Results 191 to 200 of about 77,203 (291)

4β-hydroxycholesterol correlates with dose but not steady-state concentration of carbamazepine: indication of intestinal CYP3A in biomarker formation?

British Journal of Clinical Pharmacology, 2016
Caroline Gjestad, Duy Khanh Huynh, T. Haslemo, E. Molden   +3 more
semanticscholar   +1 more source

IKAROS Associated Immunodeficiency and Thrombotic Thrombocytopenic Purpura

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Pathogenic variants in IKZF1 (IKAROS) are linked to immunodeficiency, malignancy, and immune dysregulation. We describe a family with a rare IKZF1 variant presenting with humoral immunodeficiency and thrombotic thrombocytopenic purpura (TTP). A non‐consanguineous family was clinically monitored; clinical, immunological, and genetic data (exome
Ilia Spivak, Daniella Magen, Karin Weiss, Tamar Paperna, Suhair Hanna, Amos Etzioni, Adi Miller‐Barmak, Yonatan Butbul Aviel   +7 more
wiley   +1 more source

Efficient Degradation of Carbamazepine in Continuous and Batch Modes by Laccase-Photo-Fenton-Intensified Hybrid Treatment. [PDF]

ACS ES T Water
Klanovicz N, Khurana P, Ramos B, Treichel H, Brar SK, Teixeira ACSC.   +5 more
europepmc   +1 more source

Beyond the Michaelis–Menten: Evaluation of a tQSSA‐Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance From Hepatocyte Assays

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 2, February 2026.
ABSTRACT The classical Michaelis–Menten model, under the standard quasi‐steady‐state approximation (sQSSA), is widely used in in vitro‐in vivo extrapolation (IVIVE) studies using hepatocyte or human liver microsomal (HLM) assays to predict intrinsic hepatic clearance (Clint,vitro$$ {\mathrm{Cl}}_{\operatorname{int},\mathrm{vitro}} $$).
Ngoc‐Anh Thi Vu, Yun Min Song, Sang Kyum Kim, Hwi‐yeol Yun, Soyoung Lee, Jae Kyoung Kim, Jung‐woo Chae   +6 more
wiley   +1 more source

Tailoring Anticoagulant Therapy: Managing Interactions Between Carbamazepine and Direct Oral Anticoagulants (DOACs). [PDF]

Cureus
Mohammed TH, Singh PK, Juan Pedro ST, Giordano E, Young B.   +4 more
europepmc   +1 more source

Recent Advances in Metal‐Organic Framework‐Integrated Nanocomposite Hydrogels for Sensors and Sensing Systems

SmartMat, Volume 7, Issue 1, February 2026.
Metal‐organic framework–hydrogel composites are explored as multifunctional materials for next‐generation sensors and sensing systems. This review summarizes recent advances in employing these smart composites to fabricate optical, electrochemical, and electromechanical sensors, emphasizing their potential in healthcare, biomedical diagnostics ...
Md Sazzadur Rahman, Emna Helal, Nicole R. Demarquette   +2 more
wiley   +1 more source

Role of different anti-seizure medications on carotid intima-media thickness: A systematic review and meta-analysis. [PDF]

Medicine (Baltimore)
Davari A, Bahadori AR, Mohammadi-Asl A, Zafari R, Sheikhvatan M, Ranji S, Shafiee S, Tafakhori A.   +7 more
europepmc   +1 more source

Production and Characterization of Carbamazepine Nanocrystals by Electrospraying for Continuous Pharmaceutical Manufacturing

, 2011
Mao Wang, Gregory C. Rutledge, Allan S. Myerson, Bernhardt L. Trout   +3 more
openalex   +2 more sources

Capability, opportunity and motivation for shared decision‐making about valproate as an antiseizure medication treatment for epilepsy in women with pregnancy potential: A qualitative study of patient perspectives

British Journal of Health Psychology, Volume 31, Issue 1, February 2026.
Abstract Objectives Valproate is a highly effective antiseizure medication but carries significant teratogenic and neurodevelopmental risks to offspring if used during pregnancy. A shared decision‐making (SDM) approach is recommended to guide clinician/patient discussions on valproate suitability for women with pregnancy potential.
Sarah Louise Griffiths, Delyth James, Denitza Williams, Lynette James, Andrew Evans, William O. Pickrell, Christine McKnight, Sarah Brown, Rhiannon Phillips   +8 more
wiley   +1 more source

Contaminants of Emerging Concern in Tomatoes Grown in Sludge-Amended Peat: Uptake, Translocation and Risk Assessment. [PDF]

Toxics
Andreasidou E, Kovačič A, Manzano-Sánchez L, Heath D, Pintar M, Kacjan Maršič N, Blaznik U, Rodríguez Fernández-Alba A, Hernando MD, Heath E.   +9 more
europepmc   +1 more source