Results 31 to 40 of about 101,265 (243)

Pharmacokinetics of Meropenem in People with Cystic Fibrosis—A Proof of Concept Clinical Trial

open access: yesAntibiotics, 2021
Anti-infective treatment of pulmonary exacerbations is a major issue in people with cystic fibrosis (CF). Individualized dosing strategies and adaptation of infusion times are important concepts to optimize anti-infective therapy. In this prospective non-
Jan C. Kamp   +8 more
doaj   +1 more source

Measures to eradicate multidrug-resistant organism outbreaks: How much does it cost? [PDF]

open access: yes, 2015
This study aimed to assess the economic burden of infection control measures that succeeded in eradicating multidrug-resistant organisms (MDROs) in emerging epidemic contexts in hospital settings.
Birgand, GJC   +6 more
core   +1 more source

Virulence Characteristics of Biofilm-Forming Acinetobacter baumannii in Clinical Isolates Using a Galleria mellonella Model

open access: yesMicroorganisms, 2021
Acinetobacter baumannii is a Gram-negative coccobacillus responsible for severe hospital-acquired infections, particularly in intensive care units (ICUs).
Mahmoud A. F. Khalil   +12 more
doaj   +1 more source

Open conversion after aortic endograft infection. Caused by colistin-resistant, carbapenemase-producing Klebsiella pneumoniae [PDF]

open access: yes, 2016
A 62-year-old man presented with fever, abdominal pain, and malaise 13 months after emergency endovascular aortic repair. Computed tomographic angiograms showed a periprosthetic fluid and gas collection, so infection was diagnosed. Open conversion was
Capoccia, Laura   +5 more
core   +1 more source

Investigation of Carbapenemase Genes and Clonal Relationship in Carbapenem Resistant Klebsiella pneumoniae Strains

open access: yesBezmiâlem Science, 2019
Objective:Resistant Gram-negative bacteria isolated from health-related infections are a worldwide problem. Increasing frequency of infections particularly caused by Enterobacteriaceae producing expanded spectrum beta lactamase, leads to the use of more ...
Mustafa SAMASTI   +4 more
doaj   +1 more source

Bloodstream Infections Caused by Carbapenem-Resistant Pathogens in Intensive Care Units: Risk Factors Analysis and Proposal of a Prognostic Score

open access: yesPathogens, 2022
Considering the growing prevalence of carbapenem-resistant Gram-negative bacteria (CR-GNB) bloodstream infection (BSI) in intensive care units (ICUs), the identification of specific risk factors and the development of a predictive model allowing for the ...
Giorgia Montrucchio   +10 more
doaj   +1 more source

Carbapenem resistance in Canada [PDF]

open access: yesCanadian Medical Association Journal, 2009
For more than 2 decades, carbapenems have been considered the pharmacotherapy of last resort for managing multidrug-resistant infections caused by Enterobacteriaceae bacteria (e.g., Escherichia coli and Salmonella ).
Baldwin, Toye   +4 more
openaire   +2 more sources

Molecular Characteristics of First IMP-4-Producing Enterobacter cloacae Sequence Type 74 and 194 in Korea

open access: yesFrontiers in Microbiology, 2017
The worldwide dissemination of carbapenemase-producing Enterobacteriaceae (CPE) has become a major therapeutic concern in clinical settings. Enterobacter cloacae is a major pathogen that causes serious hospital-acquired infections.
Jong Ho Lee   +3 more
doaj   +1 more source

Restoring carbapenem efficacy: a novel carbapenem companion targeting metallo-β-lactamases in carbapenem-resistant Enterobacterales

open access: yesJournal of Antimicrobial Chemotherapy, 2020
AbstractBackgroundThe dissemination of MBLs compromises effective use of many β-lactams in the treatment of patients with life-threatening bacterial infections. Predicted global increases in the prevalence of MBL-producing carbapenem-resistant Enterobacterales (CRE) are being realized, yielding infections that are untreatable with existing therapies ...
Nicola Ooi   +8 more
openaire   +3 more sources

Meropenem Administered via Intravenous Regional Limb Perfusion for Orthopedic Sepsis in Horses: A Clinical Retrospective Study

open access: yesFrontiers in Veterinary Science, 2021
Septic synovitis is a critical orthopedic condition in horses. Early intervention is key, with antibiotic therapy typically initiated prior to culture and susceptibility reports becoming available.
Allison P. Mosichuk   +5 more
doaj   +1 more source

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