent organic contaminants from real sewage effluent. The performance of the reactor was investigated for 27 consecutive runs at two anodic current densities, i.e., low current density (LCD ...
arxiv   +1 more source

Toxicokinetics and correlation of carbamazepine salivary and serum concentrations in acute poisonings [PDF]

Vojnosanitetski Pregled, 2012
Background/Aim. Saliva is a body fluid which, like serum, can be used for determination of concentrations of certain drugs, both in pharmacotherapy as well as in acute poisonings.
Đorđević Snežana, Kilibarda Vesna, Vučinić Slavica, Stojanović Tomislav, Antonijević Biljana   +4 more
doaj   +1 more source

Fabrication of Bi4O5Br2 photocatalyst for carbamazepine degradation under visible-light irradiation

Water Science and Technology, 2021
Bi4O5Br2 with irregular flake shape was synthesized by a facile and energy-saving hydrolysis method. Its band gap energy (Eg) was 2.1 eV. The formation mechanism was proposed.
Xiaoming Mao, Min Li, Mengyao Li
doaj   +1 more source

The effect of multidrug exposure on neurological manifestations in carbamazepine intoxication: a nested case-control study

BMC Pharmacology and Toxicology, 2020
Background In acute intoxication, carbamazepine concentration above 40 mcg/ml is associated with a risk of severe neurological consequences, including depressed consciousness, respiratory depression, cardiac conduction disorders, seizures, and death ...
Ayala Hirsch, Maor Wanounou, Amichai Perlman, Bruria Hirsh-Raccah, Mordechai Muszkat   +4 more
doaj   +1 more source

Carbamazepine overdose after exposure to simethicone: a case report

Journal of Medical Case Reports, 2008
Introduction Carbamazepine is an anticonvulsant drug and is also used as a treatment for patients with manic-depressive illness, post-herpetic neuralgia or phantom limb pain. The drug itself has many drug interactions. Simethicone is an antifoaming agent
Guneysel Ozlem, Onur Ozge, Denizbasi Arzu, Saritemur Murat   +3 more
doaj   +1 more source

A case of hemodialysis and steroid therapy for carbamazepine-induced eosinophilic granulomatosis with polyangiitis: a case report with literature review

Renal Replacement Therapy, 2020
Background Carbamazepine-induced acute kidney injury is mainly caused by acute tubulointerstitial nephritis. Only one case of carbamazepine-induced eosinophilic granulomatosis with polyangiitis (EGPA) with acute kidney injury has been reported.
Tetsuya Abe, Keiko Nishiyama, Takuya Yamazaki, Ryoma Miyasaka, Yukari Honma, Hiroshi Tominaga, Keiko Hashimoto, Takanori Masaki, Fumi Kamata, Mariko Kamata, Togo Aoyama, Takashi Sano, Yasuo Takeuchi, Shokichi Naito   +13 more
doaj   +1 more source