Increased isolation of ESBL producing Klebsiella pneumoniae with emergence of carbapenem resistant isolates in Pakistan: report from a tertiary care hospital [PDF]
OBJECTIVE: To report trends of extended spectrum beta lactamase (ESBL), multidrug resistant (MDR) ESBL and emergence of carbapenem resistant ESBL producing isolates of K. pneumoniae from Pakistan.
Ejaz, Muslima +6 more
core +1 more source
Carbapenem-Resistant Enterobacteriaceae Associated with High Rates of Clinical Failure Despite Best Available Therapy [PDF]
Elise Martin +3 more
openalex +1 more source
Background: Antimicrobial resistance (AMR) is a growing worldwide public health issue due to the overuse and inappropriate use of antibiotics. AMR has been more prevalent during the coronavirus pandemic of 2019 (COVID-19) compared to previous periods ...
Yu-Wei Tseng +3 more
doaj +1 more source
A67 Bloodstream infections by carbapenem-resistant Klebsiella pneumoniae subsp. pneumoniae: Bayesian phylogenetic analysis of whole genomes [PDF]
Eleonora Cella +7 more
openalex +1 more source
Clinical and in vitro efficacy of colistin plus vancomycin and rifampin against colistin-resistant Acinetobacter baumannii causing ventilator-associated pneumonia [PDF]
We present the case of a patient with ventilator-associated pneumonia (VAP) caused by a pan-resistant Acinetobacter baumannii successfully treated with the combination colistin plus vancomycin plus rifampin, whose in vitro activity was investigated by ...
Cipolla, Alessia +5 more
core +1 more source
Phase I Study Assessing the Pharmacokinetic Profile, Safety, and Tolerability of a Single Dose of Ceftazidime-Avibactam in Hospitalized Pediatric Patients. [PDF]
This study aimed to investigate the pharmacokinetics (PK), safety, and tolerability of a single dose of ceftazidime-avibactam in pediatric patients. A phase I, multicenter, open-label PK study was conducted in pediatric patients hospitalized with an ...
Armstrong, Jon +15 more
core
180. Multicenter Analysis of Adequacy of Empiric and Definitive Therapy by Time to Culture Result in Hospitalized Patients with Blood Culture Positive for Carbapenem Resistant and Susceptible Enterobacterales and Pseudomonas aeruginosa [PDF]
Lauren Cooper +6 more
openalex +1 more source
Background Carbapenems are essential antibiotics used to treat severe nosocomial infections. However, the misuse of these antibiotics has led to the emergence of carbapenem-resistant organisms (CROs), posing significant public health threats.
Rula A. M. Aljaede +8 more
doaj +1 more source
Double-carbapenem regimen, alone or in combination with colistin, in the treatment of infections caused by carbapenem-resistant Klebsiella pneumoniae (CR-Kp) [PDF]
Aloj, F. +10 more
core +1 more source

