Results 81 to 90 of about 120,317 (381)

Identification of drug-specific public TCR driving severe cutaneous adverse reactions

Nature Communications, 2019
Severe cutaneous adverse reactions (SCAR) is a T cell-mediated, potentially lethal drug hypersensitivity (DH). Here, the authors identify a carbamazepine-specific TCR common among patients with carbamazepine-induced SCAR that confers SCAR-like pathology ...
Ren-You Pan, Mu-Tzu Chu, Chuang-Wei Wang, Yun-Shien Lee, Francois Lemonnier, Aaron W. Michels, Ryan Schutte, David A. Ostrov, Chun-Bing Chen, Elizabeth Jane Phillips, Simon Alexander Mallal, Maja Mockenhaupt, Teresa Bellón, Wichittra Tassaneeyakul, Katie D. White, Jean-Claude Roujeau, Wen-Hung Chung, Shuen-Iu Hung   +17 more
doaj   +1 more source

Pharmacogenetics of analgesic drugs [PDF]

, 2013
• Individual variability in pain perception and differences in the efficacy of analgesic drugs are complex phenomena and are partly genetically predetermined.
Branford, R, Cregg, R, Gubbay, A, Russo, G, Sato, H   +4 more
core   +1 more source

Synergism and Radicals Dynamics in the Efficient Degradation of Basic Blue 41 via UV/Chlorine Process: Dependence on Processing Conditions

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The UV/chlorine process, a promising advanced oxidation process, demonstrates remarkable synergism and radical dynamics for the efficient degradation of Basic Blue 41 (BB41). This study investigates the effects of processing conditions, including solution temperature (25°C–45°C), pollutant dose (10–40 mg/L), chlorine concentration (100–1000 μM)
Mounia Tidjani, Aissa Dehane, Slimane Merouani, Chawki Djelloul, Oualid Hamdaoui   +4 more
wiley   +1 more source

Effect of zeolites on the reduction of the ecotoxicity of carbamazepine in the environment

Ecotoxicology and Environmental Safety
In this study, the impact of calcination of zeolites on the ecotoxicity of carbamazepine solutions in two matrices, water and synthetic sewage, was assessed.
Aleksandra Bogusz, Beata Tomczyk, Magdalena Trzcińska, Barbara Mirosław, Barbara Gworek   +4 more
doaj   +1 more source

A clinical study on comparative evaluation of the effectiveness of carbamazepine and combination of carbamazepine with baclofen or capsaicin in the management of Trigeminal Neuralgia

Nigerian Journal of Surgery, 2018
Background: Trigeminal neuralgia (TN) is characterized by recurrent attacks of lancinating pain in the trigeminal nerve distribution. Various medicinal and surgical procedures have been utilized for the treatment of TN. Over the time, several drugs other
Nidhi Puri, Akshay Rathore, G Dharmdeep, Swapnil Vairagare, B Rajendra Prasad, R Priyadarshini, Harkanwal Preet Singh   +6 more
doaj   +1 more source

Encapsulation of water insoluble drugs in mesoporous silica nanoparticles using supercritical carbon dioxide [PDF]

, 2011
Mesoporous silica nanoparticles MCM – 41 were synthesized with two dimensional hexagonal p6mm symmetry, high specific surface area(~ 980m2/g) narrow pore size and an average particle size of 186 nm.
Chirmade, U. N., Douroumis, D., Lamprou, D.A., Patil, A., Trivedi, V., Urquart, A.   +5 more
core   +1 more source

Mechanistic Insights Into Photocatalytic Materials for Toxic Pollutants: Environmental Remediation of Personal Care Products

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT Photocatalytic materials have emerged as promising solutions for environmental applications due to their ability to degrade organic pollutants under sunlight or artificial light. In this review, recent progress on the photocatalytic materials used for the degradation of pharmaceutical personal care products (PPCPs) in environmental ...
Urvashi Sen, Gunjan Chauhan, Surbhi Soni, Monika Vats, Anand Kumar, Indra Bahadur   +5 more
wiley   +1 more source

The influence of CYP2C8*3 on carbamazepine serum concentration in epileptic pediatric patients

Balkan Journal of Medical Genetics, 2016
The aim of the present study was to investigate the distribution of CYP2C8 variants *3 and *5, as well as their effect on carbamazepine pharmacokinetic properties, in 40 epileptic pediatric patients on carbamazepine treatment.
Milovanovic DD, Milovanovic JR, Radovanovic M, Radosavljevic I, Obradovic S, Jankovic S, Milovanovic D, Djordjevic N   +7 more
doaj   +1 more source

Management of epilepsy [PDF]

, 1989
Figures for the incidence of epilepsy in Malta are not available. The overall figure for epilepsy given by the Royal College of General Practitioners (Reid 1960) is 4.82 per 1,000 population.
Galea Debono, Anthony
core  

Fe(II)/Chlorine‐Driven Advanced Oxidation of Textile Dyes in a Tubular Microreactor: Continuous‐Flow Performance and Matrix Effects

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT The Fe(II)/chlorine system has emerged as a promising advanced oxidation technology for water treatment, yet its application in continuous‐flow systems remains unexplored. This study presents the first comprehensive investigation of the Fe(II)/chlorine process in a tubular microreactor, a setup that significantly enhances mass transfer and ...
Abderrahmane Talbi, Slimane Merouani, Aissa Dehane   +2 more
wiley   +1 more source