Results 21 to 30 of about 77,203 (291)

Carbamazepine Associated Prolonged Erection in a Patient with Bipolar Disorder

Psychiatry and Behavioral Sciences, 2012
Carbamazepine is an anticonvulsant which is extensively used in patients with bipolar disorder as a mood stabilizer. Although carbamazepine affects dopamine, norepinephrine and glutamic acid levels in neurons, it mainly shows its effect on sodium and ...
Halil Ozcan, Elif Anıl Yağcıoğlu, Ali Emre Şevik, Ali Cansu Bozacı, Kubilay İnci   +4 more
doaj   +1 more source

Cytochrome P450 3A Induction Predicts P‐glycoprotein Induction; Part 2: Prediction of Decreased Substrate Exposure After Rifabutin or Carbamazepine

Clinical pharmacology and therapy, 2018
Rifampin demonstrated dose‐dependent relative induction between cytochrome P (CYP)3A and P‐glycoprotein (P‐gp), organic anion transporting polypeptides (OATPs), or CYP2C9; P‐gp, OATP, and CYP2C9 induction was one drug–drug interaction (DDI) category ...
J. Lutz, B. Kirby, Lu Wang, Q. Song, J. Ling, B. Massetto, A. Worth, B. Kearney, A. Mathias   +8 more
semanticscholar   +1 more source

Optimization and validation of bioanalytical SPE – HPLC method for the simultaneous determination of carbamazepine and its main metabolite, carbamazepine-10, 11-epoxide, in plasma [PDF]

Makedonsko Farmacevtski Bilten, 2012
Carbamazepine is widely used as an antiepileptic drug in the treatment of partial and generalized tonic-clonic seizures. Carbamazepine 10,11-epoxide is the most important metabolite of carbamazepine, because it is a pharmacologically active compound with
Jasmina Tonic – Ribarska, Zoran Sterjev, Emilija Cvetkovska, Igor Kuzmanovski, Gordana Kiteva, Ljubica Suturkova, Suzana Trajkovic - Jolevska   +6 more
doaj  

Development of ternary solid dispersions with hydrophilic polymer and surface adsorbent for improving dissolution rate of carbamazepine

Saudi Pharmaceutical Journal, 2018
In this study solid dispersions of carbamazepine in the hydrophilic Kollidon® VA64 polymer, adsorbed onto Neusilin® UFL2 adsorption carrier have been employed to improve carbamazepine dissolution rate.
Tanja Vojinović, Djordje Medarević, Edina Vranić, Zorica Potpara, Marko Krstić, Jelena Djuriš, Svetlana Ibrić   +6 more
doaj   +1 more source

Efficacy and safety of eslicarbazepine acetate versus controlled‐release carbamazepine monotherapy in newly diagnosed epilepsy: A phase III double‐blind, randomized, parallel‐group, multicenter study

Epilepsia, 2018
We assessed the efficacy and safety of once‐daily eslicarbazepine acetate in comparison with twice‐daily (BID) controlled‐release carbamazepine (carbamazepine‐CR) monotherapy in newly diagnosed focal epilepsy patients.
E. Trinka, E. Ben-Menachem, P. Kowacs, C. Elger, B. Keller, K. Löffler, J. Rocha, Patrício Soares‐da‐Silva   +7 more
semanticscholar   +1 more source

A Pharmacokinetic Evaluation of a Pectin-Based Oral Multiparticulate Matrix Carrier of Carbamazepine

Advances in Pharmacological and Pharmaceutical Sciences, 2021
Background. Carbamazepine is a drug used in the treatment of neurological disorders such as epilepsy. However, due to its erratic absorption, oral bioavailability is often poor.
Seth Kwabena Amponsah, Simon Yeboah, Kennedy Kwami Edem Kukuia, Benoit Banga N’guessan, Ofosua Adi-Dako   +4 more
doaj   +1 more source

A pro-convulsive carbamazepine metabolite: Quinolinic acid in drug resistant epileptic human brain

Neurobiology of Disease, 2012
Drugs and their metabolites often produce undesirable effects. These may be due to a number of mechanisms, including biotransformation by P450 enzymes which are not exclusively expressed by hepatocytes but also by endothelial cells in brain from ...
Chaitali Ghosh, Nicola Marchi, Mohammed Hossain, Peter Rasmussen, Andreas V. Alexopoulos, Jorge Gonzalez-Martinez, Hu Yang, Damir Janigro   +7 more
doaj   +1 more source

Carbamazepine Overdose after Psychiatric Conditions: A Case Study for Postmortem Analysis in Human Bone

Toxics, 2022
Carbamazepine is the main option used as a preventive medication to treat bipolar disorder when there is no response to lithium. Carbamazepine toxicity is defined as serum levels greater than 12 μg/mL, with severe toxicity occurring over 40 μg/mL ...
Lucia Fernández-López, Rosanna Mancini, Maria-Concetta Rotolo, Javier Navarro-Zaragoza, Juan-Pedro Hernández del Rincón, Maria Falcón   +5 more
doaj   +1 more source

Nationwide Survey of Atopic Myelitis and Plexin D1‐Immunoglobulin G‐Related Pain

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To elucidate the features of plexin D1‐immunoglobulin (Ig)G‐associated neuropathic pain and its relationship to atopic myelitis (AM) in a nationwide Japanese survey. Methods A preliminary survey questionnaire was sent to 1574 selected departments (neurology and pediatrics/pediatric neurology) to explore the numbers of AM and plexin ...
Jun‐ichi Kira, Xu Zhang, Takayuki Fujii, Mikio Mitsuishi, Miho Ushijima, Sato Yoshidomi, Ayako Sakoda, Tomohiro Imamura, Satoshi Kuwabara, Noriko Isobe, Yuri Nakamura   +10 more
wiley   +1 more source

Association of HLA-A*31: 01 Screening With the Incidence of Carbamazepine-Induced Cutaneous Adverse Reactions in a Japanese Population

JAMA Neurology, 2018
Importance Carbamazepine, a commonly used antiepileptic drug, is one of the most common causes of cutaneous adverse drug reactions (cADRs) worldwide.
T. Mushiroda, Yukitoshi Takahashi, T. Onuma, Yoshiaki Yamamoto, T. Kamei, T. Hoshida, Katsuya Takeuchi, Kotaro Otsuka, M. Okazaki, Masako Watanabe, K. Kanemoto, Tomohiro Oshima, A. Watanabe, S. Minami, Kayoko Saito, H. Tanii, Y. Shimo, Minoru Hara, S. Saitoh, T. Kinoshita, Masaki Kato, N. Yamada, Naoki Akamatsu, T. Fukuchi, S. Ishida, S. Yasumoto, A. Takahashi, T. Ozeki, T. Furuta, Yoshiro Saito, N. Izumida, Y. Kano, T. Shiohara, M. Kubo   +33 more
semanticscholar   +1 more source