Results 21 to 30 of about 30,619 (237)
Frontiers in Cellular and Infection Microbiology, 2022 PurposeThe use of carbapenem before and after implementation of an antimicrobial stewardship-led carbapenem-sparing strategy at a tertiary care center in Lebanon was evaluated.MethodsA retrospective, observational chart review was performed on all ...
Mira El Masri +6 more
doaj +1 more source
Carbapenem-Resistant Enterobacteriaceae [PDF]
Clinics in Laboratory Medicine, 2017 Carbapenem-resistant Enterobacteriaceae (CRE) have emerged as a major threat. Commonly used antibiotics are generally inactive against CRE. Therefore, timely detection of CRE is of paramount importance. Among CRE, those producing carbapenem-hydrolyzing β-lactamase enzymes (carbapenemase-producing Enterobacteriaceae) are particularly of concern because ...
Alina, Iovleva, Yohei, Doi
openaire +2 more sources
Molecular Detection of Carbapenem Resistance in Clinical Isolates of Klebsiella pneumoniae in Tertiary Care Hospital [PDF]
, 2023 Antibiotic resistance has become a serious global threat, mainly due to misuse, overuse of antibiotics and non-compliance with infection control protocol.
Praful S. Patil +5 more
core +1 more source
Angewandte Chemie, EarlyView.Strategic incorporation of unnatural amino acids transforms macrocyclic peptides into drug‐like molecules capable of engaging challenging targets. These building blocks enhance stability, permeability, and bioavailability, accelerating the development of next‐generation peptide therapeutics.
Krishna K. Sharma +5 more
wiley +2 more sources
Structure and Biosynthesis of Mangotoxin Produced by the Plant Pathogen Pseudomonas syringae
Angewandte Chemie, EarlyView.The structure of mangotoxin remained elusive for over two decades. Here, mangotoxin was isolated from the native producer, Pseudomonas syringae pv. syringae, and was determined to be an alkyne‐containing dipeptide. Mangotoxin inhibited the growth of multidrug‐resistant human pathogen Klebsiella pneumoniae.
Alexis H. Murray +4 more
wiley +2 more sources
Van Tıp Dergisi, 2023 INTRODUCTION: The profile of carbapenem-resistant Enterobacterales (CRE), antibiotic susceptibilities were analyzed in our hospital providing a wide range of healthcare services in Southeastern Anatolia.
Çiğdem Mermutluoğlu +3 more
doaj +1 more source
SURVEILLANCE OF CARBAPENEM-RESISTANT GRAM-NEGATIVE BACTERIA FROM ANIMAL SOURCES IN MATHURA REGION, UTTAR PRADESH, INDIA [PDF]
Exploratory Animal and Medical Research, 2022 A cross-sectional study was conducted to determine the prevalence of Carbapenem-resistant Gram-negative bacteria (CR-GNB) in animals. The study involves one hundred eighty-four GNB isolates from 214 samples (feces, milk, pus, and uterine discharge ...
A. Arun +5 more
doaj +1 more source
New developments in carbapenems [PDF]
Clinical Microbiology and Infection, 2008 Antibiotic resistance among Gram-negative pathogens in hospitals is a growing threat to patients and is driving the increased use of carbapenems. Carbapenems are potent members of the beta-lactam family of antibiotics, with a history of safety and efficacy for serious infections that exceeds 20 years. Original and review articles were identified from a
Kattan, J.N. +2 more
openaire +2 more sources
Global Incidence of Carbapenemase-Producing Escherichia coli ST131
Emerging Infectious Diseases, 2014 We characterized Escherichia coli ST131 isolates among 116 carbapenemase-producing strains. Of isolates from 16 countries collected during 2008–2013, 35% belonged to ST131 and were associated with blaKPC, H30 lineage, and virotype C. This study documents
Gisele Peirano +6 more
doaj +1 more source
Antibiotics, 2023 As antibiotic resistance has become a global problem, the intervention of an antimicrobial stewardship team (AST) is warranted. In hematological disorders, infectious complications are crucial owing to abnormal neutrophil function and decreased cell ...
Ayako Suzuki +12 more
doaj +1 more source