Results 41 to 50 of about 101,265 (243)

In-vitro evaluation of different antimicrobial combinations with and without colistin against carbapenem-resistant acinetobacter baumannii [PDF]

, 2019
Carbapenem-resistant Acinetobacter baumannii (CR-Ab) infections are associated with high morbidity and mortality. The aim of the study was to evaluate the in-vitro activity of different antimicrobial combinations (with and without colistin, COL) against ...
De Angelis, Massimiliano, Garzoli, Stefania, Marzuillo, Carolina, Mastroianni, Claudio M., Oliva, Alessandra, Ragno, Rino, Vullo, Vincenzo   +6 more
core   +1 more source

Procalcitonin Level Can be a Useful Indicator of When Antibiotics Should be Stepped up in Children with Cancer and Fever without Source

Journal of Health Science and Medical Research (JHSMR), 2022
Objective: To assess whether procalcitonin (PCT) levels can be a reliable indicator of when it is unnecessary to step up antibiotics in children with cancer and fever without source (FWS).
Natthaporn Chumkong, Puttichart Khantee, Kamolwish Laoprasopwattana   +2 more
doaj   +1 more source

Insights into a Novel blaKPC-2-Encoding IncP-6 Plasmid Reveal Carbapenem-Resistance Circulation in Several Enterobacteriaceae Species from Wastewater and a Hospital Source in Spain [PDF]

, 2017
Untreated wastewater, particularly from hospitals and other healthcare facilities, is considered to be a reservoir for multidrug-resistant bacteria.
Cantón, Rafael, Chakraborty, Trinad, Dominguez, Lucas, Falgenhauer, Linda, Imirzalioglu, Can, Lazaro-Perona, Fernando, Mingorance, Jesús, Valverde, Aránzazu, Yao, Yancheng   +8 more
core   +1 more source

Sparing carbapenem usage [PDF]

Journal of Antimicrobial Chemotherapy, 2017
Carbapenem resistance in Gram-negative bacteria is increasing in many countries and use of carbapenems and antibiotics to which resistance is linked should be reduced to slow its emergence. There are no directly equivalent antibiotics and the alternatives are less well supported by clinical trials.
openaire   +3 more sources

Hospital mortality and length of stay associated with Enterobacterales positive blood cultures: a multicenter analysis

Microbiology Spectrum
Delayed time to antimicrobial susceptibility results can impact patients’ outcomes. Our study evaluated the impact of susceptibility turnaround time (TAT) and inadequate empiric antibacterial therapy (IET) in patients with bloodstream infections (BSI ...
Lauren Cooper, Kalvin Yu, Kayla Van Benten, Anuprita Patkar, Gang Ye, Sara Gregory, ChinEn Ai, Vikas Gupta   +7 more
doaj   +1 more source

Discovery on Antibiotic Resistance Patterns of Vibrio parahaemolyticus in Selangor Reveals Carbapenemase Producing Vibrio parahaemolyticus in Marine and Freshwater Fish

Frontiers in Microbiology, 2018
Vibrio parahaemolyticus, a Gram-negative halophilic bacterium is often associated with fish and fishery products, thus causing gastroenteritis in humans upon ingestion of contaminated food. V.
Learn-Han Lee, Learn-Han Lee, Learn-Han Lee, Nurul-Syakima Ab Mutalib, Jodi Woan-Fei Law, Jodi Woan-Fei Law, Sunny Hei Wong, Vengadesh Letchumanan, Vengadesh Letchumanan   +8 more
doaj   +1 more source

A blaVIM-2 Plasmid Disseminating in Extensively Drug-Resistant Clinical Pseudomonas aeruginosa and Serratia marcescens Isolates [PDF]

, 2014
Infections caused by carbapenem-resistant Enterobacteriaceae isolates are an issue of major global concern (1). Genes coding for metallo-β-lactamases (MβLs) identified in clinical isolates are associated with mobile elements and subject to horizontal ...
Centron, Daniela, Deraspe, Maxime, Famiglietti, Angela María Rosa, Kovensky, Jaime, Pistorio, Mariano, Quiroga, Cecilia, Raymond, Frédéric, Rodriguez, Hernan Bernardo, Roy, Paul H., Vilacoba, Elisabet   +9 more
core   +2 more sources

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

A cluster of KPC-2 and VIM-2-producing Klebsiella pneumoniae ST833 isolates from the pediatric service of a Venezuelan Hospital

BMC Infectious Diseases, 2016
Background Klebsiella pneumoniae is a bacterial pathogen that has developed resistance to multiple antibiotics and is a major cause of nosocomial infections worldwide.
Aura Falco, Yusibeska Ramos, Esther Franco, Alegría Guzmán, Howard Takiff   +4 more
doaj   +1 more source

A Chirality‐Converted Bacteriolytic Dodecapeptide Regulates Vibrio‐Induced Polymicrobial Infection and Ameliorates Invasion‐Associated Gut Microbiota Disequilibrium

Advanced Science, EarlyView.
Multidrug‐resistant Vibrio infections are rising rapidly and threaten coastal populations worldwide. This study introduces D‐zp37, a chirality‐engineered antimicrobial peptide with exceptional potency against resistant Vibrio species. D‐zp37 kills planktonic cells, blocks mixed‐species biofilms, disrupts essential bacterial stress responses, and shows ...
Ping Zeng, Qipeng Cheng, Xiaoxu Zhang, Honglan Wang, Jinghan Zhang, Xinyi Ding, Pengfei Zhang, Lanhua Yi, Kwok‐Yin Wong, Kin‐Fai Chan, Sheng Chen, Sharon Shui Yee Leung   +11 more
wiley   +1 more source