Results 11 to 20 of about 30,619 (237)

Therapeutic options for carbapenem-resistant Enterobacteriaceae infections

open access: yesVirulence, 2017
In recent years, carbapenem resistance among Enterobacteriaceae has dramatically increased and represents an important threat to global health. The optimal therapeutic management of carbapenem-resistant Enterobacteriaceae (CRE) infections has not been ...
Tumbarello, Mario   +3 more
core   +2 more sources

Epidemiology and diagnostics of carbapenem resistance in gram-negative bacteria

open access: yesClinical Infectious Diseases, 2019
Carbapenem resistance in gram-negative bacteria has caused a global epidemic that continues to grow. Although carbapenemase-producing Enterobacteriaceae have received the most attention because resistance was first reported in these pathogens in the ...
Nordmann, P.   +5 more
core   +2 more sources

Carbapenem-resistant genes primer sets.

open access: yes, 2023
BackgroundCarbapenem-resistant Enterobacteriaceae (CRE) and Extended-spectrum beta-lactamase (ESBL) production among Gram-negative Enterobacteriaceae is an increasing global challenge due to the high morbidity and mortality associated with their ...
Frank Twum Aboagye (17304867)   +3 more
core   +1 more source

Comparison of Three Phenotypic Methods of Carbapenemase Enzyme Detection to Identify Carbapenem-resistant Enterobacterales [PDF]

open access: yes, 2022
The prevalence of multidrug-resistant gram-negative bacilli has increased worldwide. Critical care areas of most hospitals use carbapenem antibiotics for the empirical treatment of gram-negative bacterial (GNB) infections.
K.V. Leela   +3 more
core   +1 more source

Prevalence of Carbapenem-Resistant Enterobacteriaceae and the Genes Responsible for Carbapenemase Production in a Tertiary Care Hospital in South India [PDF]

open access: yes, 2023
Introduction: Carbapenem resistance in Gram-negative bacilli (GNB) is a major concern in the management of resistant infections. The mechanism of carbapenem resistance is most commonly mediated by carbapenemases. The five most common genes (NDM, KPC, VIM,
Archana Mahalingam   +5 more
core   +1 more source

Parenteral carbapenems [PDF]

open access: yesClinical Microbiology and Infection, 2008
Among the many different structurally distinct classes of beta-lactams, the carbapenem class is regarded as that which is most potent and which has the widest spectrum of antimicrobial activity. Rapidly bactericidal, and demonstrating time-dependent killing, carbapenemes have a spectrum of antimicrobial activity that includes Gram-positive and Gram ...
openaire   +2 more sources

In silico Evolution and Comparative Genomic Analysis of IncX3 Plasmids Isolated From China Over Ten Years

open access: yesFrontiers in Microbiology, 2021
IncX3 plasmids are correlated with the dissemination and acquisition of carbapenem resistance in Enterobacteriaceae and have been prevalent in China over the last 10 years.
Baomo Liu   +7 more
doaj   +1 more source

Identification and infection control of carbapenem-resistant Enterobacterales in intensive care units [PDF]

open access: yesAcute and Critical Care, 2021
Infections with multidrug-resistant organisms among patients in intensive care units (ICUs) are associated with high mortality. Among multidrug-resistant organisms, carbapenem-resistant Enterobacterales (CRE) harbor important pathogens for healthcare ...
Jongyoun Yi, Kye-Hyung Kim
doaj   +1 more source

The complex genetic region conferring transferable antibiotic resistance in multidrug-resistant and extremely drug-resistant Klebsiella pneumoniae clinical isolates

open access: yesNew Microbes and New Infections, 2020
Antibiotic resistance due to transferable resistance genes is one of the most important concerns in Klebsiella pneumoniae isolated from nosocomial infections. Eighty-eight K. pneumoniae isolates were confirmed through biochemical methods.
M.T. Moghadam   +3 more
doaj   +1 more source

Carbapenem Resistant Enterobacteriaceae in Africa

open access: yesBorneo Journal of Pharmacy, 2020
Carbapenems are regarded as unique among the β-lactam antibiotics due to their broad spectrum of activity and ability to resist β-lactamase hydrolysis.
Bashar Haruna Gulumbe, Olumide Ajibola
doaj   +1 more source

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