Results 91 to 100 of about 655,167 (267)

Detection of Carbapenem-resistant Enterobacteriaceae by Real-Time PCR and Assessment of Hospitalization Related Risk Factors Associated with their Fecal Carriage: A Case-control Study

, 2022
Opportunistic behavior of commensal bacteria during severe infection, especially of the intestine is always considered as a predisposing threat for the severely ill patient admitted to hospitals.
Partha Roy, Manoj Kumar, M. Jeya, Preeti Kumari, Ravikant   +4 more
core   +1 more source

Clinical characteristics, specific resistance patterns, and molecular mechanisms of carbapenem-resistant Morganella morganii isolates

Frontiers in Cellular and Infection Microbiology
ObjectivesThe emergence and spread of carbapenem-resistant Morganella morganii (M. morganii) pose a serious global challenge. This study aimed to investigate the clinical characteristics, resistance patterns, and molecular mechanisms of carbapenem ...
Xiangkuo Zheng, Xiangkuo Zheng, Weiliang Zeng, Yan Liu, Luozhu Feng, Jiayin Zheng, Tieli Zhou, Changrui Qian, Cui Zhou   +8 more
doaj   +1 more source

Whole Genome Characterization of Klebsiella Strains in European Hedgehogs and Human Nosocomial Settings Identified Shared Sequence Types, Antimicrobial Resistance Genes and Plasmids

Zoonoses and Public Health, EarlyView.
ABSTRACT Introduction Klebsiella pneumoniae is a pathogen associated with healthcare‐acquired infections and antimicrobial resistance (AMR) to beta‐lactams and carbapenems. Although wild animals are not typically exposed to antibiotics, they can harbour resistant strains. The European hedgehog (Erinaceus europaeus) is increasingly found in urban areas,
Biel Garcias, Chiara Seminati, Carolin M. Kobras, Samuel K. Sheppard, Rafael A. Molina‐López, Laila Darwich   +5 more
wiley   +1 more source

Epidemiology of carbapenem-resistant Enterobacteriaceae: a 5-year experience at a tertiary care hospital

, 2019
Darunee Chotiprasitsakul,1 Sirawat Srichatrapimuk,2 Suppachok Kirdlarp,1 Alexander D Pyden,3 Pitak Santanirand4 1Division of Infectious Diseases, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand ...
Chotiprasitsakul D, Kirdlarp S, Pyden AD, Srichatrapimuk S, Santanirand P   +4 more
core  

Virulence Factors Of Carbapenem-Resistant Pseudomonas aeruginosa In Hospital-Acquired Infections In Mansoura, Egypt

Infection and Drug Resistance, 2019
Rasha El-Mahdy,1 Ghada El-Kannishy2 1Department of Medical Microbiology And Immunology, Faculty of Medicine, Mansoura University, Mansoura, Egypt; 2Department of Internal Medicine, Faculty of Medicine, Mansoura University, Mansoura, EgyptCorrespondence ...
El-Mahdy R, El-Kannishy G
doaj  

The pivotal role of β‐lactone stereochemistry in the development of SARS‐CoV‐2 Mpro inhibitors

Protein Science, Volume 35, Issue 7, July 2026.
Abstract From the arrival of the SARS‐CoV‐2 coronavirus in 2019 and its associated COVID‐19 pandemic, worldwide efforts have been focused on developing a drug to treat patients. The SARS‐CoV‐2 main protease (Mpro) is one of the main targets for drug design due to its key role in the virus replication and its distinguished ability to cleave peptides ...
Katarzyna Świderek, Vicent Moliner
wiley   +1 more source

Polymyxin B Intravenous Administration Strategy Guided by Minimum Inhibitory Concentration in Critically Ill Patients With Pulmonary Infection: Insights From PBPK Modeling

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
PBPK/PD modeling and clinical retrospective validation of intravenous polymyxin B in critically ill patients with pulmonary infection. ABSTRACT Intravenous polymyxin B (PMB) is widely used for treating drug‐resistant gram‐negative pneumonia, though its efficacy in pulmonary infections is considered limited.
Shengnan Zhang, Nan Yang, Ruwei Yang, Yuanfang Qin, Tingting Wu, Cuifang Wu, Yueliang Xie, Jingjing Liu, Chun Liu, Qi Pei   +9 more
wiley   +1 more source

Estudo de isolados clínicos de Pseudomonas aeruginosa multirresistentes e produtores de metalo-ß-lactamases [PDF]

, 2011
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Biotecnologia e Biociências, Florianópolis, 2011Nas últimas duas décadas, índices crescentes de resistência têm minado a eficácia
Guarneri, Rômulo
core  

Comparative in vitro activity of sitafloxacin against bacteremic isolates of carbapenem resistant Acinetobacter baumannii complex

, 2017
Background: The emergence of carbapenem-resistant Acinetobacter baumannii (CRAB) complex has posed a great challenge to clinicians worldwide. Sitafloxacin has been shown to have in vitro activity against pathogens resistant to other fluoroquinolones ...
Huang, Yu-Shan;Wang, Jann-Tay;Sheng, Wang-Huei;Chuang, Yu-Chung;Chang, Shan-Chwen, 張上淳;盛望徽;王振泰;莊祐中   +1 more
core   +1 more source

Toddlers and terriers: a One Health partnership to combat antimicrobial resistance

Journal of Small Animal Practice, EarlyView.
M. Prodanuk, F. Emdin
wiley   +1 more source