Results 81 to 90 of about 118,649 (387)

CAQ Corner: Basic concepts of transplant immunology

open access: yes, 2022
Liver Transplantation, EarlyView.
Amanda Cheung, Josh Levitsky
wiley   +1 more source

Poloxamer®s anchored with TAT enhance blood–brain barrier penetration of carbamazepine for the treatment of epilepsy: an in vivo study

open access: yesAAPS Open
Carbamazepine is a pharmacological medication commonly prescribed to treat epilepsy. Dose adjustments, poor bioavailability, and prolonged side effects present significant challenges associated with its use.
Farnaz Sotoudegan   +4 more
doaj   +1 more source

Degradation of Carbamazepine in Aqueous Solution Using Ozanation Process [PDF]

open access: yesJournal of Health Sciences and Surveillance System, 2019
Background: Carbamazepine is a pharmaceutical compound used as an anticonvulsant for epilepsy and can enter the environment by inappropriate treatment of hospital wastewater.
Khadijeh Darabi   +2 more
doaj   +1 more source

Targeted monitoring for human pharmaceuticals in vulnerable source and final waters [PDF]

open access: yes, 2012
A range of pharmaceuticals has been detected in soils, surface waters and groundwaters across the world. While the reported concentrations are generally low (i.e. sub μg l-1 in surface waters), the substances have been observed throughout the year across
Bersuder, Phillipe   +6 more
core  

Pharmacogenetics of analgesic drugs [PDF]

open access: yes, 2013
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R   +4 more
core   +1 more source

Refractory Status Epilepticus and Therapeutic Uncertainties: a Comprehensive Review on Targeting Neuroinflammation and Rationale for Developing a Platform Trial

open access: yesAdvanced Science, EarlyView.
Refractory status epilepticus (RSE) is a life‐threatening neurological emergency with high rates of death and long‐term disability, but treatments for it are often based on limited evidence. RSE is now understood to involve neuroinflammation, which has led to the exploration of anti‐inflammatory and immunomodulatory agents like Tocilizumab. Traditional
Shanika Samarasekera   +12 more
wiley   +1 more source

Differential treatment of bipolar disorder with old and new antiepileptic drugs [PDF]

open access: yes, 1998
Although lithium remains the preferred medication for bipolar disorders, new investigations suggest that only 60 to 80% of patients have a good response with a classical presentation.
Berger, M.   +4 more
core   +1 more source

Challenges in Genomic Variant Interpretation Within Pakistani Populations due to Genomic Healthcare Inequalities

open access: yesAmerican Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Accurate classification of genomic variants is crucial to ensure correct diagnosis, genetic counseling, and clinical management of monogenic inherited disorders. Variant interpretation can be hindered in populations that are significantly underrepresented in large reference genomic databases, leading to genomic healthcare inequalities. Despite
Zantasha Khalid   +16 more
wiley   +1 more source

"A COMPARATIVE TRIAL OF LAMOTRIGINE AND CARBAMAZEPINE IN PATIENTS WITH PRIMARY GENERALIZED TONIC CLONIC SEIZURES" [PDF]

open access: yesActa Medica Iranica, 2004
Lamotrigine has been used widely in the treatment of partial and secondary generalized seizures. In this study use of lamotrigine as monotherapy for the newly diagnosed primary generalized tonic–clonic seizure has been investigated and compared with ...
H. Ghelichnia   +1 more
doaj   +2 more sources

Identification of drug-specific public TCR driving severe cutaneous adverse reactions

open access: yesNature Communications, 2019
Severe cutaneous adverse reactions (SCAR) is a T cell-mediated, potentially lethal drug hypersensitivity (DH). Here, the authors identify a carbamazepine-specific TCR common among patients with carbamazepine-induced SCAR that confers SCAR-like pathology ...
Ren-You Pan   +17 more
doaj   +1 more source

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