Results 11 to 20 of about 145,606 (355)

Carbapenem Resistance: A Review [PDF]

Medical Sciences, 2017
Carbapenem resistance is a major and an on-going public health problem globally. It occurs mainly among Gram-negative pathogens such as Klebsiella pneumoniae, Pseudomonas aeruginosa and Acinetobacter baumannii, and may be intrinsic or mediated by ...
F. Codjoe, E. Donkor
semanticscholar   +5 more sources

Mechanisms of resistance to the carbapenems [PDF]

Journal of Antimicrobial Chemotherapy, 1995
M. J. Gill, D. Livingstone, R. Wise
openaire   +4 more sources

The Challenge of Overcoming Antibiotic Resistance in Carbapenem-Resistant Gram-Negative Bacteria: “Attack on Titan”

Microorganisms, 2023
The global burden of bacterial resistance remains one of the most serious public health concerns. Infections caused by multidrug-resistant (MDR) bacteria in critically ill patients require immediate empirical treatment, which may not only be ineffective ...
G. Mancuso, Silvia De Gaetano, A. Midiri, S. Zummo, C. Biondo   +4 more
semanticscholar   +1 more source

An overview of carbapenem-resistant organisms from food-producing animals, seafood, aquaculture, companion animals, and wildlife

Frontiers in Veterinary Science, 2023
Carbapenem resistance (CR) is a major global health concern. CR is a growing challenge in clinical settings due to its rapid dissemination and low treatment options.
Flor Y. Ramírez-Castillo, A. Guerrero-Barrera, F. Avelar-González   +2 more
semanticscholar   +1 more source

Characteristics of Klebsiella bloodstream infections and risk factors for carbapenem-resistant Klebsiella infections in children

Trends in Pediatrics, 2023
Objective: Klebsiella spp. is a common and severe pathogen of bloodstream infections (BSI) due to gram-negative bacilli. Carbapenems are commonly used agents for the treatment of serious infections.
Aysun Yahşi, Gülsüm Iclal Bayhan, Emel Arslan, Muhammed Yasin Gökdöl, Beyza Nur Atay, Seren Karaciğer, Saliha Kanık Yüksek, Belgin Gülhan, Aslınur Özkaya Parlakay   +8 more
doaj   +1 more source

Phenotypic detection of metallo-beta-lactamase production in clinical isolates of Escherichia coli and Klebsiella pneumoniae in a tertiary care hospital

MGM Journal of Medical Sciences, 2022
Introduction: Carbapenem resistance due to metallo-beta-lactamase (MBL)-producing bacteria is an emerging threat worldwide. This study aimed to detect the MBL production in clinical isolates of E.
Smita S Kulkarni, Manjushree V Mulay
doaj   +1 more source

Mechanisms of Action of Carbapenem Resistance

Antibiotics, 2022
Carbapenem antibiotics are the most effective antimicrobials for the treatment of infections caused by the most resistant bacteria. They belong to the category of β-lactams that include the penicillins, cephalosporins, monobactams and carbapenems.
C. Aurilio, P. Sansone, M. Barbarisi, V. Pota, L. G. Giaccari, F. Coppolino, A. Barbarisi, M. Passavanti, M. Pace   +8 more
semanticscholar   +1 more source

First Belgian Report of Ertapenem Resistance in an ST11 Klebsiella Pneumoniae Strain Isolated from a Dog Carrying bla_SCO-1 and bla_DHA-1 Combined with Permeability Defects

Antibiotics, 2022
Klebsiella pneumoniae of sequence type (ST) 11 is a hyper-epidemic nosocomial clone, which is spreading worldwide among humans and emerging in pets. This is the first report, to the best of our knowledge, of multidrug-resistant (MDR) K.
Hanne Debergh, Margo Maex, Cristina Garcia-Graells, Cécile Boland, Marc Saulmont, Koenraad Van Hoorde, Claude Saegerman   +6 more
doaj   +1 more source

Aeromonas dhakensis: Clinical Isolates with High Carbapenem Resistance

Pathogens, 2022
Aeromonas dhakensis is ubiquitous in aquatic habitats and can cause life-threatening septicaemia in humans. However, limited data are available on their antimicrobial susceptibility testing (AST) profiles.
Suat Moi Puah, Wei Ching Khor, Kyaw Thu Aung, Tien Tien Vicky Lau, S. D. Puthucheary, Kek Heng Chua   +5 more
doaj   +1 more source

A review on bacterial resistance to carbapenems: epidemiology, detection and treatment options

Future Science OA, 2020
Carbapenems are a class of antimicrobial agents reserved for infections caused by multidrug-resistant microorganisms. The emergence of carbapenem resistance has become a serious public health threat.
Ann A Elshamy, Khaled M Aboshanab
doaj   +1 more source