Results 91 to 100 of about 862,573 (173)

Genome-wide sRNA and mRNA transcriptomic profiling insights into carbapenem-resistant Acinetobacter baumannii

Frontiers in Cellular and Infection Microbiology
IntroductionAcinetobacter baumannii (AB) is rising as a human pathogen of critical priority worldwide as it is the leading cause of opportunistic infections in healthcare settings and carbapenem-resistant AB is listed as a “super bacterium” or “priority ...
Yong Wei, Xuli Xin, Jiachun Zhang, Qifeng Liao, Yan Rong, Ying Zhong, Meiying Zhao, Jianping Ma, Song He   +8 more
doaj   +1 more source

Predominance of methicillin-resistant Staphylococcus aureus in the residents and environments of long-term care facilities in Taiwan

Journal of Microbiology, Immunology and Infection, 2019
Background/purpose: This study investigated the distribution and persistence of multidrug resistant organisms (MDROs) including methicillin-resistant Staphylococcus aureus (MRSA), carbapenem-resistant Enterobacteriaceae (CRE), carbapenem-resistant ...
Chia-Ying Liu, Chih-Cheng Lai, Hsiu-Tzy Chiang, Min-Chi Lu, Ling-Fang Wang, Tsai-Ling Tsai, Mei-Yu Kang, Yi-Ni Jan, Yi-Ting Lo, Wen-Chien Ko, Shu-Hui Tseng, Chun-Ming Lee, Po-Ren Hsueh   +12 more
doaj   +1 more source

Epidemiological study of carbapenem-resistant Klebsiella pneumoniae

, 2018
This research is aimed to study the resistance and molecular epidemiological characteristics of carbapenem-resistant Klebsiella pneumoniae (CRKP)
Yang Yan, Cheng Jun, Sun Changgui, Chen Jian, Lin Di   +4 more
core   +1 more source

Microbiological Spectrum and Antimicrobial Resistance Patterns in Tubo‐Ovarian Abscesses Managed by Surgery or Drainage at a Tertiary Hospital in Vietnam: A Retrospective Case Series

Health Science Reports, Volume 9, Issue 11, November 2026.
ABSTRACT Background and Aims Tubo‐ovarian abscess requires empirical antimicrobial therapy before culture results are available, but local antimicrobial resistance data are limited in Vietnam. We described the microbiological spectrum and antimicrobial susceptibility patterns of tubo‐ovarian abscesses managed by surgery or drainage.
Bui Chi Thuong, Huynh Tan An, Pham Dinh Nguyen   +2 more
wiley   +1 more source

Liquid Biopsy: Past, Present, and Future

MedComm, Volume 7, Issue 11, November 2026.
Liquid biopsy has expanded from cancer genotyping to a broader strategy for probing both oncologic and nononcologic conditions through circulating analytes and multilayer molecular readouts. This review traces the field's past, present, and future—summarizing where liquid biopsy is most actionable today, why performance varies across contexts, and ...
Jiachen Liu, Dianjie Zeng, Keran Zhao, Yuxi Wang, Huijie Hu, Fei Deng, Yinhuai Wang, Liya Sun, Liangmin Fu   +8 more
wiley   +1 more source

Antibiotic susceptibility pattern of carbapenem resistant Escherichia coli and Klebsiella pneumoniae, 2019

The Microbe
The rise in the prevalence of carbapenem resistant bacteria worldwide has made the treatment of nosocomial infections challenging. This is because carbapenem resistant bacteria harbor multiple resistance genes aside the carbapenemase genes.
Ibrahim Mohammed Hussaini, Ahmed Babagida Suleiman, Olayeni Stephen Olonitola, Rukayat Avosuahi Oyi   +3 more
doaj   +1 more source

Machine Learning–Augmented Precision Dosing: Integrating Pharmacokinetic Modeling With Clinical Decision Support

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 11, November 2026.
ABSTRACT Inter‐individual variability in drug exposure can lead to ineffective therapy or toxicity, particularly in vulnerable patients. Routine model‐informed precision dosing (MIPD) relies mainly on population pharmacokinetic (PopPK) models, Bayesian forecasting, and therapeutic drug monitoring (TDM).
Yunmeng Pang, Bingqi Zhang, Zhiqiu He, Yuliu Li, Jiaxin Yu, Wei Zuo   +5 more
wiley   +1 more source

Outbreak of resistant Acinetobacter baumannii: measures and proposal for prevention and control

Brazilian Journal of Infectious Diseases
Acinetobacter baumannii colonization and infection, frequent in Intensive Care Unit (ICU) patients, is commonly associated with high morbimortality. Several outbreaks due to multidrug-resistant (MDR) A.
Roberta Maia de Castro Romanelli, Lenize Adriana de Jesus, Wanessa Trindade Clemente, Stella Sala Soares Lima, Edna Maria Rezende, Rosane Luiza Coutinho, Ricardo Luiz Fontes Moreira, Francelli Aparecida Cordeiro Neves, Nelma de Jesus Brás   +8 more
doaj   +1 more source

Phenotypic and Genotypic Characterization of Carbapenem-Resistant Enterobacteriaceae Recovered from a Single Hospital in China, 2013 to 2017

, 2022
Yan Zhang,1 Wenjie Li,1 Xiaomin Tian,1 Ruanyang Sun,1 Shidan Zhou,2 Ling Jia,1 Jian Sun,1,3,4 Xiao-Ping Liao,1,3,4 Ya-Hong Liu,1,3,4 Yang Yu1,3,4 1Guangdong Provincial Key Laboratory of Veterinary Pharmaceutics Development and Safety Evaluation, South ...
Li W, Zhang Y, Tian X, Sun R, Zhou S, Liu YH, Jia L, Liao XP, Sun J, Yu Y   +9 more
core  

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, Volume 600, Issue 19, Page 2947-2960, October 2026.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source