Results 81 to 90 of about 77,203 (291)

A quick review of carbamazepine pharmacokinetics in epilepsy from 1953 to 2012

Journal of Research in Medical Sciences, 2013
Background: Carbamazepine has been used as AEDs since 1965, and is most effective against partial seizures. Two basic mechanisms of action have been proposed: 1) enhancement of sodium channel inactivation by reducing high-frequency repetitive firing of ...
Zahra Tolou-Ghamari, Mohammad Zare, Jafar Mehvari Habibabadi, Mohammad Reza Najafi   +3 more
doaj  

Cognitive Effects of Carbamazepine and Phenytoin: Reanalysis [PDF]

, 1991
J Gordon Millichap
openalex   +1 more source

Natural language processing‐based emotion and usage analysis of an AI‐powered chatbot for epilepsy support

Epilepsia Open, EarlyView.
Abstract Objective Artificial intelligence (AI)‐powered chatbots are increasingly used for patient education and mental health support, yet their effectiveness in epilepsy care remains underexplored. This study examines text‐based interactions between users and EpiloBot, an epilepsy‐focused chatbot, to understand conversational patterns and emotional ...
Keiichi Watanuki, Ryoya Oba, Naoki Nozawa, Tomoki Ishihara, Koko Oga, Takayuki Iwayama, Takafumi Shiganami, Sayaka Kobayashi, Hironori Kuga, Haruo Yoshimasu, Izumi Kuramochi   +10 more
wiley   +1 more source

A case report: Management of carbamazepine intoxication using hemodialysis followed by continuous venovenous hemodialysis

SAGE Open Medical Case Reports
An 18-year-old woman presented to the emergency department. She had ingested 43 extended-release tablets of carbamazepine 400 mg. Although the patient had high carbamazepine plasma levels and classified as severe intoxication, her clinical symptoms were ...
Heshu Abdullah-Koolmees, Vivian CC Mekel, Agnes I Veldkamp, Martine G Caris, Eleonora L Swart   +4 more
doaj   +1 more source

Purslane protects against the reproductive toxicity of carbamazepine treatment in pilocarpine-induced epilepsy model

Asian Pacific Journal of Tropical Biomedicine, 2017
Objective: To investigate the protective effect of purslane with carbamazepine treatment. Methods: Male albino rats were modulated by pilocarpine to be epileptic.
Widad Makhdour Al-Bishri, Eman Salah Abdel-Reheim, Amr Reda Zaki   +2 more
doaj   +1 more source

Influence of astemizole, an H1 receptor antagonist, on the locomotors activity of carbamazepine and valproate in mice [PDF]

, 2012
Mariusz Świąder, Katarzyna Świąder
openalex   +1 more source

Therapeutic drug monitoring and methods of quantitation for carbamazepine

Journal of Mind and Medical Sciences, 2017
Carbamazepine is an early anticonvulsant still used today in the treatment of several forms of epilepsy. An active metabolite in the human body contributes to its pharmacological effect.
Cristian Tuchila, Daniela L. Baconi, Cristina D. Pirvu, Denisa O. Balalau, Ana M. Vlasceanu, Miriana Stan, Cristian Balalau   +6 more
doaj   +1 more source

Stiripentol use in Dravet syndrome patients in the USA: Results of a real‐world study

Epilepsia Open, EarlyView.
Abstract Objective Dravet syndrome (DS) is a severe developmental and epileptic encephalopathy with a high seizure burden and mortality risk. Stiripentol, one of the first DS‐specific therapies, received FDA approval in 2018 but its real‐world use and impact post‐approval in the USA remain insufficiently characterized.
Elaine Wirrell, James Wheless, Michael Scott Perry, Linda Laux, Karen C. Keough, Julie Ziobro, Aimee F. Luat, Gewalin Aungaroon, Michael A. Ciliberto, Roxane Noel, Laurent Chancharme, Joseph Sullivan   +11 more
wiley   +1 more source

Association between SCN1A polymorphism and carbamazepine‐resistant epilepsy [PDF]

, 2008
Tomohide Abe, Takayuki Seo, Takateru Ishitsu, Takehiro Nakagawa, Masaharu Hori, Kazuko Nakagawa   +5 more
openalex   +1 more source

Neurodevelopmental features in KCNQ2 developmental and epileptic encephalopathy may have limited associations with KV7.2 dysfunction

Epilepsia Open, EarlyView.
Abstract Objective Variants in KCNQ2 encoding the voltage‐gated potassium channel KV7.2 are associated with developmental and epileptic encephalopathy (DEE) of varying severity. This study examined the relationship of KCNQ2 variant dysfunction with the neurodevelopmental phenotype of individuals with KCNQ2‐DEE. Methods A parent‐reported survey gathered
Jessa S. Bidwell, Carlos G. Vanoye, Reshma R. Desai, Anne T. Berg, Alfred L. George Jr   +4 more
wiley   +1 more source