Side effects of phenobarbital and carbamazepine in childhood epilepsy: randomised controlled trial [PDF]
Objective: To compare the behavioural side effects associated with two commonly used antiepilepsy drugs--phenobarbital and carbamazepine--in children in Bangladesh. Design: Prospective randomised controlled single centre trial.
Banu, S.H.+5 more
core
Long-term effect of antiepileptic drug switch on serum lipids and C-reactive protein. [PDF]
BACKGROUND: Prior studies have shown that switching patients from inducing antiepileptic drugs (AEDs) to lamotrigine, levetiracetam, or topiramate reduces serum lipids and C-reactive protein (CRP). These studies were all of short duration, and some drugs,
Chervoneva, Inna+6 more
core +2 more sources
Co-crystal structures of furosemide:urea and carbamazepine:indomethacin determined from powder x-ray diffraction data [PDF]
Co-crystallization is a promising approach to improving both the solubility and the dissolution rate of active pharmaceutical ingredients. Crystal structure determination from powder diffraction data plays an important role in determining co-crystal ...
Al Rahal, Okba+4 more
core +2 more sources
"A COMPARATIVE TRIAL OF LAMOTRIGINE AND CARBAMAZEPINE IN PATIENTS WITH PRIMARY GENERALIZED TONIC CLONIC SEIZURES" [PDF]
Lamotrigine has been used widely in the treatment of partial and secondary generalized seizures. In this study use of lamotrigine as monotherapy for the newly diagnosed primary generalized tonic–clonic seizure has been investigated and compared with ...
H. Ghelichnia+1 more
doaj +2 more sources
Identification of drug-specific public TCR driving severe cutaneous adverse reactions
Severe cutaneous adverse reactions (SCAR) is a T cell-mediated, potentially lethal drug hypersensitivity (DH). Here, the authors identify a carbamazepine-specific TCR common among patients with carbamazepine-induced SCAR that confers SCAR-like pathology ...
Ren-You Pan+17 more
doaj +1 more source
Background: Trigeminal neuralgia (TN) is characterized by recurrent attacks of lancinating pain in the trigeminal nerve distribution. Various medicinal and surgical procedures have been utilized for the treatment of TN. Over the time, several drugs other
Nidhi Puri+6 more
doaj +1 more source
Degradation of Carbamazepine in Aqueous Solution Using Ozanation Process [PDF]
Background: Carbamazepine is a pharmaceutical compound used as an anticonvulsant for epilepsy and can enter the environment by inappropriate treatment of hospital wastewater.
Khadijeh Darabi+2 more
doaj +1 more source
Electrochemical reduction of carbamazepine in ethanol and water solutions using a glassy carbon electrode [PDF]
The electrochemical reduction of carbamazepine in ethanol and water using a glassy carbon electrode has been studied. In all experimental conditions of scan rate and concentration of carbamazepine an irreversible cathodic wave was observed by cyclic ...
Atkins, S.+5 more
core
ABSTRACT Accurate classification of genomic variants is crucial to ensure correct diagnosis, genetic counseling, and clinical management of monogenic inherited disorders. Variant interpretation can be hindered in populations that are significantly underrepresented in large reference genomic databases, leading to genomic healthcare inequalities. Despite
Zantasha Khalid+16 more
wiley +1 more source
Safety profile of oxcarbazepine: results from a prescription-event monitoring study [PDF]
Purpose: To monitor safety of oxcarbazepine, prescribed in primary care in England, using prescription-event monitoring (PEM). Methods: Postmarketing surveillance using observational cohort technique of PEM.
Buggy, Y.+3 more
core +1 more source