Results 71 to 80 of about 61,637 (294)
Medications, epilepsy and climate change: Added layers of complexity
British Journal of Clinical Pharmacology, EarlyView.Climate change—the global crisis with pervasive health impacts—has adverse consequences for people with epilepsy (PWE) who have low quality of life due to poor seizure control, socioeconomic disadvantages and comorbidities. This review focuses on the potential effects of climate change on the pharmacological characteristics of antiseizure medications ...
Medine I. Gulcebi +2 more
wiley +1 more source
NQR frequencies of anhydrous carbamazepine polymorphic phases [PDF]
arXiv, 2010 In this work we propose the Nuclear Quadrupole Resonance (NQR) technique as an analytical method suitable for polymorphism detection in active parts (or active principles) of pharmaceuticals with high pharmacological risk. Samples of powder carbamazepine (5H-dibenz(b,f)-azepine-5-carboxamide) are studied.
arxiv
"A COMPARATIVE TRIAL OF LAMOTRIGINE AND CARBAMAZEPINE IN PATIENTS WITH PRIMARY GENERALIZED TONIC CLONIC SEIZURES" [PDF]
Acta Medica Iranica, 2004 Lamotrigine has been used widely in the treatment of partial and secondary generalized seizures. In this study use of lamotrigine as monotherapy for the newly diagnosed primary generalized tonic–clonic seizure has been investigated and compared with ...
H. Ghelichnia +1 more
doaj +2 more sources
Advances in the Release of Amide‐Containing Molecules
Chemistry – A European Journal, Volume 31, Issue 16, March 17, 2025.The ability to release a molecule from a larger construct in a controlled manner is of great importance to produce effective prodrugs, antibody‐drug conjugates, and chemical probes. Amides are ubiquitous functional groups, yet methods to utilise them as molecular release handles are seldom reported.
Thomas Wharton, David R. Spring
wiley +1 more source
Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Nature Communications, 2019 Severe cutaneous adverse reactions (SCAR) is a T cell-mediated, potentially lethal drug hypersensitivity (DH). Here, the authors identify a carbamazepine-specific TCR common among patients with carbamazepine-induced SCAR that confers SCAR-like pathology ...
Ren-You Pan +17 more
doaj +1 more source
British Journal of Clinical Pharmacology, 2016 AIM 4β-hydroxycholesterol (4βOHC) is an endogenous CYP3A(4) biomarker, which is elevated by use of the CYP3A4 inducer carbamazepine. Our aim was to compare to what extent serum concentration of 4βOHC correlates with dose (presystemic exposure) and steady-
Caroline Gjestad +3 more
semanticscholar +1 more source
Removal of benzotriazoles from domestic wastewater using Pleurotus ostreatus fungal pellets
The Canadian Journal of Chemical Engineering, EarlyView.Removal of benzotriazoles from domestic wastewater using a fungal pellet reactor with Pleurotus ostreatus. The system effectively removed CBTR (70%), while BTR (19%), 5‐TTR (17%), and OH‐BTH (16%) showed moderate removal. Abstract Benzotriazoles are a group of persistent and mobile substances commonly found in aquatic environments due to inefficient ...
Evrydiki Markoulatou +3 more
wiley +1 more source
CleanMat, EarlyView.Iron‐based catalysts activate peroxymonosulfate (PMS) to generate high‐valent iron‐oxo species for water decontamination and clean water production. The activation efficiency of PMS varies significantly depending on iron catalyst properties, while the generation of reactive high‐valent iron intermediates is governed by catalyst characteristics ...
Junpeng Guo +8 more
wiley +1 more source
Carbamazepine for acute psychosis with eeg abnormalities [PDF]
Vojnosanitetski Pregled, 2004 Aim. To investigate the efficacy of carbamazepine as adjuvant drug therapy in acute paranoid psychosis with associated EEG abnormalities, compared to sole antipsychotic treatment. Methods.
Ivković Maja +3 more
doaj +1 more source
HLA-A*3101 and carbamazepine-induced hypersensitivity reactions in Europeans.
New England Journal of Medicine, 2011 BACKGROUND Carbamazepine causes various forms of hypersensitivity reactions, ranging from maculopapular exanthema to severe blistering reactions. The HLA-B*1502 allele has been shown to be strongly correlated with carbamazepine-induced Stevens-Johnson ...
M. McCormack +30 more
semanticscholar +1 more source