Results 11 to 20 of about 116,665 (387)

Association between HLA-B Alleles and Carbamazepine-Induced Maculopapular Exanthema and Severe Cutaneous Reactions in Thai Patients

open access: yesJournal of Immunology Research, 2018
The HLA-B∗15:02 allele has been reported to have a strong association with carbamazepine-induced Stevens-Johnson syndrome/toxic epidermal necrolysis (SJS/TEN) in Thai patients.
Chonlaphat Sukasem   +17 more
doaj   +2 more sources

Carbamazepine Enhances Adipogenesis by Inhibiting Wnt/β-Catenin Expression

open access: yesCells, 2019
Carbamazepine is a drug that is widely used in the treatment of epilepsy and bipolar disorder. The prevalence of obesity in patients treated with carbamazepine has been frequently reported.
Dong Uk Im   +3 more
doaj   +2 more sources

Efficacy of Carbamazepine and Its Derivatives in the Treatment of Bipolar Disorder

open access: yesMedicina, 2021
Background and Objectives: This review is dedicated to the use of carbamazepine and its derivatives oxcarbazepine and eslicarbazepine in bipolar disorder and their relative strengths in treating and preventing new depressive or manic episodes. This paper
A. Grunze, B. Amann, H. Grunze
semanticscholar   +1 more source

Carbamazepine overdose after exposure to simethicone: a case report

open access: yesJournal of Medical Case Reports, 2008
Introduction Carbamazepine is an anticonvulsant drug and is also used as a treatment for patients with manic-depressive illness, post-herpetic neuralgia or phantom limb pain. The drug itself has many drug interactions. Simethicone is an antifoaming agent
Guneysel Ozlem   +3 more
doaj   +1 more source

Markedly Elevated Carbamazepine-10,11-epoxide/Carbamazepine Ratio in a Fatal Carbamazepine Ingestion [PDF]

open access: yesCase Reports in Medicine, 2015
Carbamazepine is a widely used anticonvulsant. Its metabolite, carbamazepine-10,11-epoxide, has been found to display similar anticonvulsant and neurotoxic properties. While the ratio of parent to metabolite concentration varies significantly, at therapeutic doses the epoxide concentration is generally about 20% of the parent. We report a case of fatal
Jason L. Russell   +2 more
openaire   +3 more sources

Antiepileptic drug carbamazepine promotes horizontal transfer of plasmid-borne multi-antibiotic resistance genes within and across bacterial genera

open access: yesThe ISME Journal, 2018
Antibiotic resistance is a severe global threat for public health, causing around 700,000 deaths per year. Horizontal gene transfer (HGT) is one of the most significant pathways to disseminate antibiotic resistance.
Yue Wang   +6 more
semanticscholar   +1 more source

Antiepileptic Drug Carbamazepine Binds to a Novel Pocket on the Wnt Receptor Frizzled-8

open access: yesJournal of Medicinal Chemistry, 2020
Misregulation of Wnt signaling is common in human cancer. The development of small molecule inhibitors against the Wnt receptor, frizzled (FZD), may have potential in cancer therapy.
Yuguang Zhao   +4 more
semanticscholar   +1 more source

Differential efficacy of lithium and carbamazepine in the prophylaxis of bipolar disorder: Results of the MAP study [PDF]

open access: yes, 2000
In a randomized clinical trial with an observation period of 2.5 years, the differential efficacy of lithium versus carbamazepine was compared in 171 bipolar patients (DSM-IV).
Greil, Waldemar, Kleindienst, Nikolaus
core   +1 more source

The relationship between pharmacokinetic parameters of carbamazepine and therapeutic response in epileptic patients

open access: yesArchives of Medical Science, 2016
Introduction : The prescribed dose and carbamazepine plasma concentration to achieve the optimal therapeutic efficacy are highly variable from one patient to the other.
Chahra Chbili   +6 more
doaj   +1 more source

A case of hemodialysis and steroid therapy for carbamazepine-induced eosinophilic granulomatosis with polyangiitis: a case report with literature review

open access: yesRenal Replacement Therapy, 2020
Background Carbamazepine-induced acute kidney injury is mainly caused by acute tubulointerstitial nephritis. Only one case of carbamazepine-induced eosinophilic granulomatosis with polyangiitis (EGPA) with acute kidney injury has been reported.
Tetsuya Abe   +13 more
doaj   +1 more source

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